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ChemicalBook >> CAS DataBase List >> SGC707

SGC707

SGC707 price.
  • $32 - $1800
  • Product name: SGC707
  • CAS: 1687736-54-4
  • MF: C16H18N4O2
  • MW: 298.34
  • EINECS:
  • MDL Number:MFCD28411624
  • Synonyms:SGC707;N-6-Isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea;SGC 707;SGC707;CS-2192;Urea, N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-
21 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4586EB
  • Product description1-Isoquinolin-6-Yl-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea
  • Packaging100mg
  • Price$1064
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6048
  • Product descriptionSGC707
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2945
  • Product descriptionSGC707 99%
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545936
  • Product descriptionSGC-707 >98%
  • Packaging5mg
  • Price$181.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545936
  • Product descriptionSGC-707 >98%
  • Packaging25mg
  • Price$489.6
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17017
  • Product descriptionSGC707 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17017
  • Product descriptionSGC707 ≥98%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17017
  • Product descriptionSGC707 ≥98%
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17017
  • Product descriptionSGC707 ≥98%
  • Packaging50mg
  • Price$669
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM250198
  • Product description1-(Isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98%
  • Packaging100mg
  • Price$539
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5370
  • Product descriptionSGC707 99.31%
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5370
  • Product descriptionSGC707 99.31%
  • Packaging50mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5370
  • Product descriptionSGC707 99.31%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5370
  • Product descriptionSGC707 99.31%
  • Packaging500mg
  • Price$1750
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003034
  • Product descriptionSGC707 98+%
  • Packaging50mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003034
  • Product descriptionSGC707 98+%
  • Packaging100mg
  • Price$681
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4586EB 1-Isoquinolin-6-Yl-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea 100mg $1064 2021-12-16 Buy
ApexBio Technology B6048 SGC707 10mg $75 2021-12-16 Buy
Axon Medchem Axon2945 SGC707 99% 10mg $99 2021-12-16 Buy
Biorbyt Ltd orb545936 SGC-707 >98% 5mg $181.9 2021-12-16 Buy
Biorbyt Ltd orb545936 SGC-707 >98% 25mg $489.6 2021-12-16 Buy
Cayman Chemical 17017 SGC707 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 17017 SGC707 ≥98% 10mg $169 2024-03-01 Buy
Cayman Chemical 17017 SGC707 ≥98% 25mg $381 2024-03-01 Buy
Cayman Chemical 17017 SGC707 ≥98% 50mg $669 2024-03-01 Buy
Chemenu CM250198 1-(Isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98% 100mg $539 2021-12-16 Buy
ChemScene CS-5370 SGC707 99.31% 10mg $65 2021-12-16 Buy
ChemScene CS-5370 SGC707 99.31% 50mg $225 2021-12-16 Buy
ChemScene CS-5370 SGC707 99.31% 100mg $450 2021-12-16 Buy
ChemScene CS-5370 SGC707 99.31% 500mg $1750 2021-12-16 Buy
Crysdot CD31003034 SGC707 98+% 50mg $375 2021-12-16 Buy
Crysdot CD31003034 SGC707 98+% 100mg $681 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Protein arginine N-methyltransferase 3 (PRMT3, ) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the Structural Genomics Consortium (SGC), SGC707 avidly binds PRMT3 (Kd = 50 nM by isothermal titration calorimetry) and inhibits the methylation of histones in cells with an IC50 value below 1 μM.

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