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ChemicalBook >> CAS DataBase List >> PD168393

PD168393

PD168393 price.
  • $18 - $1320
  • Product name: PD168393
  • CAS: 194423-15-9
  • MF: C17H13BrN4O
  • MW: 369.22
  • EINECS:
  • MDL Number:MFCD02179207
  • Synonyms:4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;PD 168393;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-;N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide;PD168393;PD-168393;PD 168393;CS-2316;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
33 prices
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Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 2mg
  • 10mM(in 1mL DMSO)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number2635AH
  • Product descriptionN-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
  • Packaging10mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2635AH
  • Product descriptionN-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
  • Packaging250mg
  • Price$459
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging1mg
  • Price$18
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging2mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging5mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging10mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging25mg
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging50mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging100mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137778
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
  • Packaging250mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2024
  • Product descriptionPD168393
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2024
  • Product descriptionPD168393
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2024
  • Product descriptionPD168393
  • Packaging25mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21059
  • Product descriptionPD 168393 ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21059
  • Product descriptionPD 168393 ≥95%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21059
  • Product descriptionPD 168393 ≥95%
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2635AH N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide 10mg $146 2021-12-16 Buy
AK Scientific 2635AH N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide 250mg $459 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 1mg $18 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 2mg $26 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 5mg $39 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 10mg $58 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 25mg $87 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 50mg $130 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 100mg $195 2021-12-16 Buy
Ambeed A137778 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 250mg $312 2021-12-16 Buy
ApexBio Technology A2024 PD168393 5mg $65 2021-12-16 Buy
ApexBio Technology A2024 PD168393 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology A2024 PD168393 25mg $255 2021-12-16 Buy
Cayman Chemical 21059 PD 168393 ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 21059 PD 168393 ≥95% 5mg $100 2024-03-01 Buy
Cayman Chemical 21059 PD 168393 ≥95% 10mg $184 2024-03-01 Buy

Properties

Melting point :279℃
Boiling point :571.1±50.0 °C(Predicted)
Density :1.558±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO
form :powder
pka :12.19±0.43(Predicted)
color :white to beige
InChI :InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)
InChIKey :HTUBKQUPEREOGA-UHFFFAOYSA-N
SMILES :C(NC1C=CC2C(C=1)=C(NC1=CC=CC(Br)=C1)N=CN=2)(=O)C=C

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

PD 168393 is a potent, irreversible, cell-permeable and selective inhibitor of EGFR (epidermal growth factor receptor). Does not inhibit any other protein kinases. PD 168393 binds to the catalytic domain of the EGFR (EGF receptor tyrosine kinase) with a 1:1 stoichiometry and alkylating Cys773.

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