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ChemicalBook >> CAS DataBase List >> Pidotimod

Pidotimod

Pidotimod price.
  • $5 - $2055.9
  • Product name: Pidotimod
  • CAS: 121808-62-6
  • MF: C9H12N2O4S
  • MW: 244.27
  • EINECS:2017-001-1
  • MDL Number:MFCD00867583
  • Synonyms:(4R)-3-[(2S)-5-Oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid;(4S)-3-(5-Oxo-L-prolyl)thiazolidine-4-carboxylic acid;3-Pyroglutamoylthiazolidine-4-carboxylic acid;(4R)-3-[(2S)-5-ketopyrrolidine-2-carbonyl]thiazolidine-4-carboxylic acid;(4R)-3-[(2S)-5-oxopyrrolidin-2-yl]carbonyl-1,3-thiazolidine-4-carboxylic acid;(R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid;Axil;Onaka
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  • ManufacturerAHH
  • Product numberMT-57996
  • Product descriptionPidotimod 98%
  • Packaging10g
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberO230
  • Product descriptionPidotimod
  • Packaging1g
  • Price$25
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA147731
  • Product descriptionPidotimod 98+%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA147731
  • Product descriptionPidotimod 98+%
  • Packaging1g
  • Price$12
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA147731
  • Product descriptionPidotimod 98+%
  • Packaging5g
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147731
  • Product descriptionPidotimod 98+%
  • Packaging10g
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147731
  • Product descriptionPidotimod 98+%
  • Packaging25g
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147731
  • Product descriptionPidotimod 98+%
  • Packaging100g
  • Price$345
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003845
  • Product descriptionPIDOTIMOD 95.00%
  • Packaging1G
  • Price$426.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003845
  • Product descriptionPIDOTIMOD 95.00%
  • Packaging10G
  • Price$2055.9
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS008513
  • Product descriptionPidotimod ≥98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS008513
  • Product descriptionPidotimod ≥98%
  • Packaging1g
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008513
  • Product descriptionPidotimod ≥98%
  • Packaging5g
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008513
  • Product descriptionPidotimod ≥98%
  • Packaging10g
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008513
  • Product descriptionPidotimod ≥98%
  • Packaging25g
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS008513
  • Product descriptionPidotimod ≥98%
  • Packaging100g
  • Price$342
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-57996 Pidotimod 98% 10g $310 2021-12-16 Buy
AK Scientific O230 Pidotimod 1g $25 2021-12-16 Buy
Ambeed A147731 Pidotimod 98+% 100mg $5 2021-12-16 Buy
Ambeed A147731 Pidotimod 98+% 1g $12 2021-12-16 Buy
Ambeed A147731 Pidotimod 98+% 5g $34 2021-12-16 Buy
Ambeed A147731 Pidotimod 98+% 10g $57 2021-12-16 Buy
Ambeed A147731 Pidotimod 98+% 25g $115 2021-12-16 Buy
Ambeed A147731 Pidotimod 98+% 100g $345 2021-12-16 Buy
American Custom Chemicals Corporation API0003845 PIDOTIMOD 95.00% 1G $426.3 2021-12-16 Buy
American Custom Chemicals Corporation API0003845 PIDOTIMOD 95.00% 10G $2055.9 2021-12-16 Buy
Arctom AS008513 Pidotimod ≥98% 100mg $5 2021-12-16 Buy
Arctom AS008513 Pidotimod ≥98% 1g $12 2021-12-16 Buy
Arctom AS008513 Pidotimod ≥98% 5g $34 2021-12-16 Buy
Arctom AS008513 Pidotimod ≥98% 10g $56 2021-12-16 Buy
Arctom AS008513 Pidotimod ≥98% 25g $114 2021-12-16 Buy
Arctom AS008513 Pidotimod ≥98% 100g $342 2021-12-16 Buy

Properties

Melting point :194-198°C (dec.)
alpha :D25 -150° (c = 2 in 5N HCl)
Boiling point :663.0±55.0 °C(Predicted)
Density :1.53
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated), 5N HCl (Slightly)
form :powder
pka :3.03(at 25℃)
color :white to beige
optical activity :[α]/D -135 to -155°, c = 1 in 6 M HCl
Merck :14,7419
InChI :InChI=1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1
InChIKey :UUTKICFRNVKFRG-WDSKDSINSA-N
SMILES :S1C[C@@H](C(O)=O)N(C([C@@H]2CCC(=O)N2)=O)C1
CAS DataBase Reference :121808-62-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Pidotimod is a synthetic dipeptide with immunomodulatory properties on both innate and adaptive immune responses in in vitro studies. It has been shown to induce dendritic cell (DC) maturation, to upregulate the expression of HLA-DR and co-stimulatory molecules CD83 and CD86, to stimulate the release of pro-inflammatory molecules from DCs, which drives T cell proliferation and differentiation towards a Th1 phenotype, to enhance natural killer cell functions, to inhibit thymocyte apoptosis, and to promote phagocytosis. Through separate effects on ERK1/2 and NF-κB, pidotimod was shown to increase the expression of toll-like receptor 2 proteins. Pimotimod does not affect expression of ICAM-1 or the release of IL-8.

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