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ChemicalBook >> CAS DataBase List >> Suvorexant

Suvorexant

Suvorexant price.
  • $39 - $2904
  • Product name: Suvorexant
  • CAS: 1030377-33-3
  • MF: C23H23ClN6O2
  • MW: 450.92
  • EINECS:685-109-7
  • MDL Number:MFCD22377755
  • Synonyms:5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl]-1,3-benzoxazole;Suvorexant;MK-4305 (Suvorexant);Methanone, [(7R)-4-(5-chloro-2-benzoxazolyl)hexahydro-7-Methyl-1H-1,4-diazepin-1-yl][5-Methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]-;Suvorexant (MK-4305);Suvorexant (with 4 ints.);SUVOREXABT;Synonyms Suvorexant
26 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 1mg
  • 10mg
  • 5MG
  • 10mM*1mLinDMSO
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • 50 mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006854
  • Product descriptionMK-4305 95.00%
  • Packaging5MG
  • Price$503.61
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146219
  • Product descriptionSuvorexant
  • Packaging250mg
  • Price$760
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146219
  • Product descriptionSuvorexant
  • Packaging100mg
  • Price$390
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146219
  • Product descriptionSuvorexant
  • Packaging1g
  • Price$1260
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberFS65089
  • Product descriptionSuvorexant
  • Packaging100mg
  • Price$1210
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFS65089
  • Product descriptionSuvorexant
  • Packaging250mg
  • Price$2270
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFS65089
  • Product descriptionSuvorexant
  • Packaging25mg
  • Price$453.75
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFS65089
  • Product descriptionSuvorexant
  • Packaging10mg
  • Price$242
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFS65089
  • Product descriptionSuvorexant
  • Packaging50mg
  • Price$756.5
  • Updated2026-06-04
  • Buy
  • ManufacturerCayman Chemical
  • Product number22911
  • Product descriptionSuvorexant ≥98%
  • Packaging50mg
  • Price$758
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002140
  • Product descriptionSuvorexant ≥98%
  • Packaging50mg
  • Price$530
  • Updated2022-04-27
  • Buy
  • ManufacturerCayman Chemical
  • Product number22911
  • Product descriptionSuvorexant ≥98%
  • Packaging50 mg
  • Price$689
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22911
  • Product descriptionSuvorexant ≥98%
  • Packaging1mg
  • Price$62
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number22911
  • Product descriptionSuvorexant ≥98%
  • Packaging5mg
  • Price$137
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002140
  • Product descriptionSuvorexant ≥98%
  • Packaging10mg
  • Price$152
  • Updated2022-04-27
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002140
  • Product descriptionSuvorexant ≥98%
  • Packaging5mg
  • Price$86
  • Updated2022-04-27
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0006854 MK-4305 95.00% 5MG $503.61 2021-12-16 Buy
Biorbyt Ltd orb146219 Suvorexant 250mg $760 2026-05-06 Buy
Biorbyt Ltd orb146219 Suvorexant 100mg $390 2026-05-06 Buy
Biorbyt Ltd orb146219 Suvorexant 1g $1260 2026-05-06 Buy
Biosynth FS65089 Suvorexant 100mg $1210 2026-06-04 Buy
Biosynth FS65089 Suvorexant 250mg $2270 2026-06-04 Buy
Biosynth FS65089 Suvorexant 25mg $453.75 2026-06-04 Buy
Biosynth FS65089 Suvorexant 10mg $242 2026-06-04 Buy
Biosynth FS65089 Suvorexant 50mg $756.5 2026-06-04 Buy
Cayman Chemical 22911 Suvorexant ≥98% 50mg $758 2026-04-30 Buy
Cayman Chemical 9002140 Suvorexant ≥98% 50mg $530 2022-04-27 Buy
Cayman Chemical 22911 Suvorexant ≥98% 50 mg $689 2024-03-01 Buy
Cayman Chemical 22911 Suvorexant ≥98% 1mg $62 2026-04-30 Buy
Cayman Chemical 22911 Suvorexant ≥98% 5mg $137 2026-04-30 Buy
Cayman Chemical 9002140 Suvorexant ≥98% 10mg $152 2022-04-27 Buy
Cayman Chemical 9002140 Suvorexant ≥98% 5mg $86 2022-04-27 Buy

Properties

Melting point :153℃
Boiling point :669.8±65.0 °C(Predicted)
Density :1.41
storage temp. :Room Temperature
solubility :Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly, Heated)
form :Solid
pka :1.47±0.40(Predicted)
color :White to Pale Beige
InChIKey :JYTNQNCOQXFQPK-MRXNPFEDSA-N
SMILES :C(N1[C@H](C)CCN(C2=NC3=CC(Cl)=CC=C3O2)CC1)(C1=CC(C)=CC=C1N1N=CC=N1)=O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Suvorexant (Belsomra® ) is a novel sedative hypnotic drug that is prescribed to promote sleep in patients with insomnia. It is the first of a new class of drugs classified as dual orexin receptor antagonists (DORAs) and is currently approved for the treatment of insomnia in the United States and Japan. It is a CNS depressant and blocks the binding of wake-promoting neuropeptides orexin A and orexin B to the two orexin receptors (OX1R and OX2R) thus, altering the signaling (action) of orexin in the brain and suppressing the sleep-wake drive.

Suvorexant is a central nervous system (CNS) depressant and can impair daytime wakefulness even when used as prescribed. Prescribers should monitor for somnolence and CNS depressant effects, but impairment can occur in the absence of symptoms, and may not be reliably detected by ordinary clinical exam. CNS depressant effects may persist in some patients for up to several days after discontinuing Suvorexant.

Belsomra (Suvorexant) can impair driving skills and may increase the risk of falling asleep while driving. Discontinue or decrease the dose in patients who drive if daytime somnolence develops. Caution patients taking Belsomra 20 mg against next-day driving and other activities requiring full mental alertness. Caution patients taking lower doses of Belsomra as well, because there is individual variation in sensitivity to Belsomra.

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