YM155
|
- $21 - $2395.3
- Product name: YM155
- CAS: 781661-94-7
- MF: C20H19BrN4O3
- MW: 443.29386
- EINECS:-0
- MDL Number:MFCD11983133
- Synonyms:YM155;4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide;SepantroniuM broMide(YM155,YM-155);Sepantronium Bromide (YM155);1H-Naphth[2,3-d]imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-, bromide (1:1);4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide YM 155;YM 155 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide;YM155 (SepantroniuM BroMide)
75 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 10mM*1mLinDMSO
- 10mM(in 1mL DMSO)
- EvaluationSample
- 5g
- 10 mg
- 10
- 1 unit
- 50 mg
- 10mM(in1mLDMSO)
- 1unit
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 250mg
- 500MG
- 1g
- Manufactureraablocks
- Product numberAA0036JM
- Product description1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98%
- Packaging5mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036JM
- Product description1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98%
- Packaging10mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036JM
- Product description1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98%
- Packaging50mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036JM
- Product description1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98%
- Packaging100mg
- Price$127
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberT98095
- Product description3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide 97%
- Packaging25MG
- Price$180
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT98095
- Product description3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide 97%
- Packaging100MG
- Price$525
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT98095
- Product description3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide 97%
- Packaging500MG
- Price$1175
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5758
- Product descriptionYM155
- Packaging100mg
- Price$931
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA307284
- Product descriptionYM-155 98+%
- Packaging1g
- Price$928
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA307284
- Product descriptionSepantronium bromide 98%
- Packaging250mg
- Price$270
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA307284
- Product descriptionSepantronium bromide 98%
- Packaging100mg
- Price$160
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA307284
- Product descriptionSepantronium bromide 98%
- Packaging5mg
- Price$27
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA307284
- Product descriptionSepantronium bromide 98%
- Packaging10mg
- Price$38
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA307284
- Product descriptionSepantronium bromide 98%
- Packaging50mg
- Price$103
- Updated2026-06-05
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004446
- Product descriptionYM-155 95.00%
- Packaging5MG
- Price$526
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004446
- Product descriptionYM-155 95.00%
- Packaging10MG
- Price$594.8
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0036JM | 1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98% | 5mg | $22 | 2026-05-28 | Buy |
| aablocks | AA0036JM | 1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98% | 10mg | $31 | 2026-05-28 | Buy |
| aablocks | AA0036JM | 1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98% | 50mg | $82 | 2026-05-28 | Buy |
| aablocks | AA0036JM | 1-(2-Methoxyethyl)-2-Methyl-4,9-Dioxo-3-(Pyrazin-2-Ylmethyl)-4,9-Dihydro-1H-Naphtho[2,3-d]Imidazol-3-Ium Bromide 98% | 100mg | $127 | 2026-05-28 | Buy |
| ACHEMBLOCK | T98095 | 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide 97% | 25MG | $180 | 2026-05-27 | Buy |
| ACHEMBLOCK | T98095 | 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide 97% | 100MG | $525 | 2026-05-27 | Buy |
| ACHEMBLOCK | T98095 | 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide 97% | 500MG | $1175 | 2026-05-27 | Buy |
| AK Scientific | SYN5758 | YM155 | 100mg | $931 | 2021-12-16 | Buy |
| Ambeed | A307284 | YM-155 98+% | 1g | $928 | 2021-12-16 | Buy |
| Ambeed | A307284 | Sepantronium bromide 98% | 250mg | $270 | 2026-06-05 | Buy |
| Ambeed | A307284 | Sepantronium bromide 98% | 100mg | $160 | 2026-06-05 | Buy |
| Ambeed | A307284 | Sepantronium bromide 98% | 5mg | $27 | 2026-06-05 | Buy |
| Ambeed | A307284 | Sepantronium bromide 98% | 10mg | $38 | 2026-06-05 | Buy |
| Ambeed | A307284 | Sepantronium bromide 98% | 50mg | $103 | 2026-06-05 | Buy |
| American Custom Chemicals Corporation | INB0004446 | YM-155 95.00% | 5MG | $526 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004446 | YM-155 95.00% | 10MG | $594.8 | 2021-12-16 | Buy |
Properties
Melting point :>180°C (dec.)
storage temp. :-20°
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
color :Tan to yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C20H19N4O3.BrH/c1-13-23(9-10-27-2)17-18(24(13)12-14-11-21-7-8-22-14)20(26)16-6-4-3-5-15(16)19(17)25;/h3-8,11H,9-10,12H2,1-2H3;1H/q+1;/p-1
InChIKey :QBIYUDDJPRGKNJ-UHFFFAOYSA-M
SMILES :c12[n+](Cc3nccnc3)c(C)[n](CCOC)c1C(=O)c1ccccc1C2=O.[Br-]
storage temp. :-20°
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
color :Tan to yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C20H19N4O3.BrH/c1-13-23(9-10-27-2)17-18(24(13)12-14-11-21-7-8-22-14)20(26)16-6-4-3-5-15(16)19(17)25;/h3-8,11H,9-10,12H2,1-2H3;1H/q+1;/p-1
InChIKey :QBIYUDDJPRGKNJ-UHFFFAOYSA-M
SMILES :c12[n+](Cc3nccnc3)c(C)[n](CCOC)c1C(=O)c1ccccc1C2=O.[Br-]
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Survivin, a member of the inhibitor of apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in many types of cancer. YM-155 is a novel small molecule that suppresses transactivation of survivin through direct binding to its promoter. It selectively suppresses expression of survivin and induces apoptosis in p53-deficient cancer cells in vitro at 10 nM. At concentrations up to 100 nM, YM-155 has little effect on expression levels of other IAP- or Bcl-2-related proteins. YM-155 exerts anti-tumor effects in various in vivo cancer models, including prostate, pancreatic, and lung cancer.Related product price
-
252917-06-9
$28-4401 -
ABT 263
$24-2245.7 -
871700-17-3
$28-4391.1
Suppliers and manufacturers
Zhengzhou HSH Science & Technology Co., Ltd.
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.
Chembest Research Laboratories Limited
Chemsky (shanghai) International Co.,Ltd
Jinan Trio PharmaTech Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
NCE Biomedical Co.,Ltd.
China Kouting Group Limited
Haoyuan Chemexpress Co., Ltd.