GSK4027
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- $44 - $3950
- Product name: GSK4027
- CAS: 2079896-25-4
- MF: C17H21BrN4O
- MW: 377.28
- EINECS:
- MDL Number:MFCD31692324
- Synonyms:GSK4027;GSK4207;3(2H)-Pyridazinone, 4-bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenyl-3-piperidinyl]amino]-
37 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25MG
- 10mM*1mLinDMSO(Solid+Solvent)
- 50MG
- 100mg
- Manufactureraablocks
- Product numberAA01ENUF
- Product descriptionGSK4027 ≥95%
- Packaging1mg
- Price$49
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENUF
- Product descriptionGSK4027 ≥95%
- Packaging5mg
- Price$154
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENUF
- Product descriptionGSK4027 ≥95%
- Packaging10mg
- Price$283
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143248
- Product description4-Bromo-2-methyl-5-[(cis-1-methyl-5-phenyl-3-piperidinyl)amino]pyridazin-3(2H)-one 98%
- Packaging5MG
- Price$185
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143248
- Product description4-Bromo-2-methyl-5-[(cis-1-methyl-5-phenyl-3-piperidinyl)amino]pyridazin-3(2H)-one 98%
- Packaging50MG
- Price$1100
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143248
- Product description4-Bromo-2-methyl-5-[(cis-1-methyl-5-phenyl-3-piperidinyl)amino]pyridazin-3(2H)-one 98%
- Packaging25MG
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3339EJ
- Product description4-Bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenylpiperidin-3-yl]amino]pyridazin-3-one
- Packaging5mg
- Price$253
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-101027
- Product descriptionGSK 4027 98.22%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$130
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101027
- Product descriptionGSK 4027 98.22%
- Packaging10mM*1mLinDMSO(Solution)
- Price$136
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101027
- Product descriptionGSK 4027 98.22%
- Packaging5mg
- Price$124
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101027
- Product descriptionGSK 4027 98.22%
- Packaging100mg
- Price$1188
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101027
- Product descriptionGSK 4027 98.22%
- Packaging25mg
- Price$428
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101027
- Product descriptionGSK 4027 98.22%
- Packaging10mg
- Price$209
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101027
- Product descriptionGSK 4027 98.22%
- Packaging50mg
- Price$722
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberBG166671
- Product descriptionGSK 4027
- Packaging10mg
- Price$448.3
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBG166671
- Product descriptionGSK 4027
- Packaging10mg
- Price$285
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01ENUF | GSK4027 ≥95% | 1mg | $49 | 2026-05-30 | Buy |
| aablocks | AA01ENUF | GSK4027 ≥95% | 5mg | $154 | 2026-05-30 | Buy |
| aablocks | AA01ENUF | GSK4027 ≥95% | 10mg | $283 | 2026-05-30 | Buy |
| ACHEMBLOCK | V143248 | 4-Bromo-2-methyl-5-[(cis-1-methyl-5-phenyl-3-piperidinyl)amino]pyridazin-3(2H)-one 98% | 5MG | $185 | 2026-05-27 | Buy |
| ACHEMBLOCK | V143248 | 4-Bromo-2-methyl-5-[(cis-1-methyl-5-phenyl-3-piperidinyl)amino]pyridazin-3(2H)-one 98% | 50MG | $1100 | 2026-05-27 | Buy |
| ACHEMBLOCK | V143248 | 4-Bromo-2-methyl-5-[(cis-1-methyl-5-phenyl-3-piperidinyl)amino]pyridazin-3(2H)-one 98% | 25MG | $650 | 2026-05-27 | Buy |
| AK Scientific | 3339EJ | 4-Bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenylpiperidin-3-yl]amino]pyridazin-3-one | 5mg | $253 | 2021-12-16 | Buy |
| Arctom | HY-101027 | GSK 4027 98.22% | 10mM*1mLinDMSO(Solid+Solvent) | $130 | 2026-05-26 | Buy |
| Arctom | HY-101027 | GSK 4027 98.22% | 10mM*1mLinDMSO(Solution) | $136 | 2026-05-26 | Buy |
| Arctom | HY-101027 | GSK 4027 98.22% | 5mg | $124 | 2026-05-26 | Buy |
| Arctom | HY-101027 | GSK 4027 98.22% | 100mg | $1188 | 2026-05-26 | Buy |
| Arctom | HY-101027 | GSK 4027 98.22% | 25mg | $428 | 2026-05-26 | Buy |
| Arctom | HY-101027 | GSK 4027 98.22% | 10mg | $209 | 2026-05-26 | Buy |
| Arctom | HY-101027 | GSK 4027 98.22% | 50mg | $722 | 2026-05-26 | Buy |
| Biosynth | BG166671 | GSK 4027 | 10mg | $448.3 | 2026-06-04 | Buy |
| Biosynth | BG166671 | GSK 4027 | 10mg | $285 | 2021-12-16 | Buy |
Properties
Boiling point :450.3±55.0 °C(Predicted)
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:50.0(Max Conc. mg/mL);132.53(Max Conc. mM)
form :A crystalline solid
pka :9.58±0.10(Predicted)
color :Light yellow to yellow
InChI :1S/C17H21BrN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3/t13-,14+/m0/s1
InChIKey :VZAFGXCWAWRULT-UONOGXRCSA-N
SMILES :CN(C[C@H](C1)C2=CC=CC=C2)C[C@@H]1NC(C=NN(C3=O)C)=C3Br
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:50.0(Max Conc. mg/mL);132.53(Max Conc. mM)
form :A crystalline solid
pka :9.58±0.10(Predicted)
color :Light yellow to yellow
InChI :1S/C17H21BrN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3/t13-,14+/m0/s1
InChIKey :VZAFGXCWAWRULT-UONOGXRCSA-N
SMILES :CN(C[C@H](C1)C2=CC=CC=C2)C[C@@H]1NC(C=NN(C3=O)C)=C3Br
Safety Information
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Description
GSK4027 is a potent and selective chemical probe for the PCAF/GCN5 bromodomain. GSK4027 has PCAF TR-FRET pIC50 = 7.4 ; PCAF BROMOscan pKi = 8.9; GCN5 BROMOscan pKi = 8.9; PCAF NanoBRET pIC50 =7.2; BRD4 BD1 TR-FRET pIC50 < 4.3. GSK4027 shows high potency for the PCAF/GCN5 bromodomain, high solubility, cellular target engagement, and ≥18000-fold selectivity over the BET family, together with ≥70-fold selectivity over the wider bromodomain families. p300/CREB binding protein associated factor (PCAF/KAT2B) and general control nonderepressible 5 (GCN5/KAT2A) are multidomain proteins that have been implicated in retroviral infection, inflammation pathways, and cancer development.Suppliers and manufacturers
TargetMol Chemicals Inc.
Aladdin Scientific
Shanghai Haozhixiang Biotechnology Co., Ltd
BOC Sciences
BOC Sciences
Shanghai YuanYe Biotechnology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Shanghai hongqu biomedical technology co. LTD
Kaifeng Mingren Pharmaceutical Co.,LTD
