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ChemicalBook >> CAS DataBase List >> Infigratinib

Infigratinib

Infigratinib price.
  • $12 - $5344
  • Product name: Infigratinib
  • CAS: 872511-34-7
  • MF: C26H31Cl2N7O3
  • MW: 560.48
  • EINECS:
  • MDL Number:MFCD22123241
  • Synonyms:3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea;BGJ 398;BGJ398 (NVP-BGJ398);NVP-BGJ398 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea;Urea, N'-(2,6-dichloro-3,5-dimethoxyphenyl)-N-[6-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-N-methyl-, methanesulfonate;Urea, N'-(2,6-dichloro-3,5-dimethoxyphenyl)-N-[6-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-N-methyl-;NVP-BGJ398, >=98%;NVP-BGJ398 (Infigratinib)
Price102 Properties Safety Information Description
102 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 200mg
  • 20mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO
  • 250mg
  • 2g
  • 5g
  • EvaluationSample
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 500mg
  • 1G
  • Manufactureraablocks
  • Product numberAA00GU27
  • Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
  • Packaging25mg
  • Price$54
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU27
  • Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
  • Packaging50mg
  • Price$65
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU27
  • Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
  • Packaging100mg
  • Price$102
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU27
  • Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea
  • Packaging500mg
  • Price$408
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU27
  • Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
  • Packaging10mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU27
  • Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea ≥98%
  • Packaging5mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU27
  • Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
  • Packaging1mg
  • Price$12
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product number10291
  • Product descriptionBGJ398 98%
  • Packaging1G
  • Price$1550
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product number10291
  • Product descriptionBGJ398 98%
  • Packaging5MG
  • Price$65
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10291
  • Product descriptionBGJ398 98%
  • Packaging100MG
  • Price$450
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10291
  • Product descriptionBGJ398 98%
  • Packaging25MG
  • Price$150
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1152-M005
  • Product descriptionNVP-BGJ398 ≥95%
  • Packaging5mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1152-M005
  • Product descriptionNVP-BGJ398 ≥95%
  • Packaging5mg
  • Price$113
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1152-M010
  • Product descriptionNVP-BGJ398 ≥95%
  • Packaging10mg
  • Price$178
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1152-M050
  • Product descriptionNVP-BGJ398 ≥95%
  • Packaging50mg
  • Price$416
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1152-M100
  • Product descriptionNVP-BGJ398 ≥95%
  • Packaging100mg
  • Price$578
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GU27 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+% 25mg $54 2026-05-28 Buy
aablocks AA00GU27 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+% 50mg $65 2026-05-28 Buy
aablocks AA00GU27 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+% 100mg $102 2026-05-28 Buy
aablocks AA00GU27 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 500mg $408 2026-05-28 Buy
aablocks AA00GU27 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+% 10mg $36 2026-05-28 Buy
aablocks AA00GU27 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea ≥98% 5mg $21 2026-05-28 Buy
aablocks AA00GU27 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+% 1mg $12 2026-05-28 Buy
ACHEMBLOCK 10291 BGJ398 98% 1G $1550 2026-05-27 Buy
ACHEMBLOCK 10291 BGJ398 98% 5MG $65 2026-05-27 Buy
ACHEMBLOCK 10291 BGJ398 98% 100MG $450 2026-05-27 Buy
ACHEMBLOCK 10291 BGJ398 98% 25MG $150 2026-05-27 Buy
Adipogen Life Sciences SYN-1152-M005 NVP-BGJ398 ≥95% 5mg $113 2021-12-16 Buy
Adipogen Life Sciences SYN-1152-M005 NVP-BGJ398 ≥95% 5mg $113 2026-05-06 Buy
Adipogen Life Sciences SYN-1152-M010 NVP-BGJ398 ≥95% 10mg $178 2026-05-06 Buy
Adipogen Life Sciences SYN-1152-M050 NVP-BGJ398 ≥95% 50mg $416 2026-05-06 Buy
Adipogen Life Sciences SYN-1152-M100 NVP-BGJ398 ≥95% 100mg $578 2026-05-06 Buy
Next Last

Properties

Melting point :>211°C (dec.)
Boiling point :747.9±60.0 °C(Predicted)
Density :1.354
storage temp. :-20°C
solubility :Soluble in DMSO (up to 5 mg/ml)
form :White solid.
pka :11.02±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :QADPYRIHXKWUSV-UHFFFAOYSA-N
SMILES :N(C1C=C(NC2=CC=C(N3CCN(CC)CC3)C=C2)N=CN=1)(C)C(NC1=C(Cl)C(OC)=CC(OC)=C1Cl)=O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

BGJ398 is an orally available inhibitor of human FGFRs (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It inhibits FGFR4 and VEGFR2 with IC50 values of 60 and 180 nM, respectively, and displays comparatively little activity towards Abl, Fyn, Kit, Lck, Lyn, and Yes (IC50s = 0.3-2.5 μM). BGJ398 has been shown to suppress proliferation of cancer cells with wild-type FGFR3 overexpression (IC50s = 5, 30, 32, and 15 nM, for RT112, RT4, SW780, and JMSU1 cells, respectively). In an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3, BGJ398 inhibited tumor growth after oral administration of 10-30 mg/kg.

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Suppliers and manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
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Shaanxi Dideu Medichem Co. Ltd
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Shaanxi Dideu Medichem Co. Ltd
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shandong perfect biotechnology co.ltd
Infigratinib (BGJ398)
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career henan chemical co
3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea
$2.00
3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea CAS:872511-34-7
PharmOrgSyn Laboratories Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED