GSK2636771
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- $11 - $2245.7
- Product name: GSK2636771
- CAS: 1372540-25-4
- MF: C22H22F3N3O3
- MW: 433.42
- EINECS:
- MDL Number:MFCD22417098
- Synonyms:GSK2636771;2-Methyl-1-[[2-Methyl-3-(trifluoroMethyl)phenyl]Methyl]-6-(4-Morpholinyl)-1H-benziMidazole-4-carboxylic acid;GSK2636771/GSK-2636771;GSK 2636771 dihydrochloride;2-Methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic;1H-Benzimidazole-4-carboxylic acid, 2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-(4-morpholinyl)-;2-Methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylic acid GSK2636771;2-METHYL-1-[[2-METHYL-3-(TRIFLUOROMETHYL)PHENYL]METHYL]-6-MORPHOLIN-4-YLBENZIMIDAZOLE-4-CARBOXYLIC ACID
54 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 500μg
- 2x5mg
- 25mg
- 2x25mg
- 2.5mg
- 25.00mg
- 100.00mg
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 50mg
- 100MG
- 250MG
- 1G
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA009C9B
- Product description2-Methyl-1-(2-Methyl-3-(Trifluoromethyl)Benzyl)-6-Morpholino-1H-Benzo[D]Imidazole-4-Carboxylic Acid 99%
- Packaging1mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009C9B
- Product description2-Methyl-1-(2-Methyl-3-(Trifluoromethyl)Benzyl)-6-Morpholino-1H-Benzo[D]Imidazole-4-Carboxylic Acid 99%
- Packaging5mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009C9B
- Product description2-Methyl-1-(2-Methyl-3-(Trifluoromethyl)Benzyl)-6-Morpholino-1H-Benzo[D]Imidazole-4-Carboxylic Acid ≥98%
- Packaging10mg
- Price$35
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberL14953
- Product descriptionGSK-2636771 98%
- Packaging100MG
- Price$120
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL14953
- Product descriptionGSK-2636771 98%
- Packaging250MG
- Price$240
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL14953
- Product descriptionGSK-2636771 98%
- Packaging1G
- Price$720
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5712
- Product descriptionGSK2636771
- Packaging50mg
- Price$757
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5712
- Product descriptionGSK2636771
- Packaging100mg
- Price$1296
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging50MG
- Price$1443.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging5MG
- Price$786.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging10MG
- Price$866.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging1MG
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2186
- Product descriptionGSK2636771
- Packaging50mg
- Price$432
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB2186
- Product descriptionGSK2636771
- Packaging10mg
- Price$185
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB2186
- Product descriptionGSK2636771
- Packaging5mg
- Price$98
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB2186
- Product descriptionGSK2636771
- Packaging10mM(in1mLDMSO)
- Price$66
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009C9B | 2-Methyl-1-(2-Methyl-3-(Trifluoromethyl)Benzyl)-6-Morpholino-1H-Benzo[D]Imidazole-4-Carboxylic Acid 99% | 1mg | $11 | 2026-05-28 | Buy |
| aablocks | AA009C9B | 2-Methyl-1-(2-Methyl-3-(Trifluoromethyl)Benzyl)-6-Morpholino-1H-Benzo[D]Imidazole-4-Carboxylic Acid 99% | 5mg | $20 | 2026-05-28 | Buy |
| aablocks | AA009C9B | 2-Methyl-1-(2-Methyl-3-(Trifluoromethyl)Benzyl)-6-Morpholino-1H-Benzo[D]Imidazole-4-Carboxylic Acid ≥98% | 10mg | $35 | 2026-05-28 | Buy |
| ACHEMBLOCK | L14953 | GSK-2636771 98% | 100MG | $120 | 2026-05-27 | Buy |
| ACHEMBLOCK | L14953 | GSK-2636771 98% | 250MG | $240 | 2026-05-27 | Buy |
| ACHEMBLOCK | L14953 | GSK-2636771 98% | 1G | $720 | 2026-05-27 | Buy |
| AK Scientific | SYN5712 | GSK2636771 | 50mg | $757 | 2021-12-16 | Buy |
| AK Scientific | SYN5712 | GSK2636771 | 100mg | $1296 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 50MG | $1443.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 5MG | $786.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 10MG | $866.25 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 1MG | $470 | 2021-12-16 | Buy |
| ApexBio Technology | B2186 | GSK2636771 | 50mg | $432 | 2026-05-06 | Buy |
| ApexBio Technology | B2186 | GSK2636771 | 10mg | $185 | 2026-05-06 | Buy |
| ApexBio Technology | B2186 | GSK2636771 | 5mg | $98 | 2026-05-06 | Buy |
| ApexBio Technology | B2186 | GSK2636771 | 10mM(in1mLDMSO) | $66 | 2026-05-06 | Buy |
Properties
Melting point :>225°C (dec.)
Boiling point :641.3±55.0 °C(Predicted)
Density :1.38
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :-2.70±0.30(Predicted)
form :Solid
color :Pale Yellow
InChI :InChI=1S/C22H22F3N3O3/c1-13-15(4-3-5-18(13)22(23,24)25)12-28-14(2)26-20-17(21(29)30)10-16(11-19(20)28)27-6-8-31-9-7-27/h3-5,10-11H,6-9,12H2,1-2H3,(H,29,30)
InChIKey :XTKLTGBKIDQGQL-UHFFFAOYSA-N
SMILES :C1(C)N(CC2=CC=CC(C(F)(F)F)=C2C)C2=CC(N3CCOCC3)=CC(C(O)=O)=C2N=1
Boiling point :641.3±55.0 °C(Predicted)
Density :1.38
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :-2.70±0.30(Predicted)
form :Solid
color :Pale Yellow
InChI :InChI=1S/C22H22F3N3O3/c1-13-15(4-3-5-18(13)22(23,24)25)12-28-14(2)26-20-17(21(29)30)10-16(11-19(20)28)27-6-8-31-9-7-27/h3-5,10-11H,6-9,12H2,1-2H3,(H,29,30)
InChIKey :XTKLTGBKIDQGQL-UHFFFAOYSA-N
SMILES :C1(C)N(CC2=CC=CC(C(F)(F)F)=C2C)C2=CC(N3CCOCC3)=CC(C(O)=O)=C2N=1
Safety Information
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Description
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol at the 3 position to produce the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3). Class 1 PI3Ks are composed of a p110 catalytic subunit, of which there are four isoforms (p110α, p110β, p110δ, and p100γ), and a p85 regulatory subunit. GSK2636771 is an orally bioavailable inhibitor of PI3K p110β. At 1-10 μM, it decreases cell viability and Akt phosphorylation in p100β-dependent PTEN-deficient PC-3 prostate and BT549 and HCC70 breast cancer cell lines.More related product prices
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Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Chembest Research Laboratories Limited
Jinan Trio PharmaTech Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
NCE Biomedical Co.,Ltd.
Haoyuan Chemexpress Co., Ltd.
Shanghai Aladdin Bio-Chem Technology Co.,LTD
MedChemexpress LLC
Guangzhou Isun Pharmaceutical Co., Ltd
AdooQ BioScience, LLC