Welcome to chemicalbook!

010-86108875

18162-48-6 872-50-4 Methylene Chloride naphthalene THF Titanium Dioxide

Structure Search

RFQ

Try our best to find the right business for you.

Messages

Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> LOXO-101

LOXO-101

$30 - $2841
Product name: LOXO-101
CAS: 1223403-58-4
MF: C21H22F2N6O2
MW: 428.44
EINECS:
MDL Number:MFCD28902192
Synonyms:LOXO-101;(R)-N-(5-((S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide;ARRY 470;(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide;LOXO-101 (ARRY-470);CS-2322;LOXO101;LOXO 101; LOXO-101 Larotrectinib

Price54 Properties Safety Information Description

54 prices

Selected condition：

Brand

ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
AvaChem
Biorbyt Ltd
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
TRC
Usbiological

Package

10mM(1mLinDMSO)
1mg
5MG
10mg
10.00mg
25MG
25.00mg
50.00mg
50mg
100MG
250mg
1G
5G

ManufacturerACHEMBLOCK
Product numberH-8992
Product description(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide 97%
Packaging5MG
Price$30
Updated2021-12-16
Buy

ManufacturerACHEMBLOCK
Product numberH-8992
Product descriptionLOXO-101 98%
Packaging5MG
Price$30
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberH-8992
Product descriptionLOXO-101 98%
Packaging25MG
Price$40
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberH-8992
Product description(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide 97%
Packaging25MG
Price$95
Updated2021-12-16
Buy

ManufacturerACHEMBLOCK
Product numberH-8992
Product descriptionLOXO-101 98%
Packaging100MG
Price$110
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberH-8992
Product descriptionLOXO-101 98%
Packaging1G
Price$495
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberH-8992
Product description(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide 97%
Packaging1G
Price$1150
Updated2021-12-16
Buy

ManufacturerACHEMBLOCK
Product numberH-8992
Product descriptionLOXO-101 98%
Packaging5G
Price$1850
Updated2026-05-25
Buy

ManufacturerAK Scientific
Product number3482DG
Product descriptionLarotrectinib
Packaging50mg
Price$522
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4684
Product descriptionLarotrectinib
Packaging10mg
Price$135
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA4684
Product descriptionLarotrectinib
Packaging5mg
Price$107
Updated2026-05-06
Buy

ManufacturerArctom
Product numberSLK-S5860
Product descriptionLarotrectinib 99.93%
Packaging10mM(1mLinDMSO)
Price$188
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-12866R
Product descriptionLarotrectinib (Standard) 98%
Packaging5mg
Price$219
Updated2026-05-26
Buy

ManufacturerArctom
Product numberSLK-S5860
Product descriptionLarotrectinib 99.93%
Packaging25mg
Price$283
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-12866R
Product descriptionLarotrectinib (Standard) 98%
Packaging10mg
Price$328
Updated2026-05-26
Buy

ManufacturerArctom
Product numberSLK-S5860
Product descriptionLarotrectinib 99.93%
Packaging5mg
Price$140
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
ACHEMBLOCK	H-8992	(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide 97%	5MG	$30	2021-12-16	Buy
ACHEMBLOCK	H-8992	LOXO-101 98%	5MG	$30	2026-05-25	Buy
ACHEMBLOCK	H-8992	LOXO-101 98%	25MG	$40	2026-05-25	Buy
ACHEMBLOCK	H-8992	(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide 97%	25MG	$95	2021-12-16	Buy
ACHEMBLOCK	H-8992	LOXO-101 98%	100MG	$110	2026-05-25	Buy
ACHEMBLOCK	H-8992	LOXO-101 98%	1G	$495	2026-05-25	Buy
ACHEMBLOCK	H-8992	(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide 97%	1G	$1150	2021-12-16	Buy
ACHEMBLOCK	H-8992	LOXO-101 98%	5G	$1850	2026-05-25	Buy
AK Scientific	3482DG	Larotrectinib	50mg	$522	2021-12-16	Buy
ApexBio Technology	A4684	Larotrectinib	10mg	$135	2026-05-06	Buy
ApexBio Technology	A4684	Larotrectinib	5mg	$107	2026-05-06	Buy
Arctom	SLK-S5860	Larotrectinib 99.93%	10mM(1mLinDMSO)	$188	2026-05-26	Buy
Arctom	HY-12866R	Larotrectinib (Standard) 98%	5mg	$219	2026-05-26	Buy
Arctom	SLK-S5860	Larotrectinib 99.93%	25mg	$283	2026-05-26	Buy
Arctom	HY-12866R	Larotrectinib (Standard) 98%	10mg	$328	2026-05-26	Buy
Arctom	SLK-S5860	Larotrectinib 99.93%	5mg	$140	2026-05-26	Buy

Next Last

Properties

Density :1.55±0.1 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
pka :8.41±0.40(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501
H317	May cause an allergic skin reaction	Sensitisation, Skin	Category 1	Warning		P261, P272, P280, P302+P352,P333+P313, P321, P363, P501

Precautionary statements:

P280

Wear protective gloves/protective clothing/eye protection/face protection.

Description

LOXO-101 is an inhibitor of the tropomyosin-related kinases TrkA, TrkB, and TrkC (IC₅₀s = 2-20 nM). It is selective for TrkA, -B, and -C over a panel of 226 kinases at 1 μM. LOXO-101 inhibits the growth of CUTO-3.29, KM12, and MO-91 patient-derived cancer cell lines (IC₅₀s = <100, <10, and <10 nM, respectively). In vivo, LOXO-101 (60 and 200 mg/kg) reduces tumor growth in a KM12 mouse xenograft model.

More related product prices

BMN 673 Ibrutinib Abiraterone Vandetanib Olaparib Nintedanib Ethanesulfonate Salt AZD-9291 PF-06463922 Afatinib (BIBW 2992) Crizotinib Dacomitinib (PF299804) Poziotinib (HM781-36B) Neratinib Regorafenib

Suppliers and manufacturers

Hebei Yanxi Chemical Co., Ltd.

$50.00 /1kg
Larotrectinib CAS:1223403-58-4

shandong perfect biotechnology co.ltd

$0.00 /1g
Larotrectinib CAS:1223403-58-4

career henan chemical co

$1.00 /1kg
LOXO-101 CAS:1223403-58-4

Henan Tianfu Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

TianYuan Pharmaceutical CO.,LTD

Biochempartner

Jinan Carbotang Biotech Co.,Ltd.

Shenzhen Excellent Biotech Co., Ltd.

Jurong Coupling Biotechnology Co., Ltd.

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

LOXO-101

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers