PHA-848125
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- $55 - $4173.5
- Product name: PHA-848125
- CAS: 802539-81-7
- MF: C25H32N8O
- MW: 460.57
- EINECS:-0
- MDL Number:MFCD17169990
- Synonyms:PHA-848125;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide;Milciclib;PHA-848125 (Milciclib);Milciclib (PHA-848125);N,1,4,4-tetramethyl-8-(4-(4-methylpiperazin-1-yl)phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide PHA 848125;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]
53 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 50mg
- 250mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 5MG
- 10mM*1mLinDMSO(Solution)
- 5g
- 10mM*1mLinDMSO
- 1000mg
- 1mg
- 2.5mg
- 10mg
- 10mM(in1mLDMSO)
- 25MG
- 100MG
- 1G
- 10mM(in 1mL DMSO)
- ManufacturerACHEMBLOCK
- Product numberA-627
- Product descriptionPHA-848125 98%
- Packaging5MG
- Price$55
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberA-627
- Product descriptionPHA-848125 98%
- Packaging25MG
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberA-627
- Product descriptionPHA-848125 98%
- Packaging100MG
- Price$395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberA-627
- Product descriptionPHA-848125 98%
- Packaging1G
- Price$1800
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0330
- Product descriptionPHA-848125
- Packaging10mg
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0330
- Product descriptionPHA-848125
- Packaging1mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002463
- Product descriptionPHA-848125 95.00%
- Packaging5MG
- Price$459.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging10mg
- Price$270
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging10mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging5mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging5mg
- Price$200
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging10mM(in 1mL DMSO)
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging10mM(in1mLDMSO)
- Price$220
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-10424
- Product descriptionMilciclib 99.90%
- Packaging10mg
- Price$217
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10424
- Product descriptionMilciclib 99.90%
- Packaging10mM*1mLinDMSO(Solution)
- Price$131
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10424
- Product descriptionMilciclib 99.90%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$124
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | A-627 | PHA-848125 98% | 5MG | $55 | 2026-05-27 | Buy |
| ACHEMBLOCK | A-627 | PHA-848125 98% | 25MG | $160 | 2026-05-27 | Buy |
| ACHEMBLOCK | A-627 | PHA-848125 98% | 100MG | $395 | 2026-05-27 | Buy |
| ACHEMBLOCK | A-627 | PHA-848125 98% | 1G | $1800 | 2026-05-27 | Buy |
| AK Scientific | Y0330 | PHA-848125 | 10mg | $430 | 2021-12-16 | Buy |
| AK Scientific | Y0330 | PHA-848125 | 1mg | $166 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002463 | PHA-848125 95.00% | 5MG | $459.8 | 2021-12-16 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 10mg | $270 | 2026-05-06 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 10mg | $260 | 2021-12-16 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 5mg | $190 | 2021-12-16 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 5mg | $200 | 2026-05-06 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 10mM(in 1mL DMSO) | $220 | 2021-12-16 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 10mM(in1mLDMSO) | $220 | 2026-05-06 | Buy |
| Arctom | HY-10424 | Milciclib 99.90% | 10mg | $217 | 2026-05-26 | Buy |
| Arctom | HY-10424 | Milciclib 99.90% | 10mM*1mLinDMSO(Solution) | $131 | 2026-05-26 | Buy |
| Arctom | HY-10424 | Milciclib 99.90% | 10mM*1mLinDMSO(Solid+Solvent) | $124 | 2026-05-26 | Buy |
Properties
Melting point :190 °C
Density :1.33
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :14.44±0.40(Predicted)
color :Light yellow to yellow
InChIKey :RXZMYLDMFYNEIM-UHFFFAOYSA-N
SMILES :N1=C2C(CC(C)(C)C3C(C(NC)=O)=NN(C)C=32)=CN=C1NC1=CC=C(N2CCN(C)CC2)C=C1
Density :1.33
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :14.44±0.40(Predicted)
color :Light yellow to yellow
InChIKey :RXZMYLDMFYNEIM-UHFFFAOYSA-N
SMILES :N1=C2C(CC(C)(C)C3C(C(NC)=O)=NN(C)C=32)=CN=C1NC1=CC=C(N2CCN(C)CC2)C=C1
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
PHA-848125 is an ATP-competitive inhibitor of cyclin-dependent kinases (Cdks) that potently inhibits Cdk2/cyclin A (IC50 = 45 nM). It is at least 3-fold less potent at Cdks 1, 3, 4, 5, and 7. PHA-848125 is orally available and displays efficacy in suppressing the growth of cancer cells or tumor xenografts in animals.Related product price
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