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ChemicalBook >> CAS DataBase List >> PHA-848125

PHA-848125

PHA-848125 price.
  • $62 - $4173.5
  • Product name: PHA-848125
  • CAS: 802539-81-7
  • MF: C25H32N8O
  • MW: 460.57
  • EINECS:-0
  • MDL Number:MFCD17169990
  • Synonyms:PHA-848125;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide;Milciclib;PHA-848125 (Milciclib);Milciclib (PHA-848125);N,1,4,4-tetramethyl-8-(4-(4-methylpiperazin-1-yl)phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide PHA 848125;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]
27 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2.5mg
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberY0330
  • Product descriptionPHA-848125
  • Packaging1mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0330
  • Product descriptionPHA-848125
  • Packaging10mg
  • Price$430
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002463
  • Product descriptionPHA-848125 95.00%
  • Packaging5MG
  • Price$459.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8501
  • Product descriptionPHA-848125
  • Packaging5mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8501
  • Product descriptionPHA-848125
  • Packaging10mM(in 1mL DMSO)
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8501
  • Product descriptionPHA-848125
  • Packaging10mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181086
  • Product descriptionPHA-848125(Milciclib) >98%
  • Packaging100mg
  • Price$1283.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181086
  • Product descriptionPHA-848125(Milciclib) >98%
  • Packaging250mg
  • Price$2097.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181086
  • Product descriptionPHA-848125(Milciclib) >98%
  • Packaging1000mg
  • Price$4173.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21474
  • Product descriptionPHA-848125 ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21474
  • Product descriptionPHA-848125 ≥98%
  • Packaging5mg
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21474
  • Product descriptionPHA-848125
  • Packaging10mg
  • Price$239
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0579
  • Product descriptionMilciclib 99.92%
  • Packaging5mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0579
  • Product descriptionMilciclib 99.92%
  • Packaging10mg
  • Price$396
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0579
  • Product descriptionMilciclib 99.92%
  • Packaging50mg
  • Price$1030
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0579
  • Product descriptionMilciclib 99.92%
  • Packaging100mg
  • Price$1980
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0330 PHA-848125 1mg $166 2021-12-16 Buy
AK Scientific Y0330 PHA-848125 10mg $430 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002463 PHA-848125 95.00% 5MG $459.8 2021-12-16 Buy
ApexBio Technology A8501 PHA-848125 5mg $190 2021-12-16 Buy
ApexBio Technology A8501 PHA-848125 10mM(in 1mL DMSO) $220 2021-12-16 Buy
ApexBio Technology A8501 PHA-848125 10mg $260 2021-12-16 Buy
Biorbyt Ltd orb181086 PHA-848125(Milciclib) >98% 100mg $1283.5 2021-12-16 Buy
Biorbyt Ltd orb181086 PHA-848125(Milciclib) >98% 250mg $2097.8 2021-12-16 Buy
Biorbyt Ltd orb181086 PHA-848125(Milciclib) >98% 1000mg $4173.5 2021-12-16 Buy
Cayman Chemical 21474 PHA-848125 ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 21474 PHA-848125 ≥98% 5mg $135 2024-03-01 Buy
Cayman Chemical 21474 PHA-848125 10mg $239 2024-03-01 Buy
ChemScene CS-0579 Milciclib 99.92% 5mg $240 2021-12-16 Buy
ChemScene CS-0579 Milciclib 99.92% 10mg $396 2021-12-16 Buy
ChemScene CS-0579 Milciclib 99.92% 50mg $1030 2021-12-16 Buy
ChemScene CS-0579 Milciclib 99.92% 100mg $1980 2021-12-16 Buy

Properties

Melting point :190 °C
Density :1.33
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :14.44±0.40(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PHA-848125 is an ATP-competitive inhibitor of cyclin-dependent kinases (Cdks) that potently inhibits Cdk2/cyclin A (IC50 = 45 nM). It is at least 3-fold less potent at Cdks 1, 3, 4, 5, and 7. PHA-848125 is orally available and displays efficacy in suppressing the growth of cancer cells or tumor xenografts in animals.