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ChemicalBook >> CAS DataBase List >> MK-2 Inhibitor III

MK-2 Inhibitor III

$44 - $2000
Product name: MK-2 Inhibitor III
CAS: 1186648-22-5
MF: C21H18N4O2
MW: 358.4
EINECS:
MDL Number:
Synonyms:MK-2 Inhibitor III;2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one:hydrate;MK-2 INHIBITOR III (COMPOUND 16);MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem;MK2-IN-3 hydrate;2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate;Inhibitor,MAP kinase activated protein kinase 2,inhibit,MK2 IN 3 hydrate,MAPKAP kinase 2,MK-2-IN-3 hydrate,MAPK activated protein kinase 2,MK2IN3 hydrate,MAPKAPK2 (MK2),Mitogen-activated protein kinase activated protein kinase 2;MK2-IN-3 hydrate, 10 mM in DMSO

Price32 Properties Safety Information Description

32 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
Arctom
Axon Medchem
Cayman Chemical
Chemenu
ChemScene
Medical Isotopes, Inc.

Package

10mM*1mLinDMSO(Solid+Solvent)
2.5mg
10mM*1mLinDMSO(Solution)
500μg
1mg
5mg
10mg
25mg
50mg
100mg
200mg

Manufactureraablocks
Product numberAA0097CY
Product description2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate
Packaging1mg
Price$44
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0097CY
Product description2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate
Packaging5mg
Price$67
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0097CY
Product description2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate
Packaging10mg
Price$96
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0097CY
Product description2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate
Packaging25mg
Price$172
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0097CY
Product description2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate
Packaging50mg
Price$242
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0097CY
Product description2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate
Packaging100mg
Price$332
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0097CY
Product description2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate
Packaging200mg
Price$447
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberY226220
Product descriptionMK2-IN-3 hydrate 97.00%
Packaging100MG
Price$465
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberY226220
Product descriptionMK2-IN-3 hydrate 97.00%
Packaging25MG
Price$225
Updated2026-05-27
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ManufacturerAK Scientific
Product number3003DC
Product descriptionMK-2InhibitorIII
Packaging1mg
Price$220
Updated2021-12-16
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ManufacturerAK Scientific
Product number3003DC
Product descriptionMK-2InhibitorIII
Packaging5mg
Price$348
Updated2021-12-16
Buy

ManufacturerArctom
Product numberHY-112457
Product descriptionMK2-IN-3 hydrate 98.03%
Packaging25mg
Price$608
Updated2026-05-26
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ManufacturerArctom
Product numberHY-112457
Product descriptionMK2-IN-3 hydrate 98.03%
Packaging50mg
Price$969
Updated2026-05-26
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ManufacturerArctom
Product numberHY-112457
Product descriptionMK2-IN-3 hydrate 98.03%
Packaging5mg
Price$190
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-112457
Product descriptionMK2-IN-3 hydrate 98.03%
Packaging10mg
Price$304
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-112457
Product descriptionMK2-IN-3 hydrate 98.03%
Packaging1mg
Price$95
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0097CY	2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate	1mg	$44	2026-05-28	Buy
aablocks	AA0097CY	2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate	5mg	$67	2026-05-28	Buy
aablocks	AA0097CY	2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate	10mg	$96	2026-05-28	Buy
aablocks	AA0097CY	2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate	25mg	$172	2026-05-28	Buy
aablocks	AA0097CY	2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate	50mg	$242	2026-05-28	Buy
aablocks	AA0097CY	2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate	100mg	$332	2026-05-28	Buy
aablocks	AA0097CY	2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate	200mg	$447	2026-05-28	Buy
ACHEMBLOCK	Y226220	MK2-IN-3 hydrate 97.00%	100MG	$465	2026-05-27	Buy
ACHEMBLOCK	Y226220	MK2-IN-3 hydrate 97.00%	25MG	$225	2026-05-27	Buy
AK Scientific	3003DC	MK-2InhibitorIII	1mg	$220	2021-12-16	Buy
AK Scientific	3003DC	MK-2InhibitorIII	5mg	$348	2021-12-16	Buy
Arctom	HY-112457	MK2-IN-3 hydrate 98.03%	25mg	$608	2026-05-26	Buy
Arctom	HY-112457	MK2-IN-3 hydrate 98.03%	50mg	$969	2026-05-26	Buy
Arctom	HY-112457	MK2-IN-3 hydrate 98.03%	5mg	$190	2026-05-26	Buy
Arctom	HY-112457	MK2-IN-3 hydrate 98.03%	10mg	$304	2026-05-26	Buy
Arctom	HY-112457	MK2-IN-3 hydrate 98.03%	1mg	$95	2026-05-26	Buy

Next Last

Properties

Melting point :>255°C (dec.)
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Pale yellow solid
color :Off-White to Pale Yellow
InChIKey :NIKCVKMHGQQSRN-UHFFFAOYSA-N
SMILES :[nH]1c2c(cc1c3cc(ncc3)c4cnc5c(c4)cccc5)C(=O)NCC2.O

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning		P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning		P264, P280, P305+P351+P338,P337+P313P

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.

Description

MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It less potently blocks MK3 and MK5 (IC50s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC50 = 4.4 μM).

More related product prices

PHA 767491 HYDROCHLORIDE 845538-12-7 MK-2 Inhibitor III

Suppliers and manufacturers

TargetMol Chemicals Inc.

$35.00
MK2-IN-3 hydrate CAS:1186648-22-5

BOC Sciences Shanghai YuanYe Biotechnology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Hongye Biotechnology Co. Ltd Fan De(Beijing) Biotechnology Co., Ltd. HANGZHOU CLAP TECHNOLOGY CO.,LTD ChemeGen(Shanghai) Biotechnology Co.,Ltd. Zhejiang Huida Biotech Co., LTD

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MK-2 Inhibitor III

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Description

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