SR 1078
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- $32 - $1193
- Product name: SR 1078
- CAS: 1246525-60-9
- MF: C17H10F9NO2
- MW: 431.25
- EINECS:
- MDL Number:MFCD18782737
- Synonyms:N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide;SR 1078;SR1078,N-[4-(2,2,2-Trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-4-trifluoroMethyl-benzaMide;N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide SR1078;SR1078;SR 1078;SR-1078;N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxy-2-propanyl)phenyl]-4-(trifluoromethyl)benzamide;SR1078,N-[4-(2,2,2-TRIFLUORO-1-HYDROXY-1-TRIFLUOROMETHYL-ETHYL)-PHENYL]-4-TRIFLU;SR 1078; SR-1078
41 prices
Selected condition:
Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 1mlx10mM(inDMSO)
- 1MG
- 50
- 2mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 10 mg
- ManufacturerAmbeed
- Product numberA244776
- Product descriptionSR-1078 98+%
- Packaging10mg
- Price$36
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA244776
- Product descriptionSR-1078 98+%
- Packaging250mg
- Price$152
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014154
- Product descriptionSR-1078 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014154
- Product descriptionSR-1078 95.00%
- Packaging5MG
- Price$505.37
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3835
- Product descriptionSR1078
- Packaging50mg
- Price$370
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3835
- Product descriptionSR1078
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3835
- Product descriptionSR1078
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3835
- Product descriptionSR1078
- Packaging10mg
- Price$98
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3835
- Product descriptionSR1078
- Packaging200mg
- Price$1100
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1222793
- Product descriptionSR 1078 >98%(HPLC)
- Packaging2mg
- Price$100
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1302726
- Product descriptionSR1078 99.58%
- Packaging1mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1302726
- Product descriptionSR1078 99.58%
- Packaging2mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1222793
- Product descriptionSR 1078 >98%(HPLC)
- Packaging5mg
- Price$140
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1302726
- Product descriptionSR1078 99.58%
- Packaging1mlx10mM(inDMSO)
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1302726
- Product descriptionSR1078 99.58%
- Packaging5mg
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1302726
- Product descriptionSR1078 99.58%
- Packaging50mg
- Price$430
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A244776 | SR-1078 98+% | 10mg | $36 | 2021-12-16 | Buy |
| Ambeed | A244776 | SR-1078 98+% | 250mg | $152 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0014154 | SR-1078 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0014154 | SR-1078 95.00% | 5MG | $505.37 | 2021-12-16 | Buy |
| ApexBio Technology | A3835 | SR1078 | 50mg | $370 | 2026-05-06 | Buy |
| ApexBio Technology | A3835 | SR1078 | 10mg | $150 | 2021-12-16 | Buy |
| ApexBio Technology | A3835 | SR1078 | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A3835 | SR1078 | 10mg | $98 | 2026-05-06 | Buy |
| ApexBio Technology | A3835 | SR1078 | 200mg | $1100 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1222793 | SR 1078 >98%(HPLC) | 2mg | $100 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1302726 | SR1078 99.58% | 1mg | $80 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1302726 | SR1078 99.58% | 2mg | $90 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1222793 | SR 1078 >98%(HPLC) | 5mg | $140 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1302726 | SR1078 99.58% | 1mlx10mM(inDMSO) | $130 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1302726 | SR1078 99.58% | 5mg | $130 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1302726 | SR1078 99.58% | 50mg | $430 | 2026-05-06 | Buy |
Properties
Melting point :169℃
Boiling point :362.9±42.0 °C(Predicted)
Density :1.527±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO, Methanol (Slightly)
form :Solid
pka :9.21±0.15(Predicted)
color :Off-White
InChI :1S/C17H10F9NO2/c18-15(19,20)11-3-1-9(2-4-11)13(28)27-12-7-5-10(6-8-12)14(29,16(21,22)23)17(24,25)26/h1-8,29H,(H,27,28)
InChIKey :DUXWIYXHHGNUJU-UHFFFAOYSA-N
SMILES :O=C(NC1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1)C2=CC=C(C=C2)C(F)(F)F
Boiling point :362.9±42.0 °C(Predicted)
Density :1.527±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO, Methanol (Slightly)
form :Solid
pka :9.21±0.15(Predicted)
color :Off-White
InChI :1S/C17H10F9NO2/c18-15(19,20)11-3-1-9(2-4-11)13(28)27-12-7-5-10(6-8-12)14(29,16(21,22)23)17(24,25)26/h1-8,29H,(H,27,28)
InChIKey :DUXWIYXHHGNUJU-UHFFFAOYSA-N
SMILES :O=C(NC1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1)C2=CC=C(C=C2)C(F)(F)F
Safety Information
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Description
Retinoic acid receptor-related orphan receptors α and γ (RORα and RORγ) have been demonstrated to play important roles in the regulation of metabolism, circadian rhythms, immune function, and tumorigenesis. SR 1078 is a selective agonist of RORα and RORγ that stimulates ROR transcriptional activity in HEK293 cell reporter assays at concentrations as low as 2 μM without effect at the related liver X receptors and farnesoid X receptors. At 5 μM, SR 1078 has been shown to stabilize p53 and to induce apoptosis in HepG2 cancer cells.More related product prices
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