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ChemicalBook >> CAS DataBase List >> OSu-03012

OSu-03012

OSu-03012 price.
  • $15 - $5833
  • Product name: OSu-03012
  • CAS: 742112-33-0
  • MF: C26H19F3N4O
  • MW: 460.45
  • EINECS:-0
  • MDL Number:MFCD12912272
  • Synonyms:OSU-03012, >=98%;OSU-03012 (AR-12);2-amino-N-(4-(5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)acetamide;2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide OSU-03012;N/AAR-12;2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide;OSU-03012 (AR-12);N/AAR-12; OSU03012; OSU 03012;CS-1848
Price58 Properties Safety Information Description
58 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Matrix Scientific
  • Tocris
  • TRC
Package
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  • 10
  • 10mM(in1mLDMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 200mg
  • 100mg
  • 10mM*1mLinDMSO(Solution)
  • Manufactureraablocks
  • Product numberAA00FENM
  • Product descriptionOSU-03012 99%
  • Packaging1mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FENM
  • Product descriptionOSU-03012 99%
  • Packaging5mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FENM
  • Product descriptionOSU-03012 99%
  • Packaging10mg
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FENM
  • Product descriptionOSU-03012 99
  • Packaging50mg
  • Price$242
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FENM
  • Product descriptionOSU-03012 99
  • Packaging100mg
  • Price$314
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FENM
  • Product descriptionOSU-03012 99
  • Packaging200mg
  • Price$402
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15129
  • Product descriptionOSU03012 98%
  • Packaging50MG
  • Price$430
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15129
  • Product descriptionOSU03012 98%
  • Packaging25MG
  • Price$215
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15129
  • Product descriptionOSU03012 98%
  • Packaging5MG
  • Price$75
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0267
  • Product descriptionOSU-03012
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA152748
  • Product descriptionOSU-03012 99%
  • Packaging1mg
  • Price$15
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA152748
  • Product descriptionOSU-03012 99%
  • Packaging10mg
  • Price$65
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA152748
  • Product descriptionOSU-03012 99%
  • Packaging5mg
  • Price$40
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA152748
  • Product descriptionOSU-03012 99%
  • Packaging25mg
  • Price$128
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA152748
  • Product descriptionOSU-03012 99%
  • Packaging100mg
  • Price$417
  • Updated2026-06-05
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000876
  • Product descriptionOSU-03012 95.00%
  • Packaging25MG
  • Price$808.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00FENM OSU-03012 99% 1mg $16 2026-05-28 Buy
aablocks AA00FENM OSU-03012 99% 5mg $32 2026-05-28 Buy
aablocks AA00FENM OSU-03012 99% 10mg $52 2026-05-28 Buy
aablocks AA00FENM OSU-03012 99 50mg $242 2026-05-28 Buy
aablocks AA00FENM OSU-03012 99 100mg $314 2026-05-28 Buy
aablocks AA00FENM OSU-03012 99 200mg $402 2026-05-28 Buy
ACHEMBLOCK M15129 OSU03012 98% 50MG $430 2026-05-27 Buy
ACHEMBLOCK M15129 OSU03012 98% 25MG $215 2026-05-27 Buy
ACHEMBLOCK M15129 OSU03012 98% 5MG $75 2026-05-27 Buy
AK Scientific Y0267 OSU-03012 5mg $70 2021-12-16 Buy
Ambeed A152748 OSU-03012 99% 1mg $15 2026-06-05 Buy
Ambeed A152748 OSU-03012 99% 10mg $65 2026-06-05 Buy
Ambeed A152748 OSU-03012 99% 5mg $40 2026-06-05 Buy
Ambeed A152748 OSU-03012 99% 25mg $128 2026-06-05 Buy
Ambeed A152748 OSU-03012 99% 100mg $417 2026-06-05 Buy
American Custom Chemicals Corporation INB0000876 OSU-03012 95.00% 25MG $808.5 2021-12-16 Buy
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Properties

storage temp. :Store at -20°C
solubility :≥23 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
color :White to off-white
CAS DataBase Reference :742112-33-0

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Cyclooxygenase-2 (COX-2) appears to play a significant role in the development and progression of cancer and COX-2 inhibitors such as celecoxib exhibit anti-cancer activity. OSU03012 is an analog of celecoxib that exhibits anti-cancer activity in a COX-2-independent manner via inhibition of the phosphatidyl inositol-3-kinase/Akt pathway. It has an IC50 value of 5 μM for inhibition of 3-phosphoinositide-dependent kinase-1, and therefore Akt activation, with no measurable COX-2 inhibition up to 50 μM. OSU03012 is a potent inhibitor of tumor cell growth with an average inhibitory concentration of 1.1 μM across a panel of 60 cancer cell lines. It does not inhibit signal transduction through the mitogen-activated protein kinase (MAPK) pathway. OSU03012 induces apoptosis of chronic lymphocytic leukemia cells independent of bcl-2 overexpression using both caspase-dependent and independent pathways.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited JinYan Chemicals(ShangHai) Co.,Ltd. VDM Biochemicals Jinan Trio PharmaTech Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai civi chemical technology co.,Ltd NCE Biomedical Co.,Ltd. Shanghai T&W Pharmaceutical Co., Ltd. Nanjing Norris-Pharm Technology Co., Ltd