PI3K inhibitor
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- $116 - $2084
- Product name: PI3K inhibitor
- CAS: 1202884-94-3
- MF: C31H35F3N8O3
- MW: 624.66
- EINECS:-0
- MDL Number:MFCD18251469
- Synonyms:PI3K inhibitor;Antitumor Drug;CAY10626;BenzaMide, N-[2-(diMethylaMino)ethyl]-N-Methyl-4-[[[[4-[4-(4-Morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyriMidin-2-yl]phenyl]aMino]carbonyl]aMino]-;N-[2-(dimethylamino)ethyl]-N-methyl-4-[({4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl}carbamoyl)amino]benzamide;PI3K-IN-22;CAY10626, PI3Kalpha/mTOR inhibitor
12 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- TRC
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- Manufactureraablocks
- Product numberAA008SOQ
- Product descriptionCAY10626 ≥98%
- Packaging1mg
- Price$116
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SOQ
- Product descriptionCAY10626 ≥98%
- Packaging5mg
- Price$521
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SOQ
- Product descriptionCAY10626 ≥98%
- Packaging25mg
- Price$1877
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number3628DF
- Product descriptionN-[2-(Dimethylamino)ethyl]-N-methyl-4-[[4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)pyrrolo[2,3-d]pyrimidin-2-yl]phenyl]carbamoylamino]benzamide
- Packaging25mg
- Price$2084
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3628DF
- Product descriptionN-[2-(Dimethylamino)ethyl]-N-methyl-4-[[4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)pyrrolo[2,3-d]pyrimidin-2-yl]phenyl]carbamoylamino]benzamide
- Packaging10mg
- Price$1007
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0316610
- Product descriptionN-[2-(DIMETHYLAMINO)ETHYL]-N-METHYL-4-[[[[4-[4-(4-MORPHOLINYL)-7-(2,2,2-TRIFLUOROETHYL)-7H-PYRROLO-[2,3-D]PYRIMIDIN-2-YL]PHENYL]AMINO]CARBONYL]AMINO]-BENZAMIDE 95.00%
- Packaging5MG
- Price$495.61
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13838
- Product descriptionCAY10626 ≥98%
- Packaging5mg
- Price$521
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number13838
- Product descriptionCAY10626 ≥98%
- Packaging25mg
- Price$1877
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number13838
- Product descriptionCAY10626 ≥98%
- Packaging10mg
- Price$924
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number13838
- Product descriptionCAY10626 ≥98%
- Packaging1mg
- Price$116
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0002681
- Product descriptionPI3K-IN-22 99.50%
- Packaging1mg
- Price$265
- Updated2026-06-04
- Buy
- ManufacturerTRC
- Product numberC227025
- Product descriptionCAY10626
- Packaging2.5mg
- Price$295
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008SOQ | CAY10626 ≥98% | 1mg | $116 | 2026-05-28 | Buy |
| aablocks | AA008SOQ | CAY10626 ≥98% | 5mg | $521 | 2026-05-28 | Buy |
| aablocks | AA008SOQ | CAY10626 ≥98% | 25mg | $1877 | 2026-05-28 | Buy |
| AK Scientific | 3628DF | N-[2-(Dimethylamino)ethyl]-N-methyl-4-[[4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)pyrrolo[2,3-d]pyrimidin-2-yl]phenyl]carbamoylamino]benzamide | 25mg | $2084 | 2021-12-16 | Buy |
| AK Scientific | 3628DF | N-[2-(Dimethylamino)ethyl]-N-methyl-4-[[4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)pyrrolo[2,3-d]pyrimidin-2-yl]phenyl]carbamoylamino]benzamide | 10mg | $1007 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0316610 | N-[2-(DIMETHYLAMINO)ETHYL]-N-METHYL-4-[[[[4-[4-(4-MORPHOLINYL)-7-(2,2,2-TRIFLUOROETHYL)-7H-PYRROLO-[2,3-D]PYRIMIDIN-2-YL]PHENYL]AMINO]CARBONYL]AMINO]-BENZAMIDE 95.00% | 5MG | $495.61 | 2021-12-16 | Buy |
| Cayman Chemical | 13838 | CAY10626 ≥98% | 5mg | $521 | 2026-04-30 | Buy |
| Cayman Chemical | 13838 | CAY10626 ≥98% | 25mg | $1877 | 2026-04-30 | Buy |
| Cayman Chemical | 13838 | CAY10626 ≥98% | 10mg | $924 | 2026-04-30 | Buy |
| Cayman Chemical | 13838 | CAY10626 ≥98% | 1mg | $116 | 2026-04-30 | Buy |
| ChemScene | CS-0002681 | PI3K-IN-22 99.50% | 1mg | $265 | 2026-06-04 | Buy |
| TRC | C227025 | CAY10626 | 2.5mg | $295 | 2021-12-16 | Buy |
Properties
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 15 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
form :A crystalline solid
pka :13.74±0.70(Predicted)
color :White to light yellow
storage temp. :Store at -20°C
solubility :DMF: 15 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
form :A crystalline solid
pka :13.74±0.70(Predicted)
color :White to light yellow
Safety Information
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Description
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3, important second messengers that modulate the activity of downstream targets Akt and mTOR. Aberrant PI3K/Akt is associated with many human cancers. CAY10626 is a potent, dual PI3Kα/mTOR inhibitor with IC50 values of 0.9 and 0.6 nM for the two respective kinases. In a tumor cell growth inhibition assay, CAY10626 demonstrates IC50 values of <3 and 13 nM for MDA361 (breast) and PC3 (prostate) cancer cell lines, respectively. When administered at 25-50 mg/k to MD361 xenograft mice, phosphorylation of the downstream targets of PI3Kα and mTOR (Akt T308, Akt S473, and S6K) was suppressed, and significant tumor regression was observed.More related product prices
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