Rbin-1
|
- $93 - $2200
- Product name: Rbin-1
- CAS: 328023-11-6
- MF: C13H12N4S
- MW: 256.33
- EINECS:-0
- MDL Number:MFCD02369534
- Synonyms:Rbin-1;3-(2-methylprop-2-enylsulfanyl)-5H-[1,2,4]triazino[5,6-b]indole;Rbin-1 - Ribozinoindole-1;RBIN 1;RIBOZINOINDOLE 1;RBIN1;RIBOZINOINDOLE-1;RBIN-1;RIBOZINOINDOLE1;Ribozinoindole 1;Ribozinoindole1;Ribozinoindole-1;CS-2565
18 prices
Selected condition:
Brand
- AK Scientific
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number3319CP
- Product description3-(2-Methylprop-2-enylsulfanyl)-5H-[1,2,4]triazino[5,6-b]indole
- Packaging1mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2663
- Product descriptionRbin-1-Ribozinoindole-1 99%
- Packaging10mg
- Price$137.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2663
- Product descriptionRbin-1-Ribozinoindole-1 99%
- Packaging50mg
- Price$522.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20745
- Product descriptionRbin-1 ≥98%
- Packaging1mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20745
- Product descriptionRbin-1 ≥98%
- Packaging5mg
- Price$388
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-6068
- Product descriptionRbin-1 99.91%
- Packaging1mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6068
- Product descriptionRbin-1 99.91%
- Packaging5mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6068
- Product descriptionRbin-1 99.91%
- Packaging10mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6068
- Product descriptionRbin-1 99.91%
- Packaging25mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6068
- Product descriptionRbin-1 99.91%
- Packaging50mg
- Price$1500
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6068
- Product descriptionRbin-1 99.91%
- Packaging100mg
- Price$2100
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11144576
- Product descriptionRbin-1 97%
- Packaging5mg
- Price$339
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11144576
- Product descriptionRbin-1 97%
- Packaging10mg
- Price$513
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11144576
- Product descriptionRbin-1 97%
- Packaging25mg
- Price$1026
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11144576
- Product descriptionRbin-1 97%
- Packaging50mg
- Price$1538
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC11468
- Product descriptionRbin-1 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3319CP | 3-(2-Methylprop-2-enylsulfanyl)-5H-[1,2,4]triazino[5,6-b]indole | 1mg | $201 | 2021-12-16 | Buy |
| Axon Medchem | Axon2663 | Rbin-1-Ribozinoindole-1 99% | 10mg | $137.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon2663 | Rbin-1-Ribozinoindole-1 99% | 50mg | $522.5 | 2021-12-16 | Buy |
| Cayman Chemical | 20745 | Rbin-1 ≥98% | 1mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 20745 | Rbin-1 ≥98% | 5mg | $388 | 2024-03-01 | Buy |
| ChemScene | CS-6068 | Rbin-1 99.91% | 1mg | $110 | 2021-12-16 | Buy |
| ChemScene | CS-6068 | Rbin-1 99.91% | 5mg | $330 | 2021-12-16 | Buy |
| ChemScene | CS-6068 | Rbin-1 99.91% | 10mg | $500 | 2021-12-16 | Buy |
| ChemScene | CS-6068 | Rbin-1 99.91% | 25mg | $1000 | 2021-12-16 | Buy |
| ChemScene | CS-6068 | Rbin-1 99.91% | 50mg | $1500 | 2021-12-16 | Buy |
| ChemScene | CS-6068 | Rbin-1 99.91% | 100mg | $2100 | 2021-12-16 | Buy |
| Crysdot | CD11144576 | Rbin-1 97% | 5mg | $339 | 2021-12-16 | Buy |
| Crysdot | CD11144576 | Rbin-1 97% | 10mg | $513 | 2021-12-16 | Buy |
| Crysdot | CD11144576 | Rbin-1 97% | 25mg | $1026 | 2021-12-16 | Buy |
| Crysdot | CD11144576 | Rbin-1 97% | 50mg | $1538 | 2021-12-16 | Buy |
| DC Chemicals | DC11468 | Rbin-1 >98% | 100mg | $650 | 2021-12-16 | Buy |
Properties
Boiling point :479.6±47.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :10.34±0.50(Predicted)
form :solid
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :10.34±0.50(Predicted)
form :solid
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Rbin-1 is a triazinoindole inhibitor of midasin (mdn1), an essential protein for eukaryotic ribosome biogenesis. It inhibits the growth of fission yeast strains in vitro (GI50 = 136 nM) and inhibits mdn1 ATPase activity by approximately 40% when used at a concentration of 1 μM. Rbin-1 inhibits pre-rRNA processing and nuclear export of the pre-60S ribosome subunit in mdn1-ts, but not mdn1-F1093L mutant, S. pombe cells. It also decreases ribosome assembly protein 4 (Rsa4) levels in Rix1 particles, a ribosome assembly intermediate, Rix1-bound Ytm1 levels, and Rix7 and Ppp1 levels in the nucleolar pre-60S particle Nsa1 in mdn1-ts fission yeast cells.Related product price
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