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ChemicalBook >> CAS DataBase List >> PKSI 527

PKSI 527

PKSI 527 price.
  • $83 - $1257
  • Product name: PKSI 527
  • CAS: 128837-71-8
  • MF: C25H31N3O4.ClH
  • MW: 473.998
  • EINECS:
  • MDL Number:MFCD01745772
  • Synonyms:2-[4-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]aceticacid,hydrochloride;PKSI 527,PKSI527;2-(4-((S)-2-(trans-4-(Aminomethyl)cyclohexane-1-carboxamido)-3-phenylpropanamido)phenyl)acetic acid hydrochloride;Benzeneacetic acid, 4-[[(2S)-2-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-, hydrochloride (1:1);PKSI-527, plasma kallikrein inhibitor
18 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • Cayman Chemical
Package
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • Manufactureraablocks
  • Product numberAA000YC5
  • Product descriptionPKSI-527 ≥95%
  • Packaging5mg
  • Price$83
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000YC5
  • Product descriptionPKSI-527 ≥95%
  • Packaging25mg
  • Price$330
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000YC5
  • Product descriptionPKSI-527 97%
  • Packaging50mg
  • Price$338
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000YC5
  • Product descriptionPKSI-527 97%
  • Packaging100mg
  • Price$542
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000YC5
  • Product descriptionPKSI-527 97%
  • Packaging250mg
  • Price$1257
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product number6192CJ
  • Product description2-[4-[[(2S)-2-[[4-(Aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]aceticacid;hydrochloride
  • Packaging5mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000084
  • Product descriptionPKSI-527 95.00%
  • Packaging5MG
  • Price$503.38
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-123133
  • Product descriptionPKSI-527 98.04%
  • Packaging25mg
  • Price$380
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-123133
  • Product descriptionPKSI-527 98.04%
  • Packaging50mg
  • Price$608
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-123133
  • Product descriptionPKSI-527 98.04%
  • Packaging100mg
  • Price$974
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-123133
  • Product descriptionPKSI-527 98.04%
  • Packaging10mg
  • Price$181
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-123133
  • Product descriptionPKSI-527 98.04%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$104
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-123133
  • Product descriptionPKSI-527 98.04%
  • Packaging5mg
  • Price$105
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-123133
  • Product descriptionPKSI-527 98.04%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$110
  • Updated2026-05-26
  • Buy
  • ManufacturerCayman Chemical
  • Product number23974
  • Product descriptionPKSI-527 ≥95%
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23974
  • Product descriptionPKSI-527 ≥95%
  • Packaging5mg
  • Price$83
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000YC5 PKSI-527 ≥95% 5mg $83 2026-05-25 Buy
aablocks AA000YC5 PKSI-527 ≥95% 25mg $330 2026-05-25 Buy
aablocks AA000YC5 PKSI-527 97% 50mg $338 2026-05-25 Buy
aablocks AA000YC5 PKSI-527 97% 100mg $542 2026-05-25 Buy
aablocks AA000YC5 PKSI-527 97% 250mg $1257 2026-05-25 Buy
AK Scientific 6192CJ 2-[4-[[(2S)-2-[[4-(Aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]aceticacid;hydrochloride 5mg $233 2021-12-16 Buy
American Custom Chemicals Corporation INB0000084 PKSI-527 95.00% 5MG $503.38 2021-12-16 Buy
Arctom HY-123133 PKSI-527 98.04% 25mg $380 2026-05-26 Buy
Arctom HY-123133 PKSI-527 98.04% 50mg $608 2026-05-26 Buy
Arctom HY-123133 PKSI-527 98.04% 100mg $974 2026-05-26 Buy
Arctom HY-123133 PKSI-527 98.04% 10mg $181 2026-05-26 Buy
Arctom HY-123133 PKSI-527 98.04% 10mM*1mLinDMSO(Solid+Solvent) $104 2026-05-26 Buy
Arctom HY-123133 PKSI-527 98.04% 5mg $105 2026-05-26 Buy
Arctom HY-123133 PKSI-527 98.04% 10mM*1mLinDMSO(Solution) $110 2026-05-26 Buy
Cayman Chemical 23974 PKSI-527 ≥95% 5mg $121 2024-03-01 Buy
Cayman Chemical 23974 PKSI-527 ≥95% 5mg $83 2026-04-30 Buy

Properties

storage temp. :-20°C
solubility :Soluble in Water (5 mg/ml)
form :White solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

PKSI-527 is a highly selective plasma kallikrein inhibitor (Ki = 0.81 μM) which can be used for affinity purification of kalikrein. It suppresses collagen-induced arthritis in a mouse model. Additionally, PKSI-527 has been shown to synergize with NO donors producing antithrombotic effects.

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