RP 001 (hydrochloride)
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- $37 - $975
- Product name: RP 001 (hydrochloride)
- CAS: 1781880-34-9
- MF: C24H25ClN4O4
- MW: 468.94
- EINECS:
- MDL Number:
- Synonyms:RP001 hydrochloride,RP 001 hydrochloride;N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
7 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number4509EB
- Product descriptionRP001hydrochloride
- Packaging1mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4509EB
- Product descriptionRP001hydrochloride
- Packaging10mg
- Price$374
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16636
- Product descriptionRP 001 (hydrochloride) ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16636
- Product descriptionRP 001 (hydrochloride) ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16636
- Product descriptionRP 001 (hydrochloride) ≥98%
- Packaging10mg
- Price$249
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16636
- Product descriptionRP 001 (hydrochloride) ≥98%
- Packaging25mg
- Price$530
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberR700988
- Product descriptionRP001Hydrochloride
- Packaging50mg
- Price$975
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4509EB | RP001hydrochloride | 1mg | $139 | 2021-12-16 | Buy |
| AK Scientific | 4509EB | RP001hydrochloride | 10mg | $374 | 2021-12-16 | Buy |
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 10mg | $249 | 2024-03-01 | Buy |
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 25mg | $530 | 2024-03-01 | Buy |
| TRC | R700988 | RP001Hydrochloride | 50mg | $975 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO: 100 mM
form :A solid
color :White to off-white
solubility :DMSO: 100 mM
form :A solid
color :White to off-white
Safety Information
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Description
RP 001 is a potent sphingosine-1-phosphate receptor 1 (S1P1) agonist (EC50 = 9 pM). It is competitive with W146 , a selective S1P1 antagonist, and induces internalization and polyubiquitination of S1P1 in a dose-dependent manner. RP 001 induces dose-dependent lymphopenia in mice (EC50 = 0.03 mg/kg). It reduces S1P1-EGFP expression ex vivo on lymphocytes in the isolated lymph node of Edg1eGFP/eGFP mice but has no effect in vivo. RP 001 also completely inhibits M. stadtmanae (MSS) rechallenge-induced enlargement of B cell-rich tertiary lymphoid tissues (TLTs) and reduces neutrophil accumulation in the airways of a mouse model of experimental hypersensitivity pneumonitis.Suppliers and manufacturers
TargetMol Chemicals Inc.
Aladdin Scientific
Shanghai EFE Biological Technology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Changzhou Furuisi Biotechnology Co., Ltd
TargetMol Chemicals Inc.
R&D Systems, Inc
Cayman Chemical Company
Biosynth Biological Technology (Suzhou) Co Ltd
