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ChemicalBook >> CAS DataBase List >> TAK-632

TAK-632

TAK-632 price.
  • $28 - $2691.1
  • Product name: TAK-632
  • CAS: 1228591-30-7
  • MF: C27H18F4N4O3S
  • MW: 554.52
  • EINECS:200-256-5
  • MDL Number:MFCD26960965
  • Synonyms:TAK-632;N-(7-CYANO-6-(4-FLUORO-3-(2-(3-(TRIFLUOROMETHYL)PHENYL)ACETAMIDO)PHENOXY)BENZO[D]THIAZOL-2-YL)CYCLOPROPANECARBOXAMIDE;N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide;TAK-0632;N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide TAK632;TAK 632 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide;TAK-632, >=98%;TAK2 63 (Free base)
Price83 Properties Safety Information Description
83 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • EvaluationSample
  • 1unit
  • 20mg
  • 10mM(in1mLDMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO
  • 250mg
  • 10mM*1mLinDMSO(Solution)
  • 1000mg
  • 1mg
  • 5mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 10mg
  • 50mg
  • 100mg
  • 200mg
  • 1G
  • Manufactureraablocks
  • Product numberAA000JJ9
  • Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
  • Packaging5mg
  • Price$48
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JJ9
  • Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide ≥98%
  • Packaging1mg
  • Price$36
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JJ9
  • Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 98%
  • Packaging10mg
  • Price$51
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JJ9
  • Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
  • Packaging25mg
  • Price$83
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JJ9
  • Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
  • Packaging50mg
  • Price$121
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JJ9
  • Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
  • Packaging100mg
  • Price$199
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JJ9
  • Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
  • Packaging200mg
  • Price$252
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging100MG
  • Price$295
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging100MG
  • Price$295
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging25MG
  • Price$120
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging25MG
  • Price$120
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging5MG
  • Price$45
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging5MG
  • Price$45
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging1G
  • Price$1250
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33834
  • Product descriptionTAK-632 98%
  • Packaging1G
  • Price$1250
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1203-M100
  • Product descriptionTAK-632 ≥95%
  • Packaging100mg
  • Price$1069
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000JJ9 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 5mg $48 2026-05-25 Buy
aablocks AA000JJ9 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide ≥98% 1mg $36 2026-05-25 Buy
aablocks AA000JJ9 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 98% 10mg $51 2026-05-25 Buy
aablocks AA000JJ9 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 25mg $83 2026-05-25 Buy
aablocks AA000JJ9 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 50mg $121 2026-05-25 Buy
aablocks AA000JJ9 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 100mg $199 2026-05-25 Buy
aablocks AA000JJ9 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 200mg $252 2026-05-25 Buy
ACHEMBLOCK O33834 TAK-632 98% 100MG $295 2026-05-25 Buy
ACHEMBLOCK O33834 TAK-632 98% 100MG $295 2026-05-27 Buy
ACHEMBLOCK O33834 TAK-632 98% 25MG $120 2026-05-25 Buy
ACHEMBLOCK O33834 TAK-632 98% 25MG $120 2026-05-27 Buy
ACHEMBLOCK O33834 TAK-632 98% 5MG $45 2026-05-25 Buy
ACHEMBLOCK O33834 TAK-632 98% 5MG $45 2026-05-27 Buy
ACHEMBLOCK O33834 TAK-632 98% 1G $1250 2026-05-25 Buy
ACHEMBLOCK O33834 TAK-632 98% 1G $1250 2026-05-27 Buy
Adipogen Life Sciences SYN-1203-M100 TAK-632 ≥95% 100mg $1069 2021-12-16 Buy
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Properties

Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥27.75 mg/mL in DMSO; insoluble in H2O; ≥2.23 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :9.59±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TAK-632 is a slow off-rate inhibitor of Raf kinases (IC50s = 8.3, 2.4, and 1.4 nM for wild type B-Raf, mutant B-RafV600E, and c-Raf, respectively). It demonstrates 14-1,200-fold selectivity for Raf over a panel of 26 different kinases. TAK-632 shows significant antiproliferative activity against mutated B-Raf or mutated N-Ras cancer cell lines and xenograft models, inhibiting MEK phosphorylation with an IC50 value of 12 nM and downstream ERK phosphorylation with an IC50 value of 16 nM.

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Suppliers and manufacturers

career henan chemical co
TAK-632
$5.00
TAK-632 CAS:1228591-30-7
TargetMol Chemicals Inc.
TAK-632
$35.00
TAK-632 CAS:1228591-30-7
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
Aladdin Scientific