NVP-TNKS656
|
- $32 - $2632
- Product name: NVP-TNKS656
- CAS: 1419949-20-4
- MF: C27H34N4O5
- MW: 494.58
- EINECS:604-604-1
- MDL Number:MFCD28167762
- Synonyms:NVP-TNKS656;TNKS656;N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide;NVP-TNKS656 - TNKS 656;TNKS656; TNKS-656;TNKS 656;CS-1333;N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide;1-Piperidineacetamide, N-(cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-
54 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 500μg
- 10mM(in1mLDMSO)
- 250mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO
- 1g
- 10mM(in 1mL DMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99%
- Packaging1mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging2mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging5mg
- Price$85
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging10mg
- Price$125
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging25mg
- Price$240
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging50mg
- Price$395
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001HFF
- Product descriptionNVP-TNKS656 99
- Packaging100mg
- Price$569
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number7527EM
- Product descriptionNvp-tnks656
- Packaging5mg
- Price$556
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging10mg
- Price$353
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging5mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging1mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA474769
- Product descriptionNVP-TNKS656 98+%
- Packaging25mg
- Price$599
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004719
- Product descriptionNVP-TNKS656 95.00%
- Packaging5MG
- Price$499.53
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6046
- Product descriptionNVP-TNKS656
- Packaging10mM(in 1mL DMSO)
- Price$376
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6046
- Product descriptionNVP-TNKS656
- Packaging5mg
- Price$259
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6046
- Product descriptionNVP-TNKS656
- Packaging10mg
- Price$340
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001HFF | NVP-TNKS656 99% | 1mg | $32 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 2mg | $62 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 5mg | $85 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 10mg | $125 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 25mg | $240 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 50mg | $395 | 2026-05-28 | Buy |
| aablocks | AA001HFF | NVP-TNKS656 99 | 100mg | $569 | 2026-05-28 | Buy |
| AK Scientific | 7527EM | Nvp-tnks656 | 5mg | $556 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 10mg | $353 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 5mg | $208 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 1mg | $59 | 2021-12-16 | Buy |
| Ambeed | A474769 | NVP-TNKS656 98+% | 25mg | $599 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004719 | NVP-TNKS656 95.00% | 5MG | $499.53 | 2021-12-16 | Buy |
| ApexBio Technology | B6046 | NVP-TNKS656 | 10mM(in 1mL DMSO) | $376 | 2021-12-16 | Buy |
| ApexBio Technology | B6046 | NVP-TNKS656 | 5mg | $259 | 2026-05-06 | Buy |
| ApexBio Technology | B6046 | NVP-TNKS656 | 10mg | $340 | 2026-05-06 | Buy |
Properties
Boiling point :700.7±70.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :6.66±0.10(Predicted)
color :White to light yellow
InChIKey :DYGBNAYFDZEYBA-UHFFFAOYSA-N
SMILES :N4(CCC(CC4)C(=O)c5ccc(cc5)OC)CC(=O)N(CC3CC3)Cc1[nH][c](c2c(n1)CCOC2)=O
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :6.66±0.10(Predicted)
color :White to light yellow
InChIKey :DYGBNAYFDZEYBA-UHFFFAOYSA-N
SMILES :N4(CCC(CC4)C(=O)c5ccc(cc5)OC)CC(=O)N(CC3CC3)Cc1[nH][c](c2c(n1)CCOC2)=O
Safety Information
| Symbol(GHS): |
 
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
NVP-TNKS656 is an orally bioavailable inhibitor of tankyrase 2 (TNKS2; IC50 = 6 nM). It is selective for TNKS2 over poly(ADP-ribose) polymerase (PARP) 1 and 2 (IC50s = >19 and 32 nM, respectively). NVP-TNKS656 inhibits Wnt ligand-induced signaling with an IC50 value of 3.5 nM in an HEK293 cell reporter assay. In vivo, NVP-TNKS656 (350 mg/kg) reduces Axin 2 mRNA expression, a Wnt/β-catenin target gene, in MMTV-Wnt1 tumor bearing mice.More related product prices
BEZ235 (NVP-BEZ235, Dactolisib) NVP-TAE684 - TAE 684 NVP-BEP800 NVP-CGM097 TAE226 (NVP-TAE226) PEAQX NVP-BAW2881 872511-34-7Related product price
-
BEZ235 (NVP-BEZ235, Dactolisib)
$12-1871.1 -
NVP-TAE684 - TAE 684
$30-4070 -
NVP-BEP800
$36-3384.15
Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
Moltt Biocem Co., Ltd.
MedChemexpress LLC
LETOPHARM LIMITED
Shanghai Lollane Biological Technology Co.,Ltd.
SPIRO PHARMA
Shanghai EFE Biological Technology Co., Ltd.
Guangzhou QiYun Biotechnology Co., Ltd.