L-THREO-SPHINGOSINE
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- $122 - $1990
- Product name: L-THREO-SPHINGOSINE
- CAS: 25695-95-8
- MF: C18H37NO2
- MW: 299.49
- EINECS:
- MDL Number:MFCD02259136
- Synonyms:(2S,3S,4E)-2-AMINO-1,3-OCTADEC-4-ENEDIOL;(2S,3S,4E)-2-AMINOOCTADEC-4-ENE-1,3-DIOL;L-THREO-SPHINGOSINE;L-THREO-SPHINGOSINE, C18 CHAIN;(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol;L-threo-C18-Sphingosine;threo-(2S,3S)-Sphingosine;L-THREO-SPHINGOSINE C-18
6 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
Package
- 5mg
- 10mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number1366AH
- Product description2S-Amino-4E-octadecene-1,3S-diol
- Packaging100mg
- Price$1990
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4717
- Product descriptionL-threo-SphingosineC-18
- Packaging10mg
- Price$264
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) >98%
- Packaging5mg
- Price$122
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) >98%
- Packaging10mg
- Price$232
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) >98%
- Packaging50mg
- Price$971
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010541
- Product descriptionL-threo-Sphingosine (d18:1) >98%
- Packaging100mg
- Price$1698
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1366AH | 2S-Amino-4E-octadecene-1,3S-diol | 100mg | $1990 | 2021-12-16 | Buy |
| ApexBio Technology | C4717 | L-threo-SphingosineC-18 | 10mg | $264 | 2021-12-16 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) >98% | 5mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) >98% | 10mg | $232 | 2024-03-01 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) >98% | 50mg | $971 | 2024-03-01 | Buy |
| Cayman Chemical | 10010541 | L-threo-Sphingosine (d18:1) >98% | 100mg | $1698 | 2024-03-01 | Buy |
Properties
Melting point :86-88 °C
Boiling point :445.9±45.0 °C(Predicted)
Density :0.939±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Ethanol: 0.25 mg/ml
form :A crystalline solid
pka :11.80±0.45(Predicted)
Boiling point :445.9±45.0 °C(Predicted)
Density :0.939±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Ethanol: 0.25 mg/ml
form :A crystalline solid
pka :11.80±0.45(Predicted)
Safety Information
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Description
L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits PKC (protein kinase C) in mixed micelle assays with 50% inhibition at 2.2 mol % making it a slightly more stronger inhibitor compared to D-erythro-sphingosine (50% inhibition at 2.8 mol %) or other analogs of shorter alkyl chain length. Addition of L-threo-Sphingosine C-18 to primary cultured cerebellar cells does not decrease serine palmitoyltransferase (SPT) activity, the rate-limiting enzyme in ceramide biosynthesis, whereas under similar conditions D-erythro-sphingosine inhibits SPT activity. Sphingosines are long-chain base precursors of cellular sphingolipids and are used directly in the synthesis of ceramide. Sphingosine can exist in four stereoisomers, however only D-erythro-sphingosine occurs naturally.More related product prices
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$122-1990