ICA 069673
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- $19 - $1529.85
- Product name: ICA 069673
- CAS: 582323-16-8
- MF: C11H6ClF2N3O
- MW: 269.63
- EINECS:
- MDL Number:MFCD20926351
- Synonyms:ICA 069673;N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide;ICA069673;ICA-069673;Benzamide, N-(2-chloro-5-pyrimidinyl)-3,4-difluoro-;ICA-069673 >=98% (HPLC);Potassium Channel,ICA 069673,ICA-069673,KcsA,inhibit,Inhibitor;N-(2-Chloropyrimidin-5-yl)-3,4-difluorobenzamide;ICA-069673, 10 mM in DMSO
43 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 25
- 1mg
- 5mg
- 5
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA00EJSP
- Product descriptionICA 069673 98%
- Packaging1mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EJSP
- Product descriptionICA 069673 98%
- Packaging5mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EJSP
- Product descriptionICA 069673 98%
- Packaging10mg
- Price$83
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EJSP
- Product descriptionICA 069673 98%
- Packaging50mg
- Price$318
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EJSP
- Product descriptionICA 069673 98%
- Packaging25mg
- Price$181
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EJSP
- Product descriptionICA 069673 98%
- Packaging100mg
- Price$572
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238599
- Product descriptionICA-069673 98%
- Packaging100MG
- Price$330
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238599
- Product descriptionICA-069673 98%
- Packaging25MG
- Price$125
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number5824CR
- Product descriptionN-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide
- Packaging25mg
- Price$502
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010327
- Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
- Packaging10MG
- Price$669.9
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010327
- Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
- Packaging50MG
- Price$1004.85
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010327
- Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
- Packaging1G
- Price$1529.85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7640
- Product descriptionICA 069673
- Packaging25mg
- Price$366
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7640
- Product descriptionICA 069673
- Packaging10mg
- Price$173
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7640
- Product descriptionICA 069673
- Packaging100mg
- Price$1170
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7640
- Product descriptionICA 069673
- Packaging50mg
- Price$655
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00EJSP | ICA 069673 98% | 1mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00EJSP | ICA 069673 98% | 5mg | $49 | 2026-05-28 | Buy |
| aablocks | AA00EJSP | ICA 069673 98% | 10mg | $83 | 2026-05-28 | Buy |
| aablocks | AA00EJSP | ICA 069673 98% | 50mg | $318 | 2026-05-28 | Buy |
| aablocks | AA00EJSP | ICA 069673 98% | 25mg | $181 | 2026-05-28 | Buy |
| aablocks | AA00EJSP | ICA 069673 98% | 100mg | $572 | 2026-05-28 | Buy |
| ACHEMBLOCK | Z238599 | ICA-069673 98% | 100MG | $330 | 2026-05-27 | Buy |
| ACHEMBLOCK | Z238599 | ICA-069673 98% | 25MG | $125 | 2026-05-27 | Buy |
| AK Scientific | 5824CR | N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide | 25mg | $502 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010327 | N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% | 10MG | $669.9 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010327 | N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% | 50MG | $1004.85 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010327 | N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% | 1G | $1529.85 | 2021-12-16 | Buy |
| ApexBio Technology | B7640 | ICA 069673 | 25mg | $366 | 2026-05-06 | Buy |
| ApexBio Technology | B7640 | ICA 069673 | 10mg | $173 | 2026-05-06 | Buy |
| ApexBio Technology | B7640 | ICA 069673 | 100mg | $1170 | 2026-05-06 | Buy |
| ApexBio Technology | B7640 | ICA 069673 | 50mg | $655 | 2026-05-06 | Buy |
Properties
Boiling point :358.9±37.0 °C(Predicted)
Density :1.539±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DNF:30.0(Max Conc. mg/mL);111.26(Max Conc. mM)
DMSO:36.24(Max Conc. mg/mL);134.4(Max Conc. mM)
Ethanol:30.25(Max Conc. mg/mL);112.18(Max Conc. mM) form :Powder
pka :9.47±0.70(Predicted)
color :White to off-white
InChI :1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
InChIKey :IIBSHMFXVWTQSJ-UHFFFAOYSA-N
SMILES :O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2
Density :1.539±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DNF:30.0(Max Conc. mg/mL);111.26(Max Conc. mM)
DMSO:36.24(Max Conc. mg/mL);134.4(Max Conc. mM)
Ethanol:30.25(Max Conc. mg/mL);112.18(Max Conc. mM) form :Powder
pka :9.47±0.70(Predicted)
color :White to off-white
InChI :1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
InChIKey :IIBSHMFXVWTQSJ-UHFFFAOYSA-N
SMILES :O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2
Safety Information
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Description
ICA 069673 is a heteromeric Kv7 channel activator. It is selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50s = 0.69 and 14.3 μM, respectively) and also activates Kv7.4, Kv7.5, and heteromeric Kv7.4/7.5 channels in a dose-dependent manner. ICA 069673 has no activity against hERG, Nav1.5, and Kv7.1 cardiac ion channels (IC50s = >30 μM). Oral administration of ICA 069673 increases latency to first tonic-clonic seizure in the rat maximal electroshock and pentylentetrazol-induced seizure models (ED50s = 1.5 and <1 mg/kg, respectively). Formulations containing ICA 069673 are under clinical investigation for the treatment of epilepsy.Related product price
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Suppliers and manufacturers
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