PELITINIB
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- $40 - $4626
- Product name: PELITINIB
- CAS: 257933-82-7
- MF: C24H23ClFN5O2
- MW: 467.92
- EINECS:803-625-4
- MDL Number:MFCD09837868
- Synonyms:PELITINIB;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide;WAY-EKB 569;(2E)-N-{4-[(3-chloro-4-fluorophenyl)aMino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(diMethylaMino)but-2-enaMide;(E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide;(2e)-n-(4-((3-chloro-4-fluorophenyl)aMino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(diMethylaMino)-2-butenaMide pelitinib;N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)-2(E)-but·Namide
39 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 25mg
- 250mg
- 1000mg
- 1g
- 5
- 25
- 1mg
- 5mg
- 10mg
- 50MG
- 100mg
- 10mM(in 1mL DMSO)
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1141-M001
- Product descriptionPelitinib ≥95%
- Packaging1mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7489
- Product descriptionPelitinib
- Packaging100mg
- Price$267
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111899
- Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
- Packaging5mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111899
- Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
- Packaging10mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111899
- Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
- Packaging100mg
- Price$282
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002397
- Product descriptionPELITINIB 95.00%
- Packaging5MG
- Price$233.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002397
- Product descriptionPELITINIB 95.00%
- Packaging50MG
- Price$2243.59
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1835
- Product descriptionPelitinib(EKB-569)
- Packaging10mM(in 1mL DMSO)
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1835
- Product descriptionPelitinib(EKB-569)
- Packaging100mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS434625
- Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide ≥98%
- Packaging100mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181080
- Product descriptionPelitinib (EKB-569; WAY-EKB 569) >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181080
- Product descriptionPelitinib (EKB-569; WAY-EKB 569) >98%
- Packaging250mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181080
- Product descriptionPelitinib (EKB-569; WAY-EKB 569) >98%
- Packaging1000mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP32643
- Product descriptionPelitinib
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP32643
- Product descriptionPelitinib
- Packaging50mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15627
- Product descriptionPelitinib ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1141-M001 | Pelitinib ≥95% | 1mg | $86 | 2021-12-16 | Buy |
| AK Scientific | X7489 | Pelitinib | 100mg | $267 | 2021-12-16 | Buy |
| Ambeed | A111899 | (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% | 5mg | $40 | 2021-12-16 | Buy |
| Ambeed | A111899 | (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% | 10mg | $59 | 2021-12-16 | Buy |
| Ambeed | A111899 | (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% | 100mg | $282 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002397 | PELITINIB 95.00% | 5MG | $233.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002397 | PELITINIB 95.00% | 50MG | $2243.59 | 2021-12-16 | Buy |
| ApexBio Technology | A1835 | Pelitinib(EKB-569) | 10mM(in 1mL DMSO) | $105 | 2021-12-16 | Buy |
| ApexBio Technology | A1835 | Pelitinib(EKB-569) | 100mg | $640 | 2021-12-16 | Buy |
| Arctom | AS434625 | (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide ≥98% | 100mg | $357 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181080 | Pelitinib (EKB-569; WAY-EKB 569) >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181080 | Pelitinib (EKB-569; WAY-EKB 569) >98% | 250mg | $986 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181080 | Pelitinib (EKB-569; WAY-EKB 569) >98% | 1000mg | $1802 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP32643 | Pelitinib | 10mg | $65 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP32643 | Pelitinib | 50mg | $150 | 2021-12-16 | Buy |
| Cayman Chemical | 15627 | Pelitinib ≥98% | 1mg | $44 | 2024-03-01 | Buy |
Properties
Melting point :173-178°C
Boiling point :655.5±55.0 °C(Predicted)
Density :1.34
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :12.23±0.43(Predicted)
color :white to beige
Boiling point :655.5±55.0 °C(Predicted)
Density :1.34
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :12.23±0.43(Predicted)
color :white to beige
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Pelitinib is a cyanoquinoline that irreversibly inhibits the EGFR receptor tyrosine kinase (IC50 = 39 nM). It inhibits HER2 with a much weaker potency (IC50 = 1.2 μM). By disrupting Akt and MAPK pathways, pelitinib can induce apoptosis and suppress the growth of tumor cell lines, displaying particularly strong efficacy against hepatocellular carcinoma cells (IC50s = ~2 μM).More related product prices
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