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ChemicalBook >> CAS DataBase List >> LMK-235

LMK-235

LMK-235 price.
  • $37 - $2245.7
  • Product name: LMK-235
  • CAS: 1418033-25-6
  • MF: C15H22N2O4
  • MW: 294.35
  • EINECS:808-770-7
  • MDL Number:MFCD26522892
  • Synonyms:N-[[6-(Hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-benzamide;N-[[6-(Hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethylbenzamide LMK-235;LMK-235;CS-1820;LMK235; LMK 235;Benzamide, N-[[6-(hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-
Price35 Properties Safety Information Description
35 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10
  • 1mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 50
  • 10mM(in 1mL DMSO)
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2520AH
  • Product descriptionN-[[6-(Hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-benzamide
  • Packaging10mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA135784
  • Product descriptionLMK-235 98+%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA135784
  • Product descriptionLMK-235 98+%
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA135784
  • Product descriptionLMK-235 98+%
  • Packaging50mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4494
  • Product descriptionLMK235
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4494
  • Product descriptionLMK235
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4494
  • Product descriptionLMK235
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146208
  • Product descriptionLMK-235 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146208
  • Product descriptionLMK-235 >98%
  • Packaging250mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146208
  • Product descriptionLMK-235 >98%
  • Packaging1g
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH90205
  • Product descriptionLMK 235
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH90205
  • Product descriptionLMK 235
  • Packaging50mg
  • Price$297.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14969
  • Product descriptionLMK 235 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14969
  • Product descriptionLMK 235 ≥98%
  • Packaging5mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14969
  • Product descriptionLMK 235 ≥98%
  • Packaging10mg
  • Price$127
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14969
  • Product descriptionLMK 235 ≥98%
  • Packaging25mg
  • Price$266
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2520AH N-[[6-(Hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-benzamide 10mg $164 2021-12-16 Buy
Ambeed A135784 LMK-235 98+% 5mg $50 2021-12-16 Buy
Ambeed A135784 LMK-235 98+% 10mg $65 2021-12-16 Buy
Ambeed A135784 LMK-235 98+% 50mg $110 2021-12-16 Buy
ApexBio Technology A4494 LMK235 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A4494 LMK235 10mg $80 2021-12-16 Buy
ApexBio Technology A4494 LMK235 50mg $250 2021-12-16 Buy
Biorbyt Ltd orb146208 LMK-235 >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb146208 LMK-235 >98% 250mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb146208 LMK-235 >98% 1g $2245.7 2021-12-16 Buy
Biosynth Carbosynth FH90205 LMK 235 10mg $85 2021-12-16 Buy
Biosynth Carbosynth FH90205 LMK 235 50mg $297.5 2021-12-16 Buy
Cayman Chemical 14969 LMK 235 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 14969 LMK 235 ≥98% 5mg $72 2024-03-01 Buy
Cayman Chemical 14969 LMK 235 ≥98% 10mg $127 2024-03-01 Buy
Cayman Chemical 14969 LMK 235 ≥98% 25mg $266 2024-03-01 Buy
Next Last

Properties

Melting point :135-138°C
Density :1.155±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :9.46±0.20(Predicted)
color :white to beige
InChIKey :VRYZCEONIWEUAV-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues, which commonly results in chromatin condensation and transcriptional repression. LMK 235 is an HDAC inhibitor that selectively targets HDACs 4 and 5 (IC50s = 12 and 4 nM, respectively) over other HDACs (IC50s = 56, 320, 850, 880, and 1,280 for HDACs 6, 1, 11, 2, and 8, respectively). It displays enhanced cytotoxic effects against human cancer cell lines, compared to SAHA or trichostatin A . LMK 235 and derivatives inhibit the growth of the malarial parasite P. falciparum at multiple life cycle stages at nanomolar concentrations.

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