UNC2170 Maleate
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- $42 - $1052
- Product name: UNC2170 Maleate
- CAS: 1648707-58-7
- MF: C14H21BrN2O
- MW: 313.23
- EINECS:
- MDL Number:MFCD29770818
- Synonyms:UNC2170 trifluoroacetate;UNC2170 Maleate;UNC-2170;Benzamide, 3-bromo-N-[3-[(1,1-dimethylethyl)amino]propyl]-;3-Bromo-N-(3-(tert-butylamino)propyl)benzamide;UNC-2170 HCl;UNC-2170,UNC2170,Kme readers,tudor domain,UNC 2170,H4K20me2,ligand,53BP1,inhibit,double-strand DNA breaks,Inhibitor;UNC-2170, 10 mM in DMSO
5 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product numberSYN5678
- Product descriptionUNC2170maleate
- Packaging50mg
- Price$1052
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17374
- Product descriptionUNC2170 (maleate) ≥95%
- Packaging25mg
- Price$668
- Updated2022-04-27
- Buy
- ManufacturerCayman Chemical
- Product number17374
- Product descriptionUNC2170 (maleate) ≥95%
- Packaging10mg
- Price$309
- Updated2022-04-27
- Buy
- ManufacturerCayman Chemical
- Product number17374
- Product descriptionUNC2170 (maleate) ≥95%
- Packaging5mg
- Price$165
- Updated2022-04-27
- Buy
- ManufacturerCayman Chemical
- Product number17374
- Product descriptionUNC2170 (maleate) ≥95%
- Packaging1mg
- Price$42
- Updated2022-04-27
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5678 | UNC2170maleate | 50mg | $1052 | 2021-12-16 | Buy |
| Cayman Chemical | 17374 | UNC2170 (maleate) ≥95% | 25mg | $668 | 2022-04-27 | Buy |
| Cayman Chemical | 17374 | UNC2170 (maleate) ≥95% | 10mg | $309 | 2022-04-27 | Buy |
| Cayman Chemical | 17374 | UNC2170 (maleate) ≥95% | 5mg | $165 | 2022-04-27 | Buy |
| Cayman Chemical | 17374 | UNC2170 (maleate) ≥95% | 1mg | $42 | 2022-04-27 | Buy |
Properties
Boiling point :419.6±30.0 °C(Predicted)
Density :1.233±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Water (up to 50 mg/ml).
form :solid
pka :14.63±0.46(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Density :1.233±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Water (up to 50 mg/ml).
form :solid
pka :14.63±0.46(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Safety Information
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Description
UNC-2170 (1648707-58-7), identified by screening, was found to be a μM ligand for 53BP1 which also demonstrated at least 17-fold selectivity for 53BP1 over other methyl-lysine binding proteins. The DNA damage response protein 53BP1 utilizes its tandem tudor domain to recognize dimethylated lysine 20 on histone (H4K20me2), a modification associated with double-strand DNA breaks. UNC-2170 functions as a 53BP1 antagonist in cell lysates and suppresses class switch recombination in whole cells, a process requiring a functioning 53BP1 tudor domain.1More related product prices
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