SU 5416
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- $9 - $972
- Product name: SU 5416
- CAS: 204005-46-9
- MF: C15H14N2O
- MW: 238.28
- EINECS:200-256-5
- MDL Number:MFCD01940922
- Synonyms:H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-;SU 5416 (SeMaxinib);SU5416 /SU-5416;(Z)-3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one;3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one;3-[(3,5-diMethyl-1H-pyrrol-2-yl)Methylidene]-1H-indol-2-one;SEMAXINIB(SU 5416);3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
62 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 25mg
- 10mM(in 1mL DMSO)
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 50.00mg
- 50mg
- 100mg
- 100.00mg
- 250.00mg
- 250mg
- 0.25G
- 500MG
- 1G
- Manufactureraablocks
- Product numberAA002964
- Product description3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98%
- Packaging1mg
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002964
- Product description3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98%
- Packaging5mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002964
- Product description3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one ≥98%(HPLC)
- Packaging10mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002964
- Product description3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98%
- Packaging50mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002964
- Product description3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98%
- Packaging100mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002964
- Product description3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98%
- Packaging250mg
- Price$143
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16021
- Product descriptionSU5416 98%
- Packaging500MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16021
- Product descriptionSU5416 98%
- Packaging1G
- Price$245
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2033AH
- Product descriptionSemaxanib
- Packaging5mg
- Price$91
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA325242
- Product descriptionSU 5416 98+%
- Packaging100mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA325242
- Product descriptionSU 5416 98+%
- Packaging5mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA325242
- Product descriptionSU 5416 98+%
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA325242
- Product descriptionSU 5416 98+%
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA325242
- Product descriptionSU 5416 98+%
- Packaging1g
- Price$421
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA325242
- Product descriptionSU 5416 98+%
- Packaging250mg
- Price$421
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000244
- Product descriptionSU 5416 95.00%
- Packaging500MG
- Price$578
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002964 | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98% | 1mg | $9 | 2026-05-28 | Buy |
| aablocks | AA002964 | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98% | 5mg | $16 | 2026-05-28 | Buy |
| aablocks | AA002964 | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one ≥98%(HPLC) | 10mg | $18 | 2026-05-28 | Buy |
| aablocks | AA002964 | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98% | 50mg | $52 | 2026-05-28 | Buy |
| aablocks | AA002964 | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98% | 100mg | $82 | 2026-05-28 | Buy |
| aablocks | AA002964 | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one 98% | 250mg | $143 | 2026-05-28 | Buy |
| ACHEMBLOCK | R16021 | SU5416 98% | 500MG | $145 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16021 | SU5416 98% | 1G | $245 | 2026-05-27 | Buy |
| AK Scientific | 2033AH | Semaxanib | 5mg | $91 | 2021-12-16 | Buy |
| Ambeed | A325242 | SU 5416 98+% | 100mg | $169 | 2021-12-16 | Buy |
| Ambeed | A325242 | SU 5416 98+% | 5mg | $30 | 2021-12-16 | Buy |
| Ambeed | A325242 | SU 5416 98+% | 10mg | $50 | 2021-12-16 | Buy |
| Ambeed | A325242 | SU 5416 98+% | 50mg | $50 | 2021-12-16 | Buy |
| Ambeed | A325242 | SU 5416 98+% | 1g | $421 | 2021-12-16 | Buy |
| Ambeed | A325242 | SU 5416 98+% | 250mg | $421 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000244 | SU 5416 95.00% | 500MG | $578 | 2021-12-16 | Buy |
Properties
Melting point :226-228 °C
Boiling point :481.4±45.0 °C(Predicted)
Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: insoluble
pka :12.59±0.20(Predicted)
form :Yellow orange solid
color :yellow to yellow orange
InChI :InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)
InChIKey :WUWDLXZGHZSWQZ-UHFFFAOYSA-N
SMILES :N1C2=C(C=CC=C2)C(=CC2=C(C)C=C(C)N2)C1=O
Boiling point :481.4±45.0 °C(Predicted)
Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: insoluble
pka :12.59±0.20(Predicted)
form :Yellow orange solid
color :yellow to yellow orange
InChI :InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)
InChIKey :WUWDLXZGHZSWQZ-UHFFFAOYSA-N
SMILES :N1C2=C(C=CC=C2)C(=CC2=C(C)C=C(C)N2)C1=O
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
SU 5416 is a tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR2; FLK1/KDR) and a suppressor of tumor vascularization, preventing the growth of multiple tumor types. In addition to inhibiting VEGFR2 (IC50 = 1 μM), SU 5416 also inhibits PDGFR (IC50 = 20 μM), c-Kit (IC50 = 30 nM), RET (IC50 = 170 nM), FLT3 (IC50 = 160 nM), ABL (IC50 = 11 μM), and ALK (IC50 = 1.2 μM). SU 5416 does not inhibit epidermal growth factor or fibroblast growth factor receptor tyrosine kinases (IC50 > 100 μM).More related product prices
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