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ChemicalBook >> CAS DataBase List >> GlyH-101

GlyH-101

GlyH-101 price.
  • $25 - $1470
  • Product name: GlyH-101
  • CAS: 328541-79-3
  • MF: C19H15Br2N3O3
  • MW: 493.15
  • EINECS:
  • MDL Number:MFCD01532954
  • Synonyms:(NAPHTHALEN-2-YLAMINO)-ACETIC ACID (3,5-DIBROMO-2,4-DIHYDROXY-BENZYLIDENE)-HYDRAZIDE;GLYH-101;Glycine, N-2-naphthalenyl-, [(3,5-dibroMo-2,4-dihydroxyphenyl)Methylene]hydrazide;N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;N-2-Naphthalenylglycine [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;GlyH 101 N-2-Naphthalenylglycine [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;N-2-Naphthalenylglycine [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide CFTR Inhibitor II;CFTR Inhibitor II, GlyH-101
21 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 10
  • 100mg
  • 50
  • 50mg
  • 10mM(in 1mL DMSO)
  • 1g
  • ManufacturerAK Scientific
  • Product number3698AH
  • Product description(Naphthalen-2-ylamino)-aceticacid(3,5-dibromo-2,4-dihydroxy-benzylidene)-hydrazide
  • Packaging1g
  • Price$721
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1087
  • Product descriptionGlyH-101
  • Packaging10mM(in 1mL DMSO)
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1087
  • Product descriptionGlyH-101
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1087
  • Product descriptionGlyH-101
  • Packaging50mg
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15772
  • Product descriptionCFTR Inhibitor II ≥95%
  • Packaging1mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15772
  • Product descriptionCFTR Inhibitor II ≥95%
  • Packaging5mg
  • Price$41
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15772
  • Product descriptionCFTR Inhibitor II ≥95%
  • Packaging10mg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15772
  • Product descriptionCFTR Inhibitor II ≥95%
  • Packaging25mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15772
  • Product descriptionCFTR Inhibitor II ≥95%
  • Packaging50mg
  • Price$263
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM141563
  • Product description(E)-N''-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98%
  • Packaging10mg
  • Price$122
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM141563
  • Product description(E)-N''-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98%
  • Packaging50mg
  • Price$467
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2098
  • Product descriptionGlyH-101 99.00%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2098
  • Product descriptionGlyH-101 99.00%
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2098
  • Product descriptionGlyH-101 99.00%
  • Packaging50mg
  • Price$624
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002238
  • Product descriptionGlyH-101 98+%
  • Packaging50mg
  • Price$697
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7039
  • Product descriptionCFTRInhibitorII >98%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3698AH (Naphthalen-2-ylamino)-aceticacid(3,5-dibromo-2,4-dihydroxy-benzylidene)-hydrazide 1g $721 2021-12-16 Buy
ApexBio Technology B1087 GlyH-101 10mM(in 1mL DMSO) $85 2021-12-16 Buy
ApexBio Technology B1087 GlyH-101 10mg $125 2021-12-16 Buy
ApexBio Technology B1087 GlyH-101 50mg $525 2021-12-16 Buy
Cayman Chemical 15772 CFTR Inhibitor II ≥95% 1mg $25 2021-12-16 Buy
Cayman Chemical 15772 CFTR Inhibitor II ≥95% 5mg $41 2024-03-01 Buy
Cayman Chemical 15772 CFTR Inhibitor II ≥95% 10mg $73 2024-03-01 Buy
Cayman Chemical 15772 CFTR Inhibitor II ≥95% 25mg $142 2024-03-01 Buy
Cayman Chemical 15772 CFTR Inhibitor II ≥95% 50mg $263 2024-03-01 Buy
Chemenu CM141563 (E)-N''-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98% 10mg $122 2021-12-16 Buy
Chemenu CM141563 (E)-N''-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98% 50mg $467 2021-12-16 Buy
ChemScene CS-2098 GlyH-101 99.00% 5mg $96 2021-12-16 Buy
ChemScene CS-2098 GlyH-101 99.00% 10mg $150 2021-12-16 Buy
ChemScene CS-2098 GlyH-101 99.00% 50mg $624 2021-12-16 Buy
Crysdot CD31002238 GlyH-101 98+% 50mg $697 2021-12-16 Buy
DC Chemicals DC7039 CFTRInhibitorII >98% 100mg $600 2021-12-16 Buy

Properties

Melting point :>300℃ (ethanol )
Density :1.73±0.1 g/cm3(Predicted)
storage temp. := -70C
solubility :DMF:30.0(Max Conc. mg/mL);60.83(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.01(Max Conc. mM)
DMSO:57.58(Max Conc. mg/mL);116.75(Max Conc. mM) form :Yellow solid
pka :5.44±0.45(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 μM). This compound binds to a site at the external pore of CFTR, occluding the pore and rapidly preventing chloride transport. Intraluminal CFTR inhibitor II greatly reduces intestinal fluid secretion induced by cholera toxin. It is effective in cells in culture and also in nasal and intestinal epithelia in vivo.

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