NVP-TNKS656
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- $32 - $2930
- Product name: NVP-TNKS656
- CAS: 1419949-20-4
- MF: C27H34N4O5
- MW: 494.58
- EINECS:604-604-1
- MDL Number:MFCD28167762
- Synonyms:NVP-TNKS656;TNKS656;N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide;NVP-TNKS656 - TNKS 656;TNKS656; TNKS-656;TNKS 656;CS-1333;N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide;1-Piperidineacetamide, N-(cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-
69 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 500μg
- 10mM(in 1mL DMSO)
- 10mM*1mLinDMSO
- 250mg
- 1g
- 10mM(in1mLDMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99%
- Packaging1mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging2mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging5mg
- Price$85
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging10mg
- Price$125
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging25mg
- Price$240
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging50mg
- Price$395
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging100mg
- Price$569
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number7527EM
- Product descriptionNvp-tnks656
- Packaging5mg
- Price$556
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging1mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging10mg
- Price$353
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging25mg
- Price$599
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging5mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004719
- Product descriptionNVP-TNKS656 95.00%
- Packaging5MG
- Price$499.53
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6046
- Product descriptionNVP-TNKS656
- Packaging25mg
- Price$1080
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6046
- Product descriptionNVP-TNKS656
- Packaging50mg
- Price$1226
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6046
- Product descriptionNVP-TNKS656
- Packaging50mg
- Price$1800
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001HFF | NVP-TNKS656 99% | 1mg | $32 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 2mg | $62 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 5mg | $85 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 10mg | $125 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 25mg | $240 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 50mg | $395 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 100mg | $569 | 2026-05-28 | Buy |
| AK Scientific | 7527EM | Nvp-tnks656 | 5mg | $556 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 1mg | $59 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 10mg | $353 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 25mg | $599 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 5mg | $208 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004719 | NVP-TNKS656 95.00% | 5MG | $499.53 | 2021-12-16 | Buy |
| ApexBio Technology | B6046 | NVP-TNKS656 | 25mg | $1080 | 2021-12-16 | Buy |
| ApexBio Technology | B6046 | NVP-TNKS656 | 50mg | $1226 | 2026-05-06 | Buy |
| ApexBio Technology | B6046 | NVP-TNKS656 | 50mg | $1800 | 2021-12-16 | Buy |
Properties
Boiling point :700.7±70.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :6.66±0.10(Predicted)
color :White to light yellow
InChIKey :DYGBNAYFDZEYBA-UHFFFAOYSA-N
SMILES :N4(CCC(CC4)C(=O)c5ccc(cc5)OC)CC(=O)N(CC3CC3)Cc1[nH][c](c2c(n1)CCOC2)=O
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :6.66±0.10(Predicted)
color :White to light yellow
InChIKey :DYGBNAYFDZEYBA-UHFFFAOYSA-N
SMILES :N4(CCC(CC4)C(=O)c5ccc(cc5)OC)CC(=O)N(CC3CC3)Cc1[nH][c](c2c(n1)CCOC2)=O
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
NVP-TNKS656 is an orally bioavailable inhibitor of tankyrase 2 (TNKS2; IC50 = 6 nM). It is selective for TNKS2 over poly(ADP-ribose) polymerase (PARP) 1 and 2 (IC50s = >19 and 32 nM, respectively). NVP-TNKS656 inhibits Wnt ligand-induced signaling with an IC50 value of 3.5 nM in an HEK293 cell reporter assay. In vivo, NVP-TNKS656 (350 mg/kg) reduces Axin 2 mRNA expression, a Wnt/β-catenin target gene, in MMTV-Wnt1 tumor bearing mice.More related product prices
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