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ChemicalBook >> CAS DataBase List >> TRIACSIN C

TRIACSIN C

TRIACSIN C price.
  • $173 - $7645
  • Product name: TRIACSIN C
  • CAS: 76896-80-5
  • MF: C11H17N3O
  • MW: 207.27
  • EINECS:616-408-2
  • MDL Number:MFCD00798237
  • Synonyms:TRIACSIN C;WS1228A;2,4,7-UNDECATRIENAL NITROSOHYDRAZONE;2E, 4E, 7E-UNDECATRIENE-1-TRIAZENE;Triacsincapprox.90%;2,4,7-Undecatrienal;triacsin c from streptomyces sp.;2E,4E,7E-undecatriene-1-triazine
10 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 100ug
  • 500μg
  • 500ug
  • 1mg
  • 2.5mg
  • 100U
  • ManufacturerAK Scientific
  • Product number9144AJ
  • Product descriptionTriacsinC
  • Packaging1mg
  • Price$653
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000138
  • Product descriptionTRIACSIN C 95.00%
  • Packaging1MG
  • Price$597.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7070
  • Product descriptionTriacsinC
  • Packaging500ug
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7070
  • Product descriptionTriacsinC
  • Packaging1mg
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007448
  • Product descriptionTriacsin C ≥95%
  • Packaging500μg
  • Price$287
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007448
  • Product descriptionTriacsin C ≥95%
  • Packaging1mg
  • Price$515
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberT4540
  • Product descriptionTriacsin C from Streptomyces sp.
  • Packaging1mg
  • Price$636
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2472
  • Product descriptionTriacsinC ≥95%(HPLC)
  • Packaging100U
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT767085
  • Product descriptionTriacsinC
  • Packaging2.5mg
  • Price$7645
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256968
  • Product descriptionTriacsin C
  • Packaging100ug
  • Price$432
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9144AJ TriacsinC 1mg $653 2021-12-16 Buy
American Custom Chemicals Corporation INB0000138 TRIACSIN C 95.00% 1MG $597.45 2021-12-16 Buy
ApexBio Technology B7070 TriacsinC 500ug $252 2021-12-16 Buy
ApexBio Technology B7070 TriacsinC 1mg $452 2021-12-16 Buy
Cayman Chemical 10007448 Triacsin C ≥95% 500μg $287 2024-03-01 Buy
Cayman Chemical 10007448 Triacsin C ≥95% 1mg $515 2024-03-01 Buy
Sigma-Aldrich T4540 Triacsin C from Streptomyces sp. 1mg $636 2024-03-01 Buy
Tocris 2472 TriacsinC ≥95%(HPLC) 100U $173 2021-12-16 Buy
TRC T767085 TriacsinC 2.5mg $7645 2021-12-16 Buy
Usbiological 256968 Triacsin C 100ug $432 2021-12-16 Buy

Properties

Boiling point :320.7±45.0 °C(Predicted)
Density :0.94±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :methanol: soluble4.90 - 5.10 mg/mL, clear (Pale yellow to yellow)
form :Liquid. In DMSO.
pka :-0.10±0.70(Predicted)
color :clear (Pale yellow to yellow) Solution in DMSO
Stability :Stable for 1 year from date of purchase as supplied. Solutions further diluted with DMSO may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Triacsin C was originally isolated from a Streptomyces aureofaciens culture. The compound is an inhibitor of long fatty acid acyl-CoA synthetase (ACSL) in intact cells and the nonspecific ACSL in cell sonicates (IC50=3.6-8.7 μM). Triacsin C has been shown to inhibit de novo synthesis of triacylglycerol, diacylglycerol, cholesterol esters, and phospholipids. The inhibitory effect of Triacsin C prevents degranulation by human neutrophils through superoxide anion generation inhibition, thus inhibiting neutrophil activity. Triacsin C has been classified as a hypotensive vasodilator which may act by increasing methacholine-induced NO synthesis. The compound has also been reported to inhibit β-cells by abolishing L-type Ca2+ CP (L-type Ca2+) channel modulation.

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