MK-2 Inhibitor III
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- $73 - $2000
- Product name: MK-2 Inhibitor III
- CAS: 1186648-22-5
- MF: C21H18N4O2
- MW: 358.4
- EINECS:
- MDL Number:
- Synonyms:MK-2 Inhibitor III;2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one:hydrate;MK-2 INHIBITOR III (COMPOUND 16);MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem;MK2-IN-3 hydrate;2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate;Inhibitor,MAP kinase activated protein kinase 2,inhibit,MK2 IN 3 hydrate,MAPKAP kinase 2,MK-2-IN-3 hydrate,MAPK activated protein kinase 2,MK2IN3 hydrate,MAPKAPK2 (MK2),Mitogen-activated protein kinase activated protein kinase 2
7 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Medical Isotopes, Inc.
Package
- 500μg
- 1mg
- 2.5mg
- 5mg
- 25mg
- ManufacturerAK Scientific
- Product number3003DC
- Product descriptionMK-2InhibitorIII
- Packaging1mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3003DC
- Product descriptionMK-2InhibitorIII
- Packaging5mg
- Price$348
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15943
- Product descriptionMK2 Inhibitor III ≥95%
- Packaging500μg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15943
- Product descriptionMK2 Inhibitor III ≥95%
- Packaging1mg
- Price$110
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15943
- Product descriptionMK2 Inhibitor III ≥95%
- Packaging5mg
- Price$225
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number47746
- Product descriptionMK2InhibitorIII
- Packaging2.5mg
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number47746
- Product descriptionMK2InhibitorIII
- Packaging25mg
- Price$2000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3003DC | MK-2InhibitorIII | 1mg | $220 | 2021-12-16 | Buy |
| AK Scientific | 3003DC | MK-2InhibitorIII | 5mg | $348 | 2021-12-16 | Buy |
| Cayman Chemical | 15943 | MK2 Inhibitor III ≥95% | 500μg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 15943 | MK2 Inhibitor III ≥95% | 1mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 15943 | MK2 Inhibitor III ≥95% | 5mg | $225 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 47746 | MK2InhibitorIII | 2.5mg | $625 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 47746 | MK2InhibitorIII | 25mg | $2000 | 2021-12-16 | Buy |
Properties
Melting point :>255°C (dec.)
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Pale yellow solid
color :Off-White to Pale Yellow
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Pale yellow solid
color :Off-White to Pale Yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It less potently blocks MK3 and MK5 (IC50s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC50 = 4.4 μM).Suppliers and manufacturers
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ShangHai Biochempartner Co.,Ltd
Shanghai Hongye Biotechnology Co. Ltd
Fan De(Beijing) Biotechnology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc