Welcome to chemicalbook!
010-86108875
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> POLYPHYLLIN D

POLYPHYLLIN D

POLYPHYLLIN D price.
  • $60 - $795
  • Product name: POLYPHYLLIN D
  • CAS: 50773-41-6
  • MF: C44H70O16
  • MW: 855.02
  • EINECS:
  • MDL Number:MFCD12407435
  • Synonyms:POLYPHYLLIN D;Paris saponin Pa;Paris I;I,Chonglousaponin;Polyphyllin I(Chonglou Saponin I);Polyphyllin D / Diosgenyl 4-O-α-L-arabinofuranosyl-2-O-α-L-rhamnopyranosyl-β -D-glucopyranoside;Polyphyllin I, 98%, from Paris polyphylla Smith var.chinensis;GLYCO-DIOSGENIN
49 prices
Selected condition:
Brand
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Frontier Specialty Chemicals
  • JR MediChem
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 10mg
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 500mg
  • 1000mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5MG
  • 20mg
  • 25mg
  • 50MG
  • 100MG
  • ManufacturerACHEMBLOCK
  • Product numberU106763
  • Product descriptionPolyphyllin I 98.00%
  • Packaging50MG
  • Price$125
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU106763
  • Product descriptionPolyphyllin I 98.00%
  • Packaging100MG
  • Price$210
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberW2667
  • Product descriptionChonglouSaponinI
  • Packaging100mg
  • Price$455
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0000179
  • Product descriptionPOLYPHYLLIN I 95.00%
  • Packaging5MG
  • Price$501.34
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1924
  • Product descriptionPolyphyllin A
  • Packaging20mg
  • Price$207
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1924
  • Product descriptionPolyphyllinA
  • Packaging20mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-N0047
  • Product descriptionPolyphyllin I 99.89%
  • Packaging25mg
  • Price$190
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-N0047
  • Product descriptionPolyphyllin I 99.89%
  • Packaging50mg
  • Price$285
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-N0047
  • Product descriptionPolyphyllin I 99.89%
  • Packaging100mg
  • Price$456
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-N0047
  • Product descriptionPolyphyllin I 99.89%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$113
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-N0047
  • Product descriptionPolyphyllin I 99.89%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$118
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-N0047
  • Product descriptionPolyphyllin I 99.89%
  • Packaging5mg
  • Price$63
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-N0047
  • Product descriptionPolyphyllin I 99.89%
  • Packaging10mg
  • Price$105
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S9114
  • Product descriptionPolyphyllin I 99.85%
  • Packaging1mg
  • Price$140
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberAB0760
  • Product descriptionPolyphyllin I 98%(HPLC)
  • Packaging20mg
  • Price$158
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberAB0760
  • Product descriptionPolyphyllin I 98%(HPLC)
  • Packaging1000mg
  • Price$680
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK U106763 Polyphyllin I 98.00% 50MG $125 2026-05-27 Buy
ACHEMBLOCK U106763 Polyphyllin I 98.00% 100MG $210 2026-05-27 Buy
AK Scientific W2667 ChonglouSaponinI 100mg $455 2021-12-16 Buy
American Custom Chemicals Corporation PXT0000179 POLYPHYLLIN I 95.00% 5MG $501.34 2021-12-16 Buy
ApexBio Technology N1924 Polyphyllin A 20mg $207 2026-05-06 Buy
ApexBio Technology N1924 PolyphyllinA 20mg $250 2021-12-16 Buy
Arctom HY-N0047 Polyphyllin I 99.89% 25mg $190 2026-05-26 Buy
Arctom HY-N0047 Polyphyllin I 99.89% 50mg $285 2026-05-26 Buy
Arctom HY-N0047 Polyphyllin I 99.89% 100mg $456 2026-05-26 Buy
Arctom HY-N0047 Polyphyllin I 99.89% 10mM*1mLinDMSO(Solid+Solvent) $113 2026-05-26 Buy
Arctom HY-N0047 Polyphyllin I 99.89% 10mM*1mLinDMSO(Solution) $118 2026-05-26 Buy
Arctom HY-N0047 Polyphyllin I 99.89% 5mg $63 2026-05-26 Buy
Arctom HY-N0047 Polyphyllin I 99.89% 10mg $105 2026-05-26 Buy
Arctom SLK-S9114 Polyphyllin I 99.85% 1mg $140 2026-05-26 Buy
Arctom AB0760 Polyphyllin I 98%(HPLC) 20mg $158 2026-05-26 Buy
Arctom AB0760 Polyphyllin I 98%(HPLC) 1000mg $680 2026-05-26 Buy

Properties

Melting point :>245°C (dec.)
Density :1.40
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly)
pka :12+-.0.70(Predicted)
form :Solid
color :White
Major Application :food and beverages
pharmaceutical InChIKey :LRRDDWMXYOSKIC-IPKCVOQPSA-N

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Polyphyllin I is a steroid saponin that has been found in P. polyphylla and has anticancer activity. It decreases proliferation of, and induces apoptosis in, MCF-7 and MDA-MB-231 cells (IC50s = 5 and 2.5 μM, respectively). It disrupts the mitochondrial membrane potential, activates caspase-3, and increases protein levels of the caspase-3 substrate poly(ADP-ribose) polymerase (PARP) in HepG2 and drug-resistant R-HepG2 cells. Polyphyllin I (2.05 and 2.73 mg/kg for 10 days) reduces tumor growth in an MCF-7 mouse xenograft model.