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ChemicalBook >> CAS DataBase List >> Safinamide

Safinamide

Safinamide price.
  • $15 - $1949.9
  • Product name: Safinamide
  • CAS: 133865-89-1
  • MF: C17H19FN2O2
  • MW: 302.34
  • EINECS:603-772-2
  • MDL Number:MFCD00897036
  • Synonyms:SAFINAMIDE:(S)-(+)-2-[4-(3-FLUOROBENZYLOXY)BENZYLAMINO]PROPANAMIDE METHANSULFONATE;FCE 26743;Safinamide;2(S)-[4-(3-Fluorobenzyloxy)benzylamino]propionamide;PropanaMide,2-[[[4-[(3-fluorophenyl)Methoxy]phenyl]Methyl]aMino]-, (2S)-;(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)aMino)propanaMide;(S)-(+)-2-[4-(3-FLUOROBENZYLOXY)BENZYLAMINO]PROPANAMIDE METHANSULFONATE;EMD 1195686
27 prices
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Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • TCI Chemical
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 10g
  • ManufacturerAK Scientific
  • Product number6135AA
  • Product description(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide
  • Packaging25mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6135AA
  • Product description(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide
  • Packaging100mg
  • Price$614
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA189271
  • Product descriptionSafinamide 98+%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA189271
  • Product descriptionSafinamide 98+%
  • Packaging250mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA189271
  • Product descriptionSafinamide 98+%
  • Packaging1g
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3784
  • Product descriptionSafinamide
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3784
  • Product descriptionSafinamide
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3784
  • Product descriptionSafinamide
  • Packaging500mg
  • Price$924
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS469731
  • Product descriptionSafinamide ≥98%
  • Packaging5mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS469731
  • Product descriptionSafinamide ≥98%
  • Packaging10mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS469731
  • Product descriptionSafinamide ≥98%
  • Packaging25mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS469731
  • Product descriptionSafinamide ≥98%
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146172
  • Product descriptionSafinamide >99%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146172
  • Product descriptionSafinamide >99%
  • Packaging250mg
  • Price$1060.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146172
  • Product descriptionSafinamide >99%
  • Packaging1g
  • Price$1949.9
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number38260
  • Product descriptionSafinamide,98%(HPLC) 98%(HPLC)
  • Packaging25MG
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6135AA (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide 25mg $254 2021-12-16 Buy
AK Scientific 6135AA (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide 100mg $614 2021-12-16 Buy
Ambeed A189271 Safinamide 98+% 100mg $15 2021-12-16 Buy
Ambeed A189271 Safinamide 98+% 250mg $24 2021-12-16 Buy
Ambeed A189271 Safinamide 98+% 1g $58 2021-12-16 Buy
ApexBio Technology A3784 Safinamide 10mg $96 2021-12-16 Buy
ApexBio Technology A3784 Safinamide 50mg $300 2021-12-16 Buy
ApexBio Technology A3784 Safinamide 500mg $924 2021-12-16 Buy
Arctom AS469731 Safinamide ≥98% 5mg $46 2021-12-16 Buy
Arctom AS469731 Safinamide ≥98% 10mg $86 2021-12-16 Buy
Arctom AS469731 Safinamide ≥98% 25mg $158 2021-12-16 Buy
Arctom AS469731 Safinamide ≥98% 50mg $290 2021-12-16 Buy
Biorbyt Ltd orb146172 Safinamide >99% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb146172 Safinamide >99% 250mg $1060.8 2021-12-16 Buy
Biorbyt Ltd orb146172 Safinamide >99% 1g $1949.9 2021-12-16 Buy
Chem-Impex 38260 Safinamide,98%(HPLC) 98%(HPLC) 25MG $140 2021-12-16 Buy

Properties

Melting point :208-212°
Boiling point :476.7±40.0 °C(Predicted)
Density :1.189±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :16.03±0.50(Predicted)
color :White
Merck :14,8315
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Safinamide (133865-89-1) is a selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1?Displays anticonvulsant activity2?and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4?A novel therapeutic for Parkinson’s disease with multiple modes of action.5?Effective as an add-on to dopamine agonist therapy in early Parkinson’s.6

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