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ChemicalBook >> CAS DataBase List >> Methoxy-X04

Methoxy-X04

Methoxy-X04 price.
  • $32 - $724
  • Product name: Methoxy-X04
  • CAS: 863918-78-9
  • MF: C23H20O3
  • MW: 344.4031
  • EINECS:
  • MDL Number:MFCD25563254
  • Synonyms:Methoxy-X04;4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol;MethoxyX04,Methoxy X04,Methoxy-X-04;Phenol, 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis- (9CI);4,4'-((1E,1'E)-(2-Methoxy-1,4-phenylene)bis(ethene-2,1-diyl))diphenol;4,4'-((1E,1'E)-(2-Methoxy-1,4-phenylene)bis(ethene-2,1-diyl))diphenol
9 prices
Selected condition:
Brand
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerApexBio Technology
  • Product numberB5769
  • Product descriptionMethoxy-X04
  • Packaging5mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5769
  • Product descriptionMethoxy-X04
  • Packaging10mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20476
  • Product descriptionMethoxy-X04 ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20476
  • Product descriptionMethoxy-X04 ≥95%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20476
  • Product descriptionMethoxy-X04 ≥95%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number4920
  • Product descriptionMethoxy-X04 ≥98%(HPLC)
  • Packaging10
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4920
  • Product descriptionMethoxy-X04 ≥98%(HPLC)
  • Packaging50
  • Price$724
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM350128
  • Product descriptionMethoxy-X04
  • Packaging5mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255797
  • Product descriptionMethoxy-X04
  • Packaging10mg
  • Price$418
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B5769 Methoxy-X04 5mg $123 2021-12-16 Buy
ApexBio Technology B5769 Methoxy-X04 10mg $192 2021-12-16 Buy
Cayman Chemical 20476 Methoxy-X04 ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 20476 Methoxy-X04 ≥95% 5mg $109 2024-03-01 Buy
Cayman Chemical 20476 Methoxy-X04 ≥95% 10mg $169 2024-03-01 Buy
Tocris 4920 Methoxy-X04 ≥98%(HPLC) 10 $173 2021-12-16 Buy
Tocris 4920 Methoxy-X04 ≥98%(HPLC) 50 $724 2021-12-16 Buy
TRC M350128 Methoxy-X04 5mg $330 2021-12-16 Buy
Usbiological 255797 Methoxy-X04 10mg $418 2021-12-16 Buy

Properties

Boiling point :554.2±29.0 °C(Predicted)
Density :1.244±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C,protect from light
solubility :Soluble in DMSO
form :crystalline solid
pka :9.98±0.26(Predicted)
color :Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Methoxy-X04 is a brain-permeable fluorescent probe for amyloid-β (Aβ) to detect and quantify plaques, tangles, and cerebrovascular amyloid. It displays high in vitro binding affinity (Ki = 26.8 nM) for fibrillar β-sheet deposits and is used to image Aβ plaques in the brains of living APP/PS1 mice, a transgenic model of familial Alzheimer''s disease. For in vivo imaging, APP/PS1 mice were injected with methoxy-X04 at a dose of 10 mg/kg, i.p., 24 hours prior to two-photon imaging. Methoxy-X04 displays an excitation peak at 750 nm with emission between 460 and 500 nm.