Protectin D1
|
- $121 - $903
- Product name: Protectin D1
- CAS: 660430-03-5
- MF: C22H32O4
- MW: 360.49
- EINECS:
- MDL Number:
- Synonyms:Protectin D1;4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-;NPD1;Protectin D-1,Protectin D1
4 prices
Selected condition：
Brand
- Cayman Chemical
Package
- 10μg
- 25μg
- 50μg
- 100μg
- ManufacturerCayman Chemical
- Product number10010390
- Product descriptionProtectin D1 ≥98%
- Packaging10μg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010390
- Product descriptionProtectin D1 ≥98%
- Packaging25μg
- Price$273
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010390
- Product descriptionProtectin D1 ≥98%
- Packaging50μg
- Price$513
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010390
- Product descriptionProtectin D1 ≥98%
- Packaging100μg
- Price$903
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 10010390 | Protectin D1 ≥98% | 10μg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 10010390 | Protectin D1 ≥98% | 25μg | $273 | 2024-03-01 | Buy |
| Cayman Chemical | 10010390 | Protectin D1 ≥98% | 50μg | $513 | 2024-03-01 | Buy |
| Cayman Chemical | 10010390 | Protectin D1 ≥98% | 100μg | $903 | 2024-03-01 | Buy |
Properties
Boiling point :559.4±50.0 °C(Predicted)
Density :1.048±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form :Liquid
pka :4.58±0.10(Predicted)
color :Colorless to light yellow
Density :1.048±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form :Liquid
pka :4.58±0.10(Predicted)
color :Colorless to light yellow
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; ). DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to protectin D1 enzymatically. Protectin D1 increases phagocytosis of apoptotic polymorphonuclear leukocytes (PMNs) by macrophages in a non-phlogistic manner and is generated in vitro during macrophage-apoptotic interactions. It enhances phagocytosis in mice after 24 hours, but not at the initiation or peak of inflammation. It also decreases PMN infiltration in a zymosan-induced mouse model of inflammation when administered at a dose of 300 ng per animal. Protectin D1 (200 μg, i.v.) inhibits increases in neutrophil counts in bronchoalveolar fluid (BALF) and lung myeloperoxidase activity in a mouse model of pulmonary injury and inflammation induced by intratracheal LPS instillation. It also decreases pulmonary edema and promotes neutrophil apoptosis in BALF.Suppliers and manufacturers
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
amyjet
Beijing Biocreative Technology Co., Ltd.
Shanghai Yifei Biotechnology Co. , Ltd.
TargetMol Chemicals Inc.
Sangon Biotech (Shanghai) Co.,Ltd.
Cayman Chemical Company
Biosynth Biological Technology (Suzhou) Co Ltd
