PRL-3 INHIBITOR I
![]() |
- $32 - $663.07
- Product name: PRL-3 INHIBITOR I
- CAS: 893449-38-2
- MF: C17H11Br2NO2S2
- MW: 485.21
- EINECS:
- MDL Number:MFCD11045303
- Synonyms:PRL-3 INHIBITOR I;Phosphatase of regenerating liver-3, Inhibitor I, 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone;5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone;Phosphatase of regenerating liver-3, Inhibitor I;PRL-3 Inhibitor;PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem;5-(5-Bromo-2-((2-bromobenzyl)oxy)benzylidene)-2-thioxothiazolidin-4-one;P0180
13 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 25mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000809
- Product descriptionPRL-3 INHIBITOR I 95.00%
- Packaging5MG
- Price$663.07
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3996
- Product descriptionPRL-3Inhibitor
- Packaging5mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3996
- Product descriptionPRL-3Inhibitor
- Packaging10mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3996
- Product descriptionPRL-3Inhibitor
- Packaging25mg
- Price$477
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3436
- Product descriptionPRL-3inhibitor-BR1 98%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18719
- Product descriptionPRL-3 Inhibitor ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18719
- Product descriptionPRL-3 Inhibitor ≥98%
- Packaging5mg
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18719
- Product descriptionPRL-3 Inhibitor ≥98%
- Packaging10mg
- Price$122
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18719
- Product descriptionPRL-3 Inhibitor ≥98%
- Packaging25mg
- Price$267
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0108
- Product descriptionPRL-3 Inhibitor I ≥98% (HPLC), solid
- Packaging5mg
- Price$105
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberB680650
- Product description5-[[5-Bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB680650
- Product description5-[[5-Bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone
- Packaging25mg
- Price$335
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number349626
- Product descriptionPRL-3 Inhibitor
- Packaging1mg
- Price$247
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | INB0000809 | PRL-3 INHIBITOR I 95.00% | 5MG | $663.07 | 2021-12-16 | Buy |
ApexBio Technology | C3996 | PRL-3Inhibitor | 5mg | $112 | 2021-12-16 | Buy |
ApexBio Technology | C3996 | PRL-3Inhibitor | 10mg | $208 | 2021-12-16 | Buy |
ApexBio Technology | C3996 | PRL-3Inhibitor | 25mg | $477 | 2021-12-16 | Buy |
Axon Medchem | Axon3436 | PRL-3inhibitor-BR1 98% | 10mg | $99 | 2021-12-16 | Buy |
Cayman Chemical | 18719 | PRL-3 Inhibitor ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 18719 | PRL-3 Inhibitor ≥98% | 5mg | $70 | 2024-03-01 | Buy |
Cayman Chemical | 18719 | PRL-3 Inhibitor ≥98% | 10mg | $122 | 2024-03-01 | Buy |
Cayman Chemical | 18719 | PRL-3 Inhibitor ≥98% | 25mg | $267 | 2024-03-01 | Buy |
Sigma-Aldrich | P0108 | PRL-3 Inhibitor I ≥98% (HPLC), solid | 5mg | $105 | 2024-03-01 | Buy |
TRC | B680650 | 5-[[5-Bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone | 5mg | $80 | 2021-12-16 | Buy |
TRC | B680650 | 5-[[5-Bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone | 25mg | $335 | 2021-12-16 | Buy |
Usbiological | 349626 | PRL-3 Inhibitor | 1mg | $247 | 2021-12-16 | Buy |
Properties
Density :1.85±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :7.11±0.50(Predicted)
color :yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
storage temp. :−20°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :7.11±0.50(Predicted)
color :yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
Symbol(GHS): |
![]() ![]() |
|||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Phosphatase of regenerating liver 3 (PRL-3; also known as PTP4A3) plays critical roles in cell proliferation, motility, and invasion, and thus contributes to cancer metastasis. PRL-3 inhibitor is a cell-permeable benzylidene rhodamine that inhibits PRL-3 (IC50 = 900 nM for human PRL-3 in vitro), with minimal activity against other phosphatases. It reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay. PRL-3 inhibitor has been used to elucidate the actions of this enzyme, demonstrating that it dephosphorylates Tyr783 on integrin β1 and modulates VEGF-mediated endothelial cell migration. It dose-dependently inhibits the growth and triggers apoptosis in cancer cell lines.Related product price
- AAL-993
$73-1450 - 115104-28-4
$32-860 - CL 82198 HYDROCHLORIDE
$40-1732.75
Suppliers and manufacturers
InvivoChem
Nanjing Doge Biomedical Technology Co., Ltd
LEAPCHEM CO., LTD.
Aladdin Scientific
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Shanghai SuperLan Chemcial Technique Centre