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ChemicalBook >> CAS DataBase List >> O-Desmethylvenlafaxine

O-Desmethylvenlafaxine

O-Desmethylvenlafaxine price.
  • $5 - $1440
  • Product name: O-Desmethylvenlafaxine
  • CAS: 93413-62-8
  • MF: C16H25NO2
  • MW: 263.38
  • EINECS:700-516-2
  • MDL Number:MFCD00871934
  • Synonyms:O-DESMETHYL VENLAFAXINE-D10;DL-O-Desmethylvenlafaxin;4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol;O-Desmethylvenlafaxine;Desvenlafaxine(O-Desnethylvenfaxine);1-[1-(4-Hydroxyphenyl)-2-dimethylaminoethyl]cyclohexanol;4-[1-(1-Hydroxycyclohexyl)-2-(dimethylamino)ethyl]phenol;Desmethylvenlafaxine
38 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 1mg
  • 10mM(in 1mL DMSO)
  • 1unit
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1mL
  • 1g
  • 5ml
  • 5g
  • 10g
  • 25g
  • 100g
  • ManufacturerAK Scientific
  • Product numberJ10126
  • Product descriptionO-Desmethylvenlafaxine
  • Packaging100mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging5mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging10mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging1g
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging5g
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging10g
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging25g
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA105155
  • Product descriptionDesvenlafaxine 98+%
  • Packaging100g
  • Price$821
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRME0005567
  • Product descriptionO-DESMETHYL VENLAFAXINE-D10 95.00%
  • Packaging5MG
  • Price$502.82
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2236
  • Product descriptionDesvenlafaxine
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2236
  • Product descriptionDesvenlafaxine
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2236
  • Product descriptionDesvenlafaxine
  • Packaging25mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2236
  • Product descriptionDesvenlafaxine
  • Packaging100mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21342
  • Product descriptionD,L-O-Desmethyl venlafaxine
  • Packaging25mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21342
  • Product descriptionD,L-O-Desmethyl venlafaxine
  • Packaging50mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21342
  • Product descriptionD,L-O-Desmethyl venlafaxine
  • Packaging100mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10126 O-Desmethylvenlafaxine 100mg $195 2021-12-16 Buy
Ambeed A105155 Desvenlafaxine 98+% 5mg $5 2021-12-16 Buy
Ambeed A105155 Desvenlafaxine 98+% 10mg $6 2021-12-16 Buy
Ambeed A105155 Desvenlafaxine 98+% 1g $16 2021-12-16 Buy
Ambeed A105155 Desvenlafaxine 98+% 5g $56 2021-12-16 Buy
Ambeed A105155 Desvenlafaxine 98+% 10g $105 2021-12-16 Buy
Ambeed A105155 Desvenlafaxine 98+% 25g $221 2021-12-16 Buy
Ambeed A105155 Desvenlafaxine 98+% 100g $821 2021-12-16 Buy
American Custom Chemicals Corporation RME0005567 O-DESMETHYL VENLAFAXINE-D10 95.00% 5MG $502.82 2021-12-16 Buy
ApexBio Technology B2236 Desvenlafaxine 1unit $28 2021-12-16 Buy
ApexBio Technology B2236 Desvenlafaxine 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B2236 Desvenlafaxine 25mg $77 2021-12-16 Buy
ApexBio Technology B2236 Desvenlafaxine 100mg $259 2021-12-16 Buy
Biosynth Carbosynth FD21342 D,L-O-Desmethyl venlafaxine 25mg $40 2021-12-16 Buy
Biosynth Carbosynth FD21342 D,L-O-Desmethyl venlafaxine 50mg $75 2021-12-16 Buy
Biosynth Carbosynth FD21342 D,L-O-Desmethyl venlafaxine 100mg $140 2021-12-16 Buy

Properties

Melting point :208-213°C
Boiling point :403.8±25.0 °C(Predicted)
Density :1.115±0.06 g/cm3(Predicted)
Flash point :9℃
storage temp. :2-8°C
solubility :insoluble in EtOH; ≥13.2 mg/mL in DMSO; ≥2.45 mg/mL in EtOH
pka :10.04±0.26(Predicted)
InChIKey :KYYIDSXMWOZKMP-UHFFFAOYSA-N
LogP :0.33 at 25℃ and pH6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Desvenlafaxine is a new member of the SNRI class of antidepressants. It is marketed as an extended release tablet for once-daily oral treatment of MDD in adult patients. Desvenlafaxine (O-desmethylvenlafaxine) is the major active metabolite of the previously marketed antidepressant venlafaxine (Effexor). Similar to venlafaxine, desvenlafaxine is a more potent inhibitor of serotonin and norepinephrine reuptake (IC50=47 and 531 nM, respectively) than that of dopamine (62% inhibition at 100 mM) in in vitro studies. It does not have significant in vitro affinity for other neurotransmitter reporters such as a1-adrenergic, H1-histaminergic, or muscarine-cholinergic receptors. Desvenlafaxine is marketed as a racemic mixture. Specific pharmacological properties of the enantiomers of desvenlafaxine have not been reported.

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