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ChemicalBook >> CAS DataBase List >> PFI3

PFI3

PFI3 price.
  • $23 - $1685
  • Product name: PFI3
  • CAS: 1819363-80-8
  • MF: C19H19N3O2
  • MW: 321.37
  • EINECS:
  • MDL Number:MFCD28100807
  • Synonyms:PFI3;(E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one;(2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(2-pyridinyl)-2,5-diazabicyclo[2.2.1]hept-2-yl]-2-propen-1-one;PFI3; PFI 3;CS-1803;(2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one;2-Propen-1-one, 1-(2-hydroxyphenyl)-3-[(1R,4R)-5-(2-pyridinyl)-2,5-diazabicyclo[2.2.1]hept-2-yl]-, (2E)-;PFI3 USP/EP/BP
Price47 Properties Safety Information Description
47 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • AvaChem
  • BroadPharm
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Synthonix
  • Tocris
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 10mM(in1mLDMSO)
  • 5mg
  • 1mg
  • 10
  • 10mM*1mLinDMSO
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 99+%
  • Packaging10mg
  • Price$68
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 94%
  • Packaging50mg
  • Price$182
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 94%
  • Packaging100mg
  • Price$276
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 94%
  • Packaging250mg
  • Price$527
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 94%
  • Packaging500mg
  • Price$828
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 94%
  • Packaging1g
  • Price$1309
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 99+%
  • Packaging5mg
  • Price$45
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABM3
  • Product descriptionPFI-3 99+%
  • Packaging1mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS72369
  • Product descriptionPFI-3 98%
  • Packaging5MG
  • Price$55
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS72369
  • Product descriptionPFI-3 98%
  • Packaging1G
  • Price$1685
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS72369
  • Product descriptionPFI-3 98%
  • Packaging100MG
  • Price$550
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS72369
  • Product descriptionPFI-3 98%
  • Packaging25MG
  • Price$150
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1402DY
  • Product description(E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one
  • Packaging10mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1402DY
  • Product description(E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one
  • Packaging250mg
  • Price$1141
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1402DY
  • Product description(E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one
  • Packaging50mg
  • Price$388
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7744
  • Product descriptionPFI 3
  • Packaging10mg
  • Price$143
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ABM3 PFI-3 99+% 10mg $68 2026-05-28 Buy
aablocks AA00ABM3 PFI-3 94% 50mg $182 2026-05-28 Buy
aablocks AA00ABM3 PFI-3 94% 100mg $276 2026-05-28 Buy
aablocks AA00ABM3 PFI-3 94% 250mg $527 2026-05-28 Buy
aablocks AA00ABM3 PFI-3 94% 500mg $828 2026-05-28 Buy
aablocks AA00ABM3 PFI-3 94% 1g $1309 2026-05-28 Buy
aablocks AA00ABM3 PFI-3 99+% 5mg $45 2026-05-28 Buy
aablocks AA00ABM3 PFI-3 99+% 1mg $23 2026-05-28 Buy
ACHEMBLOCK S72369 PFI-3 98% 5MG $55 2026-05-27 Buy
ACHEMBLOCK S72369 PFI-3 98% 1G $1685 2026-05-27 Buy
ACHEMBLOCK S72369 PFI-3 98% 100MG $550 2026-05-27 Buy
ACHEMBLOCK S72369 PFI-3 98% 25MG $150 2026-05-27 Buy
AK Scientific 1402DY (E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one 10mg $208 2021-12-16 Buy
AK Scientific 1402DY (E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one 250mg $1141 2021-12-16 Buy
AK Scientific 1402DY (E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one 50mg $388 2021-12-16 Buy
ApexBio Technology B7744 PFI 3 10mg $143 2026-05-06 Buy
Next Last

Properties

storage temp. :2-8°C
solubility :Soluble in DMSO (>25 mg/ml)
form :powder
color :yellow to orange
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChI :1S/C19H19N3O2/c23-17-6-2-1-5-16(17)18(24)8-10-21-12-15-11-14(21)13-22(15)19-7-3-4-9-20-19/h1-10,14-15,23H,11-13H2/b10-8+/t14-,15-/m1/s1
InChIKey :INAICWLVUAKEPB-QSTFCLMHSA-N
SMILES :OC1=C(C(/C=C/N2[C@H](C3)CN(C4=NC=CC=C4)[C@H]3C2)=O)C=CC=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The SWI/SNF-related, Matrix-associated, Actin-dependent Regulator of Chromatin (SMARC) proteins integrate into complexes that remodel chromatin. The SMARC family A (SMARCA) members SMARCA2 (also known as BRM) and SMARCA4 (BRG1) are helicases that contain structurally-related bromodomains for binding acetylated lysine residues on target proteins. The protein polybromo-1 (PB1, BRG1-associated factor) contains six bromodomains, but only the fifth (PB1(5)) shares the same structural signature as those of SMARCA2 and SMARCA4. PFI-3 is a probe that binds avidly to the structurally-similar SMARCA4 bromodomain and PB1(bromodomain 5) with Kd values of 89 and 48 nM, respectively. Evaluation of interactions of PFI-3 with different classes of bromodomains using thermal stability assay indicates that PFI-3 interacts selectively with bromodomains from SMARCA2 and SMARCA4 as well as the fifth domain of PB1. Similarly, PFI-1 does not interact with a panel of kinases. See the Structural Genomics Consortium (SGC) website for more information.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
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ROSEWA HOLDING GROUP CO.,LIMITED ShangHai Caerulum Pharma Discovery Co., Ltd. Bide Pharmatech Ltd.