Neratinib
|
- $28 - $5273
- Product name: Neratinib
- CAS: 698387-09-6
- MF: C30H29ClN6O3
- MW: 557.04
- EINECS:811-237-1
- MDL Number:MFCD09752958
- Synonyms:Neratinib(HKI-272);(2E)-N-[4-[[3-chloro-4-(2-pyridinylMethoxy)phenyl]aMino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(diMethylaMino)-2-butenaMide;neratinib;(E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide;N-(4-(3-Chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide;Unii-jjh94R3pwb;(2e)-n-(4-((3-chloro-4-((pyridin-2-yl)Methoxy)phenyl)aMino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(diMethylaMino)but-2-enaMide neratinib;HKI-272 Neratinib
39 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Chemtos
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 20mg
- 50mg
- 250mg
- 1000mg
- 5g
- 50 mg
- 100 mg
- 10mM(in 1mL DMSO)
- 1MG
- 1unit
- 5mg
- 10MG
- 25MG
- 100mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberCDX-N0326-M100
- Product descriptionNeratinib ≥98%
- Packaging100mg
- Price$141
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX2638
- Product descriptionNeratinib
- Packaging1g
- Price$2423
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA150970
- Product description(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
- Packaging1g
- Price$93
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0025184
- Product descriptionNERATINIB 95.00%
- Packaging1MG
- Price$203.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0025184
- Product descriptionNERATINIB 95.00%
- Packaging10MG
- Price$919.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0025184
- Product descriptionNERATINIB 95.00%
- Packaging25MG
- Price$1166.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8322
- Product descriptionNeratinib(HKI-272)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8322
- Product descriptionNeratinib(HKI-272)
- Packaging5mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8322
- Product descriptionNeratinib(HKI-272)
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8322
- Product descriptionNeratinib(HKI-272)
- Packaging25mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60191
- Product descriptionNeratinib(HKI-272)
- Packaging20mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2649
- Product descriptionNeratinib
- Packaging5mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2649
- Product descriptionNeratinib
- Packaging10mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2649
- Product descriptionNeratinib
- Packaging100mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2649
- Product descriptionNeratinib
- Packaging1g
- Price$449
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181066
- Product descriptionNeratinib (HKI-272) >99%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-N0326-M100 | Neratinib ≥98% | 100mg | $141 | 2021-12-16 | Buy |
| AK Scientific | X2638 | Neratinib | 1g | $2423 | 2021-12-16 | Buy |
| Ambeed | A150970 | (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% | 1g | $93 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0025184 | NERATINIB 95.00% | 1MG | $203.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0025184 | NERATINIB 95.00% | 10MG | $919.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0025184 | NERATINIB 95.00% | 25MG | $1166.9 | 2021-12-16 | Buy |
| ApexBio Technology | A8322 | Neratinib(HKI-272) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8322 | Neratinib(HKI-272) | 5mg | $35 | 2021-12-16 | Buy |
| ApexBio Technology | A8322 | Neratinib(HKI-272) | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A8322 | Neratinib(HKI-272) | 25mg | $95 | 2021-12-16 | Buy |
| Arctom | CFN60191 | Neratinib(HKI-272) | 20mg | $238 | 2021-12-16 | Buy |
| AvaChem | 2649 | Neratinib | 5mg | $39 | 2021-12-16 | Buy |
| AvaChem | 2649 | Neratinib | 10mg | $49 | 2021-12-16 | Buy |
| AvaChem | 2649 | Neratinib | 100mg | $139 | 2021-12-16 | Buy |
| AvaChem | 2649 | Neratinib | 1g | $449 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181066 | Neratinib (HKI-272) >99% | 100mg | $414.8 | 2021-12-16 | Buy |
Properties
Melting point :185-187°C
Boiling point :757.0±60.0 °C(Predicted)
Density :1.33
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated)
form :Off-white solid.
pka :12.37±0.43(Predicted)
color :Pale Yellow to Yellow
Boiling point :757.0±60.0 °C(Predicted)
Density :1.33
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated)
form :Off-white solid.
pka :12.37±0.43(Predicted)
color :Pale Yellow to Yellow
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
The receptor tyrosine kinase HER2 (ErbB2) is a key component of epidermal growth factor receptor complexes that are known to have central roles in cell proliferation and cancer. Neratinib is an orally active, irreversible inhibitor of the HER2 kinase (IC50 = 59 nM). It also potently inhibits several mutants of HER2 and shows 10-fold or greater selectivity over a wide variety of other kinases. As an irreversible inhibitor, neratinib may circumvent acquired resistance developed against reversible inhibitors, including gefitinib . Neratinib has been evaluated in clinical trials against cancers characterized by HER2 overexpression or HER2 activating mutations.More related product prices
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Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Anqing Chico Pharmaceutical Co., Ltd.
Zhejiang ZETian Fine Chemicals Co. LTD
