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ChemicalBook >> CAS DataBase List >> GlyH-101

GlyH-101

GlyH-101 price.
  • $18 - $3791
  • Product name: GlyH-101
  • CAS: 328541-79-3
  • MF: C19H15Br2N3O3
  • MW: 493.15
  • EINECS:
  • MDL Number:MFCD01532954
  • Synonyms:(NAPHTHALEN-2-YLAMINO)-ACETIC ACID (3,5-DIBROMO-2,4-DIHYDROXY-BENZYLIDENE)-HYDRAZIDE;GLYH-101;Glycine, N-2-naphthalenyl-, [(3,5-dibroMo-2,4-dihydroxyphenyl)Methylene]hydrazide;N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;N-2-Naphthalenylglycine [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;GlyH 101 N-2-Naphthalenylglycine [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;N-2-Naphthalenylglycine [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide CFTR Inhibitor II;CFTR Inhibitor II, GlyH-101
Price43 Properties Safety Information Description
43 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 25mg
  • 10mM*1mLinDMSO
  • 1mg
  • 50
  • 100.00mg
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  • 50.00mg
  • 250.00mg
  • 10mM(in1mLDMSO)
  • 2mg
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  • 100MG
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00C6CY
  • Product descriptionN'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98%
  • Packaging250mg
  • Price$308
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6CY
  • Product descriptionN'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98%
  • Packaging1g
  • Price$820
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6CY
  • Product descriptionN'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+%
  • Packaging50mg
  • Price$79
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6CY
  • Product descriptionN'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+%
  • Packaging10mg
  • Price$30
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6CY
  • Product descriptionN'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+%
  • Packaging5mg
  • Price$22
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6CY
  • Product descriptionN'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+%
  • Packaging2mg
  • Price$18
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberO32852
  • Product descriptionCFTR Inhibitor II 98%
  • Packaging1G
  • Price$540
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO32852
  • Product descriptionCFTR Inhibitor II 98%
  • Packaging100MG
  • Price$170
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3698AH
  • Product description(Naphthalen-2-ylamino)-aceticacid(3,5-dibromo-2,4-dihydroxy-benzylidene)-hydrazide
  • Packaging1g
  • Price$721
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1087
  • Product descriptionGlyH-101
  • Packaging50mg
  • Price$525
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1087
  • Product descriptionGlyH-101
  • Packaging10mg
  • Price$125
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1087
  • Product descriptionGlyH-101
  • Packaging10mM(in 1mL DMSO)
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1087
  • Product descriptionGlyH-101
  • Packaging10mM(in1mLDMSO)
  • Price$85
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8094
  • Product descriptionGlyH-101 99.05%
  • Packaging25mg
  • Price$425
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberSLK-S8094
  • Product descriptionGlyH-101 99.05%
  • Packaging100mg
  • Price$922
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8094
  • Product descriptionGlyH-101 99.05%
  • Packaging1g
  • Price$3791
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C6CY N'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98% 250mg $308 2026-05-28 Buy
aablocks AA00C6CY N'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98% 1g $820 2026-05-28 Buy
aablocks AA00C6CY N'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+% 50mg $79 2026-05-28 Buy
aablocks AA00C6CY N'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+% 10mg $30 2026-05-28 Buy
aablocks AA00C6CY N'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+% 5mg $22 2026-05-28 Buy
aablocks AA00C6CY N'-(3,5-Dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide 98+% 2mg $18 2026-05-28 Buy
ACHEMBLOCK O32852 CFTR Inhibitor II 98% 1G $540 2026-05-27 Buy
ACHEMBLOCK O32852 CFTR Inhibitor II 98% 100MG $170 2026-05-27 Buy
AK Scientific 3698AH (Naphthalen-2-ylamino)-aceticacid(3,5-dibromo-2,4-dihydroxy-benzylidene)-hydrazide 1g $721 2021-12-16 Buy
ApexBio Technology B1087 GlyH-101 50mg $525 2026-05-06 Buy
ApexBio Technology B1087 GlyH-101 10mg $125 2026-05-06 Buy
ApexBio Technology B1087 GlyH-101 10mM(in 1mL DMSO) $85 2021-12-16 Buy
ApexBio Technology B1087 GlyH-101 10mM(in1mLDMSO) $85 2026-05-06 Buy
Arctom SLK-S8094 GlyH-101 99.05% 25mg $425 2026-05-26 Buy
Arctom SLK-S8094 GlyH-101 99.05% 100mg $922 2026-05-26 Buy
Arctom SLK-S8094 GlyH-101 99.05% 1g $3791 2026-05-26 Buy
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Properties

Melting point :>300℃ (ethanol )
Density :1.73±0.1 g/cm3(Predicted)
storage temp. := -70C
solubility :DMF:30.0(Max Conc. mg/mL);60.83(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.01(Max Conc. mM)
DMSO:57.58(Max Conc. mg/mL);116.75(Max Conc. mM) form :Yellow solid
pka :5.44±0.45(Predicted)
color :Light yellow to yellow
InChI :1S/C19H15Br2N3O3/c20-15-8-13(18(26)17(21)19(15)27)9-23-24-16(25)10-22-14-6-5-11-3-1-2-4-12(11)7-14/h1-9,22,26-27H,10H2,(H,24,25)/b23-9+
InChIKey :RMBDLOATEPYBSI-NUGSKGIGSA-N
SMILES :Brc1c(c(cc(c1O)\C=N\NC(=O)CNc2cc3c(cc2)cccc3)Br)O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 μM). This compound binds to a site at the external pore of CFTR, occluding the pore and rapidly preventing chloride transport. Intraluminal CFTR inhibitor II greatly reduces intestinal fluid secretion induced by cholera toxin. It is effective in cells in culture and also in nasal and intestinal epithelia in vivo.

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