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ChemicalBook >> CAS DataBase List >> UK 1

UK 1

UK 1 price.
  • $80 - $1390
  • Product name: UK 1
  • CAS: 151271-53-3
  • MF: C22H14N2O5
  • MW: 386.36
  • EINECS:
  • MDL Number:
  • Synonyms:UK 1;UK 1 (cytotoxin);2'-(2-Hydroxyphenyl)-[2,4'-bibenzoxazole]-4-carboxylic acid methyl ester;[2,4'-Bibenzoxazole]-4-carboxylic acid, 2'-(2-hydroxyphenyl)-, methyl ester;UK-1, Topoisomerase II (Topo II) inhibitor
10 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 250ug
  • 250μg
  • 1mg
  • 5mg
  • ManufacturerAdipogen Life Sciences
  • Product numberBVT-0013-C250
  • Product descriptionAntibioticUK-1 ≥98%(HPLC)
  • Packaging250μg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9025CA
  • Product descriptionMethyl2'-(2-hydroxyphenyl)-(2,4'-bibenzoxazole)-4-carboxylate
  • Packaging5mg
  • Price$1390
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009863
  • Product description2-[2-(2-HYDROXYPHENYL)BENZOXAZOL-4-YL]BENZOXAZOLE-4-CARBOXYLIC ACID METHYL ESTER 95.00%
  • Packaging5MG
  • Price$496.71
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5006
  • Product descriptionUK1
  • Packaging1mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5006
  • Product descriptionUK1
  • Packaging5mg
  • Price$1325
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20139
  • Product descriptionUK 1 ≥95%
  • Packaging1mg
  • Price$279
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20139
  • Product descriptionUK 1 ≥95%
  • Packaging5mg
  • Price$1182
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberU700623
  • Product descriptionUK-1
  • Packaging250μg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number207430
  • Product descriptionUK-1
  • Packaging250ug
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberU0884-01
  • Product descriptionUK-1
  • Packaging1mg
  • Price$513
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences BVT-0013-C250 AntibioticUK-1 ≥98%(HPLC) 250μg $80 2021-12-16 Buy
AK Scientific 9025CA Methyl2'-(2-hydroxyphenyl)-(2,4'-bibenzoxazole)-4-carboxylate 5mg $1390 2021-12-16 Buy
American Custom Chemicals Corporation INB0009863 2-[2-(2-HYDROXYPHENYL)BENZOXAZOL-4-YL]BENZOXAZOLE-4-CARBOXYLIC ACID METHYL ESTER 95.00% 5MG $496.71 2021-12-16 Buy
ApexBio Technology C5006 UK1 1mg $312 2021-12-16 Buy
ApexBio Technology C5006 UK1 5mg $1325 2021-12-16 Buy
Cayman Chemical 20139 UK 1 ≥95% 1mg $279 2024-03-01 Buy
Cayman Chemical 20139 UK 1 ≥95% 5mg $1182 2024-03-01 Buy
TRC U700623 UK-1 250μg $110 2021-12-16 Buy
Usbiological 207430 UK-1 250ug $316 2021-12-16 Buy
Usbiological U0884-01 UK-1 1mg $513 2021-12-16 Buy

Properties

Melting point :209-210℃
Boiling point :541.4±30.0 °C(Predicted)
Density :1.396±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO;Soluble in dimethyl formamide
form :solid
pka :8.55±0.30(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

UK 1 is a metabolite from Streptomyces sp. 517-02 that demonstrates cytotoxic activity against various cancer cell lines, though it does not have antibacterial effects. It has been shown to inhibit topoisomerase II and also to inhibit hepatitis C viral replication.

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