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ChemicalBook >> CAS DataBase List >> dihydroeponemycin

dihydroeponemycin

dihydroeponemycin price.
  • $158 - $1130
  • Product name: dihydroeponemycin
  • CAS: 126463-64-7
  • MF: C20H36N2O6
  • MW: 400.51
  • EINECS:
  • MDL Number:MFCD17215971
  • Synonyms:dihydroeponemycin;Dihydroeponemycin >=98% (HPLC);Heptanamide, N-[(1S)-1-(hydroxymethyl)-2-[[(1S)-1-[[(2R)-2-(hydroxymethyl)-2-oxiranyl]carbonyl]-3-methylbutyl]amino]-2-oxoethyl]-6-methyl-
9 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 1mg
  • 5MG
  • 25mg
  • ManufacturerAK Scientific
  • Product number3830BB
  • Product descriptionDihydroeponemycin
  • Packaging1mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0151789
  • Product descriptionDIHYDROEPONEMYCIN 95.00%
  • Packaging5MG
  • Price$501.86
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8172
  • Product descriptionDihydroeponemycin
  • Packaging1mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8172
  • Product descriptionDihydroeponemycin
  • Packaging5mg
  • Price$368
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8172
  • Product descriptionDihydroeponemycin
  • Packaging25mg
  • Price$945
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007805
  • Product descriptionDihydroeponemycin ≥98%
  • Packaging1mg
  • Price$244
  • Updated2022-04-27
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007805
  • Product descriptionDihydroeponemycin ≥98%
  • Packaging5mg
  • Price$1033
  • Updated2022-04-27
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD4321
  • Product descriptionDihydroeponemycin ≥98% (HPLC)
  • Packaging1mg
  • Price$302
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD4321
  • Product descriptionDihydroeponemycin ≥98% (HPLC)
  • Packaging5mg
  • Price$1130
  • Updated2025-07-31
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3830BB Dihydroeponemycin 1mg $403 2021-12-16 Buy
American Custom Chemicals Corporation CHM0151789 DIHYDROEPONEMYCIN 95.00% 5MG $501.86 2021-12-16 Buy
ApexBio Technology A8172 Dihydroeponemycin 1mg $158 2021-12-16 Buy
ApexBio Technology A8172 Dihydroeponemycin 5mg $368 2021-12-16 Buy
ApexBio Technology A8172 Dihydroeponemycin 25mg $945 2021-12-16 Buy
Cayman Chemical 10007805 Dihydroeponemycin ≥98% 1mg $244 2022-04-27 Buy
Cayman Chemical 10007805 Dihydroeponemycin ≥98% 5mg $1033 2022-04-27 Buy
Sigma-Aldrich D4321 Dihydroeponemycin ≥98% (HPLC) 1mg $302 2022-05-15 Buy
Sigma-Aldrich D4321 Dihydroeponemycin ≥98% (HPLC) 5mg $1130 2025-07-31 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: ≥1mg/mL
form :powder
color :off-white to light tan
optical activity :[α]/D ±35.7°

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Dihydroeponemycin is a natural, irreversible inhibitor of proteasomal degradation of proteins that acts by binding the IFN-γ-inducible proteins LMP2 and LMP7, as well as the constitutive proteasome subunit X. It potently inhibits both the chymotrypsin-like and PGPH activity, with 10-fold less inhibition of trypsin-like activity. Dihydroeponemycin does not inhibit calpain or trypsin and has minor effects on cathepsin B and chymotrypsin at higher concentrations. It is cell-permeable and induces apoptosis in bovine aortic endothelial cells.