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ChemicalBook >> CAS DataBase List >> Nimesulide

Nimesulide

Nimesulide price.
  • $5 - $5058.9
  • Product name: Nimesulide
  • CAS: 51803-78-2
  • MF: C13H12N2O5S
  • MW: 308.31
  • EINECS:257-431-4
  • MDL Number:MFCD00079470
  • Synonyms:nimed ;4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE;CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD);4-Nitro-2-phenoxymethanesulfonamide;Nide;Nidol
48 prices
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Brand

  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological

Package

  • y0001237
  • 500mg
  • 1000mg
  • 5000mg
  • 25000mg
  • 100g
  • n0845000
  • 100
  • 10mM(in 1mL DMSO)
  • 5MG
  • 25mg
  • 100mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 250g
  • ManufacturerAHH
  • Product numberMT-57002
  • Product descriptionNimesulide 99%
  • Packaging250g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11497
  • Product descriptionNimesulide
  • Packaging25mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50241
  • Product descriptionNimesulide
  • Packaging5g
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63699
  • Product descriptionNimesulide
  • Packaging5g
  • Price$53.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63699
  • Product descriptionNimesulide
  • Packaging25g
  • Price$219.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging100mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging5g
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging10g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA370794
  • Product descriptionN-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+%
  • Packaging25g
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000297
  • Product descriptionNIMESULIDE 95.00%
  • Packaging1G
  • Price$120.75
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0294404
  • Product descriptionN-(4-NITRO-2-PHENOXYPHENYL)METHANE SULPHONAMIDE 95.00%
  • Packaging5MG
  • Price$500.31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000297
  • Product descriptionNIMESULIDE 95.00%
  • Packaging25G
  • Price$1166.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000297
  • Product descriptionNIMESULIDE 95.00%
  • Packaging250G
  • Price$5058.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1452
  • Product descriptionNimesulide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-57002 Nimesulide 99% 250g $400 2021-12-16 Buy
AK Scientific J11497 Nimesulide 25mg $29 2021-12-16 Buy
AK Scientific J50241 Nimesulide 5g $35 2021-12-16 Buy
Alfa Aesar J63699 Nimesulide 5g $53.65 2024-03-01 Buy
Alfa Aesar J63699 Nimesulide 25g $219.65 2024-03-01 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 25mg $5 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 100mg $8 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 1g $11 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 5g $22 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 10g $39 2021-12-16 Buy
Ambeed A370794 N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide 98+% 25g $59 2021-12-16 Buy
American Custom Chemicals Corporation INB0000297 NIMESULIDE 95.00% 1G $120.75 2021-12-16 Buy
American Custom Chemicals Corporation CHM0294404 N-(4-NITRO-2-PHENOXYPHENYL)METHANE SULPHONAMIDE 95.00% 5MG $500.31 2021-12-16 Buy
American Custom Chemicals Corporation INB0000297 NIMESULIDE 95.00% 25G $1166.55 2021-12-16 Buy
American Custom Chemicals Corporation INB0000297 NIMESULIDE 95.00% 250G $5058.9 2021-12-16 Buy
ApexBio Technology B1452 Nimesulide 10mM(in 1mL DMSO) $50 2021-12-16 Buy

Properties

Melting point :140-146°C
Boiling point :442.0±55.0 °C(Predicted)
Density :1.451±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in acetone, slightly soluble in anhydrous ethanol.
pka :pKa 6.56± 0.03(H2O,t =25,I=0.02)(Approximate)
color :Light orange to Yellow to Green
Water Solubility :Soluble in water (<50 &#181;g/ml), 1:10 DMSO:PBS (pH 7.2) (<200 &#181;g/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.
λmax :391nm(H2O)(lit.)
Merck :14,6548
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :HYWYRSMBCFDLJT-UHFFFAOYSA-N
CAS DataBase Reference :51803-78-2(CAS DataBase Reference)
EPA Substance Registry System :Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)- (51803-78-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. It is indicated for the treatment of acute pain, symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults. However, due to the risk of causing hepatotoxicity, it should not be taken long-term. It has also been withdrawn from the markets in many countries. It mechanism of action is through targeting on various key mediators in the inflammatory process such as COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine.

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