Safinamide
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- $10 - $1949.9
- Product name: Safinamide
- CAS: 133865-89-1
- MF: C17H19FN2O2
- MW: 302.34
- EINECS:603-772-2
- MDL Number:MFCD00897036
- Synonyms:SAFINAMIDE:(S)-(+)-2-[4-(3-FLUOROBENZYLOXY)BENZYLAMINO]PROPANAMIDE METHANSULFONATE;FCE 26743;Safinamide;2(S)-[4-(3-Fluorobenzyloxy)benzylamino]propionamide;PropanaMide,2-[[[4-[(3-fluorophenyl)Methoxy]phenyl]Methyl]aMino]-, (2S)-;(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)aMino)propanaMide;(S)-(+)-2-[4-(3-FLUOROBENZYLOXY)BENZYLAMINO]PROPANAMIDE METHANSULFONATE;EMD 1195686
67 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- TCI Chemical
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 250mg
- 250.00mg
- 500mg
- 1g
- 5g
- 10g
- 25G
- Manufactureraablocks
- Product numberAA0038VE
- Product description(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide 98%
- Packaging1g
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038VE
- Product description(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide 98%
- Packaging5g
- Price$103
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038VE
- Product description(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide ≥98%
- Packaging250mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038VE
- Product description(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide ≥98%
- Packaging50mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0038VE
- Product description(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide ≥98%
- Packaging10mg
- Price$10
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228856
- Product descriptionSafinamide 97.00%
- Packaging5G
- Price$120
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228856
- Product descriptionSafinamide 97.00%
- Packaging25G
- Price$460
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number6135AA
- Product description(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide
- Packaging100mg
- Price$614
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6135AA
- Product description(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide
- Packaging25mg
- Price$254
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA189271
- Product descriptionSafinamide 98+%
- Packaging100mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA189271
- Product descriptionSafinamide 98+%
- Packaging250mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA189271
- Product descriptionSafinamide 98+%
- Packaging1g
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3784
- Product descriptionSafinamide
- Packaging10mg
- Price$51
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3784
- Product descriptionSafinamide
- Packaging10mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3784
- Product descriptionSafinamide
- Packaging50mg
- Price$122
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3784
- Product descriptionSafinamide
- Packaging500mg
- Price$706
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0038VE | (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide 98% | 1g | $31 | 2026-05-28 | Buy |
| aablocks | AA0038VE | (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide 98% | 5g | $103 | 2026-05-28 | Buy |
| aablocks | AA0038VE | (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide ≥98% | 250mg | $14 | 2026-05-28 | Buy |
| aablocks | AA0038VE | (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide ≥98% | 50mg | $11 | 2026-05-28 | Buy |
| aablocks | AA0038VE | (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide ≥98% | 10mg | $10 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y228856 | Safinamide 97.00% | 5G | $120 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228856 | Safinamide 97.00% | 25G | $460 | 2026-05-27 | Buy |
| AK Scientific | 6135AA | (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide | 100mg | $614 | 2021-12-16 | Buy |
| AK Scientific | 6135AA | (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide | 25mg | $254 | 2021-12-16 | Buy |
| Ambeed | A189271 | Safinamide 98+% | 100mg | $15 | 2021-12-16 | Buy |
| Ambeed | A189271 | Safinamide 98+% | 250mg | $24 | 2021-12-16 | Buy |
| Ambeed | A189271 | Safinamide 98+% | 1g | $58 | 2021-12-16 | Buy |
| ApexBio Technology | A3784 | Safinamide | 10mg | $51 | 2026-05-06 | Buy |
| ApexBio Technology | A3784 | Safinamide | 10mg | $96 | 2021-12-16 | Buy |
| ApexBio Technology | A3784 | Safinamide | 50mg | $122 | 2026-05-06 | Buy |
| ApexBio Technology | A3784 | Safinamide | 500mg | $706 | 2026-05-06 | Buy |
Properties
Melting point :208-212°
Boiling point :476.7±40.0 °C(Predicted)
Density :1.189±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :16.03±0.50(Predicted)
color :White
Merck :14,8315
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C17H19FN2O2/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14/h2-9,12,20H,10-11H2,1H3,(H2,19,21)/t12-/m0/s1
InChIKey :NEMGRZFTLSKBAP-LBPRGKRZSA-N
SMILES :C(N)(=O)[C@@H](NCC1=CC=C(OCC2=CC=CC(F)=C2)C=C1)C
Boiling point :476.7±40.0 °C(Predicted)
Density :1.189±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :16.03±0.50(Predicted)
color :White
Merck :14,8315
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C17H19FN2O2/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14/h2-9,12,20H,10-11H2,1H3,(H2,19,21)/t12-/m0/s1
InChIKey :NEMGRZFTLSKBAP-LBPRGKRZSA-N
SMILES :C(N)(=O)[C@@H](NCC1=CC=C(OCC2=CC=CC(F)=C2)C=C1)C
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Safinamide (133865-89-1) is a selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1Displays anticonvulsant activity2and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4A novel therapeutic for Parkinson’s disease with multiple modes of action.5Effective as an add-on to dopamine agonist therapy in early Parkinson’s.6Related product price
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