NQDI 1
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- $24 - $1400
- Product name: NQDI 1
- CAS: 175026-96-7
- MF: C19H13NO4
- MW: 319.31
- EINECS:
- MDL Number:MFCD03265970
- Synonyms:LESINURAD (RDEA-594) intermediate;2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester;NDQI 1;NQDI 1;3H-Naphtho[1,2,3-de]quinoline-1-carboxylic acid, 2,7-dihydro-2,7-dioxo-, ethyl ester;CS-1567;NQDI-1（97%）;NQDI-1;NQDI 1;NQDI1
60 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Synthonix
- Tocris
- TRC
- Usbiological
Package
- 10.00mg
- 2x10mg
- 25mg
- 10mM*1mLinDMSO(Solution)
- 25.00mg
- 200mg
- 50
- 50.00mg
- 10
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+%
- Packaging5mg
- Price$29
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+%
- Packaging10mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+%
- Packaging1mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96%
- Packaging50mg
- Price$72
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96%
- Packaging100mg
- Price$97
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+%
- Packaging250mg
- Price$225
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96%
- Packaging500mg
- Price$385
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABLW
- Product descriptionEthyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96%
- Packaging1g
- Price$745
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33690
- Product descriptionNQDI-1 98%
- Packaging1G
- Price$405
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33690
- Product descriptionNQDI-1 98%
- Packaging100MG
- Price$130
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number9994AF
- Product descriptionEthyl2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate
- Packaging5g
- Price$1315
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001447
- Product descriptionNQDI-1 95.00%
- Packaging10MG
- Price$275.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4474
- Product descriptionNQDI 1
- Packaging50mg
- Price$348
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4474
- Product descriptionNQDI 1
- Packaging100mg
- Price$525
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4474
- Product descriptionNQDI 1
- Packaging10mg
- Price$106
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4474
- Product descriptionNQDI 1
- Packaging5mg
- Price$63
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+% | 5mg | $29 | 2026-05-28 | Buy |
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+% | 10mg | $48 | 2026-05-28 | Buy |
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+% | 1mg | $24 | 2026-05-28 | Buy |
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96% | 50mg | $72 | 2026-05-28 | Buy |
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96% | 100mg | $97 | 2026-05-28 | Buy |
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 98+% | 250mg | $225 | 2026-05-28 | Buy |
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96% | 500mg | $385 | 2026-05-28 | Buy |
| aablocks | AA00ABLW | Ethyl 2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 96% | 1g | $745 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33690 | NQDI-1 98% | 1G | $405 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33690 | NQDI-1 98% | 100MG | $130 | 2026-05-27 | Buy |
| AK Scientific | 9994AF | Ethyl2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate | 5g | $1315 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001447 | NQDI-1 95.00% | 10MG | $275.1 | 2021-12-16 | Buy |
| ApexBio Technology | A4474 | NQDI 1 | 50mg | $348 | 2026-05-06 | Buy |
| ApexBio Technology | A4474 | NQDI 1 | 100mg | $525 | 2026-05-06 | Buy |
| ApexBio Technology | A4474 | NQDI 1 | 10mg | $106 | 2026-05-06 | Buy |
| ApexBio Technology | A4474 | NQDI 1 | 5mg | $63 | 2026-05-06 | Buy |
Properties
Melting point :310 °C (decomp)
Boiling point :581.4±50.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL (warmed to 60° C)
pka :10.76±0.40(Predicted)
form :powder
color :orange
Stability :Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChI :1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22)
InChIKey :UFJGFNHRMPMALC-UHFFFAOYSA-N
SMILES :CCOC(=O)C1=C2c3ccccc3C(=O)c4cccc(NC1=O)c24
Boiling point :581.4±50.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL (warmed to 60° C)
pka :10.76±0.40(Predicted)
form :powder
color :orange
Stability :Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChI :1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22)
InChIKey :UFJGFNHRMPMALC-UHFFFAOYSA-N
SMILES :CCOC(=O)C1=C2c3ccccc3C(=O)c4cccc(NC1=O)c24
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Apoptosis signal-regulating kinase 1 (ASK1) is the ubiquitously expressed mitogen-activated protein kinase kinase kinase 5 involved in a wide range of biological functions that are dependent on cell survival or death. NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases. It has been used to promote survival of induced pluripotent stem cell populations and to protect neurons from reactive oxygen species-induced apoptosis in a model of ischemia.More related product prices
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