Sildenafil citrate
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- $5 - $1880
- Product name: Sildenafil citrate
- CAS: 171599-83-0
- MF: C28H38N6O11S
- MW: 666.7
- EINECS:200-659-6
- MDL Number:MFCD02102122
- Synonyms:1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate salt;1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, 2-hydroxy-1,2,3-propanetricarboxylate;Sildenafil Citrate (100 mg);Sildenafil citrate, >=99%;Sildenafil citrate, Professional supply;5-[2-Ethoxy-5-[(4-methyl-piperazin-1-yl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one citrate;5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]py;SILDENAFIL CITRATE PH.EUR
43 prices
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Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 5mg
- 10MG
- 20mg
- 2x10mg
- 50mg
- 10mM(in 1mL DMSO)
- 25mg
- y0001578
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 5g
- 10g
- 25g
- 100g
- 500g
- 1kg
- ManufacturerAdipogen Life Sciences
- Product numberCDX-S0078-M250
- Product descriptionSildenafil Citrate ≥98%(HPLC)
- Packaging250mg
- Price$471
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberE241
- Product descriptionSildenafil Citrate
- Packaging5mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA523537
- Product description5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98%
- Packaging250mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA523537
- Product description5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98%
- Packaging5g
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA523537
- Product description5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98%
- Packaging25g
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA523537
- Product description5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98%
- Packaging100g
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA523537
- Product description5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98%
- Packaging500g
- Price$292
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA523537
- Product description5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98%
- Packaging1kg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000831
- Product descriptionSILDENAFIL CITRATE 95.00%
- Packaging10MG
- Price$154.35
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4321
- Product descriptionSildenafil Citrate
- Packaging25mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4321
- Product descriptionSildenafil Citrate
- Packaging50mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4321
- Product descriptionSildenafil Citrate
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4321
- Product descriptionSildenafil Citrate
- Packaging500mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60304
- Product descriptionSildenafil Citrate
- Packaging20mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3132
- Product descriptionSildenafil Citrate
- Packaging25mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3132
- Product descriptionSildenafil Citrate
- Packaging1g
- Price$129
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-S0078-M250 | Sildenafil Citrate ≥98%(HPLC) | 250mg | $471 | 2021-12-16 | Buy |
| AK Scientific | E241 | Sildenafil Citrate | 5mg | $29 | 2021-12-16 | Buy |
| Ambeed | A523537 | 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98% | 250mg | $5 | 2021-12-16 | Buy |
| Ambeed | A523537 | 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98% | 5g | $9 | 2021-12-16 | Buy |
| Ambeed | A523537 | 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98% | 25g | $30 | 2021-12-16 | Buy |
| Ambeed | A523537 | 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98% | 100g | $99 | 2021-12-16 | Buy |
| Ambeed | A523537 | 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98% | 500g | $292 | 2021-12-16 | Buy |
| Ambeed | A523537 | 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one2-hydroxypropane-1,2,3-tricarboxylate 98% | 1kg | $455 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000831 | SILDENAFIL CITRATE 95.00% | 10MG | $154.35 | 2021-12-16 | Buy |
| ApexBio Technology | A4321 | Sildenafil Citrate | 25mg | $40 | 2021-12-16 | Buy |
| ApexBio Technology | A4321 | Sildenafil Citrate | 50mg | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A4321 | Sildenafil Citrate | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A4321 | Sildenafil Citrate | 500mg | $240 | 2021-12-16 | Buy |
| Arctom | CFN60304 | Sildenafil Citrate | 20mg | $50 | 2021-12-16 | Buy |
| AvaChem | 3132 | Sildenafil Citrate | 25mg | $35 | 2021-12-16 | Buy |
| AvaChem | 3132 | Sildenafil Citrate | 1g | $129 | 2021-12-16 | Buy |
Properties
Melting point :187-189°C
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :white powder
color :White
Water Solubility :3.488g/L(temperature not stated)
Merck :14,8489
BCS Class :1
Stability :Store in Freezer
InChIKey :DEIYFTQMQPDXOT-UHFFFAOYSA-N
SMILES :C1(=CC(=CC=C1OCC)S(=O)(=O)N1CCN(C)CC1)C1=NC(C2N(N=C(CCC)C=2N1)C)=O.C(O)(C(=O)O)(CC(=O)O)CC(=O)O
CAS DataBase Reference :171599-83-0(CAS DataBase Reference)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :white powder
color :White
Water Solubility :3.488g/L(temperature not stated)
Merck :14,8489
BCS Class :1
Stability :Store in Freezer
InChIKey :DEIYFTQMQPDXOT-UHFFFAOYSA-N
SMILES :C1(=CC(=CC=C1OCC)S(=O)(=O)N1CCN(C)CC1)C1=NC(C2N(N=C(CCC)C=2N1)C)=O.C(O)(C(=O)O)(CC(=O)O)CC(=O)O
CAS DataBase Reference :171599-83-0(CAS DataBase Reference)
Safety Information
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Description
Cyclic guanosine monophosphate (cGMP) is a second messenger produced by guanylate cyclase, which in turn is activated by endogenous substances such as nitric oxide and atrial natriuretic peptide. cGMP can be degraded via members of the phosphodiesterase (PDE) protein family, including PDE1, PDE3, and PDE5. Sildenafil Citrate, formulated for human use and marketed under the trade name Viagra?, is a potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. It inhibits PDE5 activity in isolated rabbit platelets with an IC50 value of 3.6 nM (3 nM in human corpus cavernosum) compared to inhibition of PDE1 and PDE3 activities (IC50s = 0.26 and 65 μM, respectively). Inhibition of PDE5 enhances the relaxation of smooth muscle in a range of vascular tissues by prolonging the nitric oxide/cGMP-mediated activation of cGMP-dependent protein kinase. While most notable for its use in the treatment of erectile dysfunction, sildenafil’s vasorelaxant properties have also been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness. The citrate salt has superior water solubility and pharmacokinetics compared to the base salt of sildenafil.Related product price
- Sodium citrate
$6-1030 - Ethoxyamine hydrochloride
$5-1146.05 - Kresoxim-methyl
$44-990
Suppliers and manufacturers
Hebei Lingding Biotechnology Co., Ltd.
CONTIDE BIOTECH CO.,LTD
Firsky International Trade (Wuhan) Co., Ltd
