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ChemicalBook >> CAS DataBase List >> IC86621

IC86621

IC86621 price.
  • $45 - $3761
  • Product name: IC86621
  • CAS: 404009-40-1
  • MF: C12H15NO3
  • MW: 221.25
  • EINECS:
  • MDL Number:MFCD07370140
  • Synonyms:1-(2-hydroxy-4-Morpholinophenyl)ethanone;IC86621 CAS#: 404009-40-1;DNA-PK Inhibitor III - CAS 404009-40-1 - Calbiochem;IC 86621 (IC86621);Ethanone, 1-[2-hydroxy-4-(4-morpholinyl)phenyl]-;1-(2-Hydroxy-4-morpholinophenyl)ethan-1-one;ATP,Buchwald-Hartwig amination,Inhibitor,IC-86621,IC86621,IC 86621,DSB,antitumor,inhibit,Apoptosis,Fries rearrangement,DNA-dependent protein kinase,DNA-PK;1-(2-Hydroxy-4-morpholinophenyl)ethan-1-one , IC 86621
Price47 Properties Safety Information Description
47 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • AstaTech
  • AvaChem
  • Chemenu
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  • ChemScene
  • Crysdot
  • Sigma-Aldrich
  • TRC
  • Usbiological
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  • 0.1G
  • 100mg
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  • 250MG
  • 500mg
  • 1G
  • 5g
  • Manufactureraablocks
  • Product numberAA00CKPS
  • Product description1-(2-Hydroxy-4-morpholinophenyl)ethanone 95
  • Packaging5mg
  • Price$46
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00CKPS
  • Product description1-(2-Hydroxy-4-morpholinophenyl)ethanone 95
  • Packaging10mg
  • Price$57
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00CKPS
  • Product description1-(2-Hydroxy-4-morpholinophenyl)ethanone 95
  • Packaging25mg
  • Price$81
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00CKPS
  • Product description1-(2-Hydroxy-4-morpholinophenyl)ethanone 95
  • Packaging50mg
  • Price$110
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00CKPS
  • Product description1-(2-Hydroxy-4-morpholinophenyl)ethanone 95
  • Packaging100mg
  • Price$152
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00CKPS
  • Product description1-(2-Hydroxy-4-morpholinophenyl)ethanone 95%
  • Packaging5g
  • Price$1000
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX186547
  • Product description1-(2-hydroxy-4-morpholinophenyl)ethanone 95%
  • Packaging1G
  • Price$1140
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberX186547
  • Product description1-(2-hydroxy-4-morpholinophenyl)ethanone 95%
  • Packaging250MG
  • Price$380
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number4512AH
  • Product description1-(2-Hydroxy-4-morpholinophenyl)ethanone
  • Packaging250mg
  • Price$428
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0073228
  • Product description1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95.00%
  • Packaging100MG
  • Price$824.19
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberHY-100707
  • Product descriptionIC 86621 99.06%
  • Packaging10mg
  • Price$91
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-100707
  • Product descriptionIC 86621 99.06%
  • Packaging5mg
  • Price$65
  • Updated2026-05-26
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  • ManufacturerAstaTech
  • Product numberAR2783
  • Product description1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95%
  • Packaging25MG
  • Price$69
  • Updated2026-04-30
  • Buy
  • ManufacturerAstaTech
  • Product numberAR2783
  • Product description1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95%
  • Packaging0.1G
  • Price$164
  • Updated2026-04-30
  • Buy
  • ManufacturerAstaTech
  • Product numberAR2783
  • Product description1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95%
  • Packaging0.25G
  • Price$347
  • Updated2026-04-30
  • Buy
  • ManufacturerAstaTech
  • Product numberAR2783
  • Product description1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95%
  • Packaging5G
  • Price$877
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00CKPS 1-(2-Hydroxy-4-morpholinophenyl)ethanone 95 5mg $46 2026-05-28 Buy
aablocks AA00CKPS 1-(2-Hydroxy-4-morpholinophenyl)ethanone 95 10mg $57 2026-05-28 Buy
aablocks AA00CKPS 1-(2-Hydroxy-4-morpholinophenyl)ethanone 95 25mg $81 2026-05-28 Buy
aablocks AA00CKPS 1-(2-Hydroxy-4-morpholinophenyl)ethanone 95 50mg $110 2026-05-28 Buy
aablocks AA00CKPS 1-(2-Hydroxy-4-morpholinophenyl)ethanone 95 100mg $152 2026-05-28 Buy
aablocks AA00CKPS 1-(2-Hydroxy-4-morpholinophenyl)ethanone 95% 5g $1000 2026-05-28 Buy
ACHEMBLOCK X186547 1-(2-hydroxy-4-morpholinophenyl)ethanone 95% 1G $1140 2026-05-27 Buy
ACHEMBLOCK X186547 1-(2-hydroxy-4-morpholinophenyl)ethanone 95% 250MG $380 2026-05-27 Buy
AK Scientific 4512AH 1-(2-Hydroxy-4-morpholinophenyl)ethanone 250mg $428 2021-12-16 Buy
American Custom Chemicals Corporation CHM0073228 1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95.00% 100MG $824.19 2021-12-16 Buy
Arctom HY-100707 IC 86621 99.06% 10mg $91 2026-05-26 Buy
Arctom HY-100707 IC 86621 99.06% 5mg $65 2026-05-26 Buy
AstaTech AR2783 1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95% 25MG $69 2026-04-30 Buy
AstaTech AR2783 1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95% 0.1G $164 2026-04-30 Buy
AstaTech AR2783 1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95% 0.25G $347 2026-04-30 Buy
AstaTech AR2783 1-(2-HYDROXY-4-MORPHOLINOPHENYL)ETHANONE 95% 5G $877 2026-04-30 Buy
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Properties

Melting point :98-100.3 °C
Boiling point :425.5±45.0 °C(Predicted)
Density :1.210±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 15 mg/mL
pka :10.47±0.10(Predicted)
form :solid
color :off-white
InChI :1S/C12H15NO3/c1-9(14)11-3-2-10(8-12(11)15)13-4-6-16-7-5-13/h2-3,8,15H,4-7H2,1H3
InChIKey :YHKSBKQXCWHTQL-UHFFFAOYSA-N

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

DNA-PK Inhibitor III is a cell-permeable aryl-morpholino compound that is potent, selective, and an ATP-competitive inhibitor of DNA-PK (IC50= 120 nM) and PI 3-Kinase catalytic subunit p110β (IC50= 135 nM). Inhibits DNA-PK-mediated cellular DNA DSB (double strand break) repair (EC50= 68 μM) and enhances DSB-induced antitumor activity in vitro, while exhibiting no cytotoxic effects (up to 50 μM) in the absence of DSBs. Also inhibits PI 3K p110α, p110γ, and p110δ only at much higher concentrations (IC50= 1.4 μM, 880 nM, and 1.0 μM, respectively) and exhibits no effect against a panel of several other kinases, including, Cdk2, Src, PKA, PKC, Chk1, CK1, ATM, and FKBP12, even at concentrations as high as 100 μM.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
IC 86621
$32.00
IC 86621 CAS:404009-40-1
ATK CHEMICAL COMPANY LIMITED
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
Amadis Chemical Company Limited VDM Biochemicals BOC Sciences Sigma-Aldrich SanoChem (Chengdu) Tech. Co., Ltd. Shanghai EFE Biological Technology Co., Ltd.