PD04217903
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- $17 - $4183.99
- Product name: PD04217903
- CAS: 956905-27-4
- MF: C19H16N8O
- MW: 372.38
- EINECS:
- MDL Number:MFCD12407410
- Synonyms:PD04217903;2-[4-[1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazol-1-yl]ethanol;2-(4-(3-(quinolin-6-ylmethyl)-3H-[1,2,3]triazolo[4,5-b]pyrazin-5-yl)-1H-pyrazol-1-yl)ethanol;2-[4-[1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazol-1-yl]ethanol PF 04217903;PF 04217903 2-[4-[1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazol-1-yl]ethanol;2-{4-[1-(6-Quinolinylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-y l]-1H-pyrazol-1-yl}ethanol;PF-04217903;PF 04217903;2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
66 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 25mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 25.00mg
- 100.00mg
- 1g
- 10mM*1mLinDMSO
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 250MG
- 50mg
- 100MG
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA01CP35
- Product descriptionPF-04217903 99%
- Packaging1mg
- Price$17
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01CP35
- Product descriptionPF-04217903 99%
- Packaging5mg
- Price$34
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01CP35
- Product descriptionPF-04217903 99%
- Packaging10mg
- Price$51
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01CP35
- Product descriptionPF-04217903 99
- Packaging50mg
- Price$197
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberT95385
- Product descriptionPD04217903 98%
- Packaging100MG
- Price$375
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT95385
- Product descriptionPD04217903 98%
- Packaging100MG
- Price$375
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT95385
- Product descriptionPD04217903 98%
- Packaging250MG
- Price$750
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT95385
- Product descriptionPD04217903 98%
- Packaging250MG
- Price$750
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1060-M050
- Product descriptionPF-04217903 ≥95%
- Packaging50mg
- Price$486
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1060-M050
- Product descriptionPF-04217903 ≥95%
- Packaging50mg
- Price$486
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1060-M010
- Product descriptionPF-04217903 ≥95%
- Packaging10mg
- Price$173
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1060-M005
- Product descriptionPF-04217903 ≥95%
- Packaging5mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1060-M005
- Product descriptionPF-04217903 ≥95%
- Packaging5mg
- Price$119
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1060-M001
- Product descriptionPF-04217903 ≥95%
- Packaging1mg
- Price$65
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberSYN1060
- Product descriptionPF04217903
- Packaging50mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000776
- Product descriptionPD-04217903 95.00%
- Packaging5MG
- Price$2934.86
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01CP35 | PF-04217903 99% | 1mg | $17 | 2026-05-29 | Buy |
| aablocks | AA01CP35 | PF-04217903 99% | 5mg | $34 | 2026-05-29 | Buy |
| aablocks | AA01CP35 | PF-04217903 99% | 10mg | $51 | 2026-05-29 | Buy |
| aablocks | AA01CP35 | PF-04217903 99 | 50mg | $197 | 2026-05-29 | Buy |
| ACHEMBLOCK | T95385 | PD04217903 98% | 100MG | $375 | 2026-05-25 | Buy |
| ACHEMBLOCK | T95385 | PD04217903 98% | 100MG | $375 | 2026-05-27 | Buy |
| ACHEMBLOCK | T95385 | PD04217903 98% | 250MG | $750 | 2026-05-25 | Buy |
| ACHEMBLOCK | T95385 | PD04217903 98% | 250MG | $750 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1060-M050 | PF-04217903 ≥95% | 50mg | $486 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1060-M050 | PF-04217903 ≥95% | 50mg | $486 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1060-M010 | PF-04217903 ≥95% | 10mg | $173 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1060-M005 | PF-04217903 ≥95% | 5mg | $119 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1060-M005 | PF-04217903 ≥95% | 5mg | $119 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1060-M001 | PF-04217903 ≥95% | 1mg | $65 | 2026-05-06 | Buy |
| AK Scientific | SYN1060 | PF04217903 | 50mg | $470 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000776 | PD-04217903 95.00% | 5MG | $2934.86 | 2021-12-16 | Buy |
Properties
Boiling point :718.1±60.0 °C(Predicted)
Density :1.53
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥18.6 mg/mL in DMSO
pka :14.31±0.10(Predicted)
form :solid
color :White to off-white
Density :1.53
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥18.6 mg/mL in DMSO
pka :14.31±0.10(Predicted)
form :solid
color :White to off-white
Safety Information
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Description
MET is a proto-oncogene that encodes the hepatocyte growth factor receptor c-Met. It has normal roles in morphogenesis, migration, apoptosis, and angiogenesis. Dysregulation of c-Met occurs in many types of cancer. PF-04217903 is a class I c-Met kinase inhibitor (Ki = 4.8 nM) that demonstrates more than 1,000-fold selectivity for c-Met compared with more than 150 kinases. It can inhibit tumor cell proliferation, survival, and migration/invasion in MET-amplified cell lines in vitro (IC50s = 12-31 nM), and shows antitumor activity in in vivo tumor models harboring either MET gene amplification or a hepatocyte growth factor/c-Met autocrine loop. PF-04217903 underwent phase I clinical trials in 2010.More related product prices
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