Ro 67-4853
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- $36 - $2590
- Product name: Ro 67-4853
- CAS: 302841-89-0
- MF: C19H19NO4
- MW: 325.36
- EINECS:
- MDL Number:MFCD20270618
- Synonyms:Ro 67-4853;(9H-Xanthen-9-ylcarbonyl)carbaMic Acid Butyl Ester;N-(9H-Xanthen-9-ylcarbonyl)carbaMic Acid Butyl Ester;Butyl 9H-xanthene-9-carbonylcarbamate;Carbamic acid, N-(9H-xanthen-9-ylcarbonyl)-, butyl ester;Ro 674853,Ro 67 4853;Ro 67-4853, Positive allosteric modulator of mGlu1
36 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 10
- 1mg
- 10mg
- 25MG
- 50mg
- 100.00mg
- 200mg
- 50
- 100MG
- 250MG
- 250.00mg
- Manufactureraablocks
- Product numberAA002ZDW
- Product descriptionRo 67-4853 ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002ZDW
- Product descriptionRo 67-4853 ≥98%
- Packaging10mg
- Price$103
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD279858
- Product descriptionRo 67-4853 98%
- Packaging5MG
- Price$170
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD279858
- Product descriptionRo 67-4853 98%
- Packaging25MG
- Price$425
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD279858
- Product descriptionRo 67-4853 98%
- Packaging100MG
- Price$895
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4451CR
- Product descriptionButyl9H-xanthene-9-carbonylcarbamate
- Packaging5mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010310
- Product description(9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00%
- Packaging250MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010310
- Product description(9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00%
- Packaging25MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7653
- Product descriptionRo 67-4853
- Packaging50mg
- Price$921
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7653
- Product descriptionRo 67-4853
- Packaging10mg
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7653
- Product descriptionRo 67-4853
- Packaging1mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7653
- Product descriptionRo 67-4853
- Packaging5mg
- Price$85
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1704149
- Product descriptionRo 67-4853 98.57%(Mayvarybetweenbatches)
- Packaging1mg
- Price$100
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1704149
- Product descriptionRo 67-4853 98.57%(Mayvarybetweenbatches)
- Packaging5mg
- Price$190
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1704149
- Product descriptionRo 67-4853 98.57%(Mayvarybetweenbatches)
- Packaging200mg
- Price$1030
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1704149
- Product descriptionRo 67-4853 98.57%(Mayvarybetweenbatches)
- Packaging100mg
- Price$790
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002ZDW | Ro 67-4853 ≥98% | 1mg | $36 | 2026-05-28 | Buy |
| aablocks | AA002ZDW | Ro 67-4853 ≥98% | 10mg | $103 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD279858 | Ro 67-4853 98% | 5MG | $170 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD279858 | Ro 67-4853 98% | 25MG | $425 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD279858 | Ro 67-4853 98% | 100MG | $895 | 2026-05-27 | Buy |
| AK Scientific | 4451CR | Butyl9H-xanthene-9-carbonylcarbamate | 5mg | $164 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010310 | (9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00% | 250MG | $1963.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010310 | (9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00% | 25MG | $750.75 | 2021-12-16 | Buy |
| ApexBio Technology | B7653 | Ro 67-4853 | 50mg | $921 | 2026-05-06 | Buy |
| ApexBio Technology | B7653 | Ro 67-4853 | 10mg | $130 | 2026-05-06 | Buy |
| ApexBio Technology | B7653 | Ro 67-4853 | 1mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | B7653 | Ro 67-4853 | 5mg | $85 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1704149 | Ro 67-4853 98.57%(Mayvarybetweenbatches) | 1mg | $100 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1704149 | Ro 67-4853 98.57%(Mayvarybetweenbatches) | 5mg | $190 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1704149 | Ro 67-4853 98.57%(Mayvarybetweenbatches) | 200mg | $1030 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1704149 | Ro 67-4853 98.57%(Mayvarybetweenbatches) | 100mg | $790 | 2026-05-06 | Buy |
Properties
Melting point :190-194°C
storage temp. :Refrigerator
solubility :Chloroform, Methanol
form :Solid
color :White
storage temp. :Refrigerator
solubility :Chloroform, Methanol
form :Solid
color :White
Safety Information
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Description
Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8, as well as at several other neural receptors. Ro 67-4853 can also directly activate mGluR1 signaling in baby hamster kidney cells, leading to phosphorylation of ERK1/2 (EC50 = 6.2 nM) and activation of adenylate cyclase (EC50 = 11.7 μM). Ro 67-4853 can also be used to enhance neuronal stimulation in response to the mGluR1/mGluR5 agonist DHPG, both in vivo and in vitro (EC50 = 95 nM).More related product prices
Ro 67-4853 Ro 67-7476 5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine Ro 01-6128Related product price
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Ro 67-4853
$36-2590 -
Ro 67-7476
$36-1958 -
5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine
$30-2691.1
Suppliers and manufacturers
J & K SCIENTIFIC LTD.
Chemsky（shanghai）International Co.,Ltd.
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
ShangHai ChuanQian Chemcial Technique Centre
Energy Chemical
MedBioPharmaceutical Technology Inc
Bide Pharmatech Ltd.
TargetMol Chemicals Inc.
