IPI 145
|
- $18 - $2550
- Product name: IPI 145
- CAS: 1201438-56-3
- MF: C22H17ClN6O
- MW: 416.86
- EINECS:200-256-5
- MDL Number:MFCD15144635
- Synonyms:IPI-145;IPI-145 (INK-1197);IPI-145 INK197;8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone;IPI-145, >=98%;Duvelisib (IPI-145, INK1197);DUVELISIB (IPI-145);1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-
61 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 500μg
- 25mg
- 10mM*1mLinDMSO(Solution)
- 200mg
- 10mM*1mLinDMSO
- 250mg
- 500mg
- 2g
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 20mg
- 10mM(in1mLDMSO)
- 50mg
- 100mg
- 1g
- Manufactureraablocks
- Product numberAA000QBA
- Product descriptionDuvelisib ≥98%
- Packaging5mg
- Price$54
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000QBA
- Product descriptionDuvelisib 99%
- Packaging1mg
- Price$18
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000QBA
- Product descriptionDuvelisib
- Packaging10mg
- Price$88
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000QBA
- Product descriptionDuvelisib
- Packaging50mg
- Price$147
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000QBA
- Product descriptionDuvelisib
- Packaging100mg
- Price$225
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000QBA
- Product descriptionDuvelisib 95%
- Packaging1g
- Price$1690
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8738
- Product descriptionDuvelisib 98%
- Packaging1G
- Price$595
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8738
- Product descriptionDuvelisib 98%
- Packaging100MG
- Price$150
- Updated2026-05-25
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M005
- Product descriptionIPI-145 ≥95%
- Packaging5mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M005
- Product descriptionIPI-145 ≥95%
- Packaging5mg
- Price$178
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M010
- Product descriptionIPI-145 ≥95%
- Packaging10mg
- Price$297
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M001
- Product descriptionIPI-145 ≥95%
- Packaging1mg
- Price$113
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M050
- Product descriptionIPI-145 ≥95%
- Packaging50mg
- Price$1004
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M050
- Product descriptionIPI-145 ≥95%
- Packaging50mg
- Price$1004
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberSYN1175
- Product descriptionIPI145
- Packaging100mg
- Price$1660
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1720
- Product descriptionDuvelisib (IPI-145, INK1197)
- Packaging10mg
- Price$88
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000QBA | Duvelisib ≥98% | 5mg | $54 | 2026-05-25 | Buy |
| aablocks | AA000QBA | Duvelisib 99% | 1mg | $18 | 2026-05-25 | Buy |
| aablocks | AA000QBA | Duvelisib | 10mg | $88 | 2026-05-25 | Buy |
| aablocks | AA000QBA | Duvelisib | 50mg | $147 | 2026-05-25 | Buy |
| aablocks | AA000QBA | Duvelisib | 100mg | $225 | 2026-05-25 | Buy |
| aablocks | AA000QBA | Duvelisib 95% | 1g | $1690 | 2026-05-25 | Buy |
| ACHEMBLOCK | H-8738 | Duvelisib 98% | 1G | $595 | 2026-05-25 | Buy |
| ACHEMBLOCK | H-8738 | Duvelisib 98% | 100MG | $150 | 2026-05-25 | Buy |
| Adipogen Life Sciences | SYN-1175-M005 | IPI-145 ≥95% | 5mg | $178 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1175-M005 | IPI-145 ≥95% | 5mg | $178 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1175-M010 | IPI-145 ≥95% | 10mg | $297 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1175-M001 | IPI-145 ≥95% | 1mg | $113 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1175-M050 | IPI-145 ≥95% | 50mg | $1004 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1175-M050 | IPI-145 ≥95% | 50mg | $1004 | 2026-05-06 | Buy |
| AK Scientific | SYN1175 | IPI145 | 100mg | $1660 | 2021-12-16 | Buy |
| ApexBio Technology | A1720 | Duvelisib (IPI-145, INK1197) | 10mg | $88 | 2026-05-06 | Buy |
Properties
Melting point :205-206o C
Boiling point :757.8±60.0 °C(Predicted)
Density :1.474±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White solid.
pka :10.05±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1
InChIKey :SJVQHLPISAIATJ-ZDUSSCGKSA-N
SMILES :C1(=O)C2=C(C=CC=C2Cl)C=C([C@@H](NC2=C3C(=NC=N2)NC=N3)C)N1C1=CC=CC=C1
Boiling point :757.8±60.0 °C(Predicted)
Density :1.474±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White solid.
pka :10.05±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1
InChIKey :SJVQHLPISAIATJ-ZDUSSCGKSA-N
SMILES :C1(=O)C2=C(C=CC=C2Cl)C=C([C@@H](NC2=C3C(=NC=N2)NC=N3)C)N1C1=CC=CC=C1
Safety Information
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| Signal word: | Danger | ||||||||||||||||||||||||||||||||
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Description
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kγ and PI3Kδ (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kγ and PI3Kδ are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and adjuvant-induced arthritis, ovalbumin-induced asthma, and systemic lupus erythematosus animal models. It also has potential applications in immunotherapy and in certain cancers.More related product prices
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