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ChemicalBook >> CAS DataBase List >> HS-173

HS-173

HS-173 price.
  • $26 - $2880
  • Product name: HS-173
  • CAS: 1276110-06-5
  • MF: C21H18N4O4S
  • MW: 422.46
  • EINECS:
  • MDL Number:MFCD28023584
  • Synonyms:ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate;6-[5-[(Phenylsulfonyl)amino]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester HS-173;HS-173;6-[5-[(Phenylsulfonyl)amino]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester;HS 173;HS173;CS-1007;HS-173, 98%, a novel PI3K inhibitor;Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-, ethyl ester
Price51 Properties Safety Information Description
51 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Synthonix
  • TRC
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM(in1mLDMSO)
  • 1mg
  • 5.00mg
  • 10mM*1mLinDMSO(Solution)
  • 2mg
  • 5mg
  • 10mg
  • 10.00mg
  • 25mg
  • 25.00mg
  • 50mg
  • 100mg
  • 200mg
  • 250MG
  • 0.5g
  • 1000mg
  • 1G
  • 5G
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99
  • Packaging2mg
  • Price$44
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99%
  • Packaging5mg
  • Price$56
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99%
  • Packaging1mg
  • Price$26
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99
  • Packaging10mg
  • Price$80
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99
  • Packaging25mg
  • Price$130
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99
  • Packaging50mg
  • Price$199
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99
  • Packaging100mg
  • Price$284
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000X58
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99
  • Packaging200mg
  • Price$399
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65506
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate 98%
  • Packaging1G
  • Price$720
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65506
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate 98%
  • Packaging5G
  • Price$2880
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65506
  • Product descriptionethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate 98%
  • Packaging250MG
  • Price$275
  • Updated2026-05-27
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  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging50mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging25mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4492
  • Product descriptionHS-173
  • Packaging10mM(in1mLDMSO)
  • Price$83
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99 2mg $44 2026-05-25 Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99% 5mg $56 2026-05-25 Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99% 1mg $26 2026-05-25 Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99 10mg $80 2026-05-25 Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99 25mg $130 2026-05-25 Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99 50mg $199 2026-05-25 Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99 100mg $284 2026-05-25 Buy
aablocks AA000X58 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate 99 200mg $399 2026-05-25 Buy
ACHEMBLOCK Q65506 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate 98% 1G $720 2026-05-27 Buy
ACHEMBLOCK Q65506 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate 98% 5G $2880 2026-05-27 Buy
ACHEMBLOCK Q65506 ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate 98% 250MG $275 2026-05-27 Buy
Ambeed A336342 HS-173 97% 50mg $145 2021-12-16 Buy
Ambeed A336342 HS-173 97% 5mg $65 2021-12-16 Buy
Ambeed A336342 HS-173 97% 10mg $85 2021-12-16 Buy
Ambeed A336342 HS-173 97% 25mg $111 2021-12-16 Buy
ApexBio Technology B4492 HS-173 10mM(in1mLDMSO) $83 2026-05-06 Buy
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Properties

Melting point :>193°C (dec.)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly)
pka :6.84±0.40(Predicted)
form :Solid
color :Grey to Brown
InChI :InChI=1S/C21H18N4O4S/c1-2-29-21(26)19-13-23-20-9-8-15(14-25(19)20)16-10-17(12-22-11-16)24-30(27,28)18-6-4-3-5-7-18/h3-14,24H,2H2,1H3
InChIKey :SEKOTFCHZNXZMM-UHFFFAOYSA-N
SMILES :C12=NC=C(C(OCC)=O)N1C=C(C1=CC(NS(C3=CC=CC=C3)(=O)=O)=CN=C1)C=C2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

HS-173 is an imidazopyridine analog that acts as a PI3Kα inhibitor with an IC50 value of 0.8 nM. It demonstrates antiproliferative activity in T47D, SK-BR-3, and MCF-7 cells with IC50 values of 0.6, 1.5, and 7.8 μM, respectively. HS-173 is reported to induce apoptosis by arresting the cell cycle at the G2/M phase and by activating caspases. It has also been shown to block VEGF-induced angiogenesis both in vitro and in vivo.

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Suppliers and manufacturers

Beijing LAL Pharmaceutical Co., Ltd. Shanghai Boyle Chemical Co., Ltd. Dalian Meilun Biotech Co., Ltd. MedChemexpress LLC AdooQ BioScience, LLC ShangHai Caerulum Pharma Discovery Co., Ltd. AdooQ Bioscience CHINA Credit Asia Chemical Co., Ltd. LETOPHARM LIMITED Shanghai Lollane Biological Technology Co.,Ltd.