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ChemicalBook >> CAS DataBase List >> SR 0987

SR 0987

SR 0987 price.
  • $27 - $1000
  • Product name: SR 0987
  • CAS: 303126-97-8
  • MF: C16H10ClF6NO2
  • MW: 397.7
  • EINECS:
  • MDL Number:MFCD02693203
  • Synonyms:SR 0987;2-chloro-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)benzamide;2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide;SR 0987;SR-0987;SR0987;303126-97-8;Benzamide, 2-chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-;SR0987 >=98% (HPLC);SR0987,ROR,SR-0987,Inhibitor,SR 0987,inhibit,RAR-related orphan receptor
22 prices
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  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
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  • 5mg
  • 1mg
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  • 25mg
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  • ManufacturerAK Scientific
  • Product number7506CG
  • Product description2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide
  • Packaging10mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number7506CG
  • Product description2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide
  • Packaging25mg
  • Price$691
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4281
  • Product descriptionSR0987
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4281
  • Product descriptionSR0987
  • Packaging10mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19503
  • Product descriptionSR 0987 ≥98%
  • Packaging1mg
  • Price$27
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19503
  • Product descriptionSR 0987 ≥98%
  • Packaging5mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19503
  • Product descriptionSR 0987 ≥98%
  • Packaging10mg
  • Price$122
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19503
  • Product descriptionSR 0987 ≥98%
  • Packaging25mg
  • Price$236
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021368
  • Product descriptionSR0987 99.56%
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-0021368
  • Product descriptionSR0987 99.56%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021368
  • Product descriptionSR0987 99.56%
  • Packaging25mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021368
  • Product descriptionSR0987 99.56%
  • Packaging50mg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021368
  • Product descriptionSR0987 99.56%
  • Packaging100mg
  • Price$880
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD38000038
  • Product descriptionSR0987 98%
  • Packaging5mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD38000038
  • Product descriptionSR0987 98%
  • Packaging10mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD38000038
  • Product descriptionSR0987 98%
  • Packaging25mg
  • Price$280
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7506CG 2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide 10mg $370 2021-12-16 Buy
AK Scientific 7506CG 2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide 25mg $691 2021-12-16 Buy
ApexBio Technology C4281 SR0987 5mg $120 2021-12-16 Buy
ApexBio Technology C4281 SR0987 10mg $210 2021-12-16 Buy
Cayman Chemical 19503 SR 0987 ≥98% 1mg $27 2024-03-01 Buy
Cayman Chemical 19503 SR 0987 ≥98% 5mg $68 2024-03-01 Buy
Cayman Chemical 19503 SR 0987 ≥98% 10mg $122 2024-03-01 Buy
Cayman Chemical 19503 SR 0987 ≥98% 25mg $236 2024-03-01 Buy
ChemScene CS-0021368 SR0987 99.56% 5mg $80 2021-12-16 Buy
ChemScene CS-0021368 SR0987 99.56% 10mg $140 2021-12-16 Buy
ChemScene CS-0021368 SR0987 99.56% 25mg $290 2021-12-16 Buy
ChemScene CS-0021368 SR0987 99.56% 50mg $490 2021-12-16 Buy
ChemScene CS-0021368 SR0987 99.56% 100mg $880 2021-12-16 Buy
Crysdot CD38000038 SR0987 98% 5mg $64 2021-12-16 Buy
Crysdot CD38000038 SR0987 98% 10mg $113 2021-12-16 Buy
Crysdot CD38000038 SR0987 98% 25mg $280 2021-12-16 Buy

Properties

Boiling point :378.8±42.0 °C(Predicted)
Density :1.525±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) and Ethanol (up to at least 25 mg/ml)
pka :9.22±0.15(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SR 0987 is an agonist of the T cell-specific isoform of RORγ (RORγt, retinoic acid receptor-related orphan receptor-γt), inducing reporter gene expression with an EC50 value of ~800 nM. Stimulation of mouse EL4 T lymphocytes with SR 0987, following activation with PMA and ionomycin , increases expression of the RORγt target IL-17, while expression of the programmed cell death protein PD-1 is decreased and granzyme B is unchanged. Decreased cell surface PD-1 protein, assessed by flow cytometry, is observed in a variety of T cells treated with SR 0987.