Suvorexant
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- $39 - $2904
- Product name: Suvorexant
- CAS: 1030377-33-3
- MF: C23H23ClN6O2
- MW: 450.92
- EINECS:685-109-7
- MDL Number:MFCD22377755
- Synonyms:5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl]-1,3-benzoxazole;Suvorexant;MK-4305 (Suvorexant);Methanone, [(7R)-4-(5-chloro-2-benzoxazolyl)hexahydro-7-Methyl-1H-1,4-diazepin-1-yl][5-Methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]-;Suvorexant (MK-4305);Suvorexant (with 4 ints.);SUVOREXABT;Synonyms Suvorexant
26 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- DC Chemicals
- TRC
- Usbiological
Package
- 1mg
- 10mg
- 5MG
- 10mM*1mLinDMSO
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 50 mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0006854
- Product descriptionMK-4305 95.00%
- Packaging5MG
- Price$503.61
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146219
- Product descriptionSuvorexant
- Packaging250mg
- Price$760
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146219
- Product descriptionSuvorexant
- Packaging100mg
- Price$390
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146219
- Product descriptionSuvorexant
- Packaging1g
- Price$1260
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberFS65089
- Product descriptionSuvorexant
- Packaging100mg
- Price$1210
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFS65089
- Product descriptionSuvorexant
- Packaging250mg
- Price$2270
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFS65089
- Product descriptionSuvorexant
- Packaging25mg
- Price$453.75
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFS65089
- Product descriptionSuvorexant
- Packaging10mg
- Price$242
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFS65089
- Product descriptionSuvorexant
- Packaging50mg
- Price$756.5
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number22911
- Product descriptionSuvorexant ≥98%
- Packaging50mg
- Price$758
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number9002140
- Product descriptionSuvorexant ≥98%
- Packaging50mg
- Price$530
- Updated2022-04-27
- Buy
- ManufacturerCayman Chemical
- Product number22911
- Product descriptionSuvorexant ≥98%
- Packaging50 mg
- Price$689
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22911
- Product descriptionSuvorexant ≥98%
- Packaging1mg
- Price$62
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number22911
- Product descriptionSuvorexant ≥98%
- Packaging5mg
- Price$137
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number9002140
- Product descriptionSuvorexant ≥98%
- Packaging10mg
- Price$152
- Updated2022-04-27
- Buy
- ManufacturerCayman Chemical
- Product number9002140
- Product descriptionSuvorexant ≥98%
- Packaging5mg
- Price$86
- Updated2022-04-27
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0006854 | MK-4305 95.00% | 5MG | $503.61 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146219 | Suvorexant | 250mg | $760 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb146219 | Suvorexant | 100mg | $390 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb146219 | Suvorexant | 1g | $1260 | 2026-05-06 | Buy |
| Biosynth | FS65089 | Suvorexant | 100mg | $1210 | 2026-06-04 | Buy |
| Biosynth | FS65089 | Suvorexant | 250mg | $2270 | 2026-06-04 | Buy |
| Biosynth | FS65089 | Suvorexant | 25mg | $453.75 | 2026-06-04 | Buy |
| Biosynth | FS65089 | Suvorexant | 10mg | $242 | 2026-06-04 | Buy |
| Biosynth | FS65089 | Suvorexant | 50mg | $756.5 | 2026-06-04 | Buy |
| Cayman Chemical | 22911 | Suvorexant ≥98% | 50mg | $758 | 2026-04-30 | Buy |
| Cayman Chemical | 9002140 | Suvorexant ≥98% | 50mg | $530 | 2022-04-27 | Buy |
| Cayman Chemical | 22911 | Suvorexant ≥98% | 50 mg | $689 | 2024-03-01 | Buy |
| Cayman Chemical | 22911 | Suvorexant ≥98% | 1mg | $62 | 2026-04-30 | Buy |
| Cayman Chemical | 22911 | Suvorexant ≥98% | 5mg | $137 | 2026-04-30 | Buy |
| Cayman Chemical | 9002140 | Suvorexant ≥98% | 10mg | $152 | 2022-04-27 | Buy |
| Cayman Chemical | 9002140 | Suvorexant ≥98% | 5mg | $86 | 2022-04-27 | Buy |
Properties
Melting point :153℃
Boiling point :669.8±65.0 °C(Predicted)
Density :1.41
storage temp. :Room Temperature
solubility :Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly, Heated)
form :Solid
pka :1.47±0.40(Predicted)
color :White to Pale Beige
InChIKey :JYTNQNCOQXFQPK-MRXNPFEDSA-N
SMILES :C(N1[C@H](C)CCN(C2=NC3=CC(Cl)=CC=C3O2)CC1)(C1=CC(C)=CC=C1N1N=CC=N1)=O
Boiling point :669.8±65.0 °C(Predicted)
Density :1.41
storage temp. :Room Temperature
solubility :Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly, Heated)
form :Solid
pka :1.47±0.40(Predicted)
color :White to Pale Beige
InChIKey :JYTNQNCOQXFQPK-MRXNPFEDSA-N
SMILES :C(N1[C@H](C)CCN(C2=NC3=CC(Cl)=CC=C3O2)CC1)(C1=CC(C)=CC=C1N1N=CC=N1)=O
Safety Information
| Symbol(GHS): |
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Description
Suvorexant (Belsomra® ) is a novel sedative hypnotic drug that is prescribed to promote sleep in patients with insomnia. It is the first of a new class of drugs classified as dual orexin receptor antagonists (DORAs) and is currently approved for the treatment of insomnia in the United States and Japan. It is a CNS depressant and blocks the binding of wake-promoting neuropeptides orexin A and orexin B to the two orexin receptors (OX1R and OX2R) thus, altering the signaling (action) of orexin in the brain and suppressing the sleep-wake drive.Suvorexant is a central nervous system (CNS) depressant and can impair daytime wakefulness even when used as prescribed. Prescribers should monitor for somnolence and CNS depressant effects, but impairment can occur in the absence of symptoms, and may not be reliably detected by ordinary clinical exam. CNS depressant effects may persist in some patients for up to several days after discontinuing Suvorexant.
Belsomra (Suvorexant) can impair driving skills and may increase the risk of falling asleep while driving. Discontinue or decrease the dose in patients who drive if daytime somnolence develops. Caution patients taking Belsomra 20 mg against next-day driving and other activities requiring full mental alertness. Caution patients taking lower doses of Belsomra as well, because there is individual variation in sensitivity to Belsomra.
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