macbecin I
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- $291 - $1928.08
- Product name: macbecin I
- CAS: 73341-72-7
- MF: C30H42N2O8
- MW: 558.67
- EINECS:
- MDL Number:
- Synonyms:macbecin I;(6S,15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methylgeldanamycin;(15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin;Geldanamycin, 6,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (15R)-;Macbecin
8 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 1
- 0.5mg
- 1G
- 2.5G
- 5G
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008044
- Product descriptionMACBECIN I 95.00%
- Packaging5G
- Price$1928.08
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008044
- Product descriptionMACBECIN I 95.00%
- Packaging2.5G
- Price$1473.14
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008044
- Product descriptionMACBECIN I 95.00%
- Packaging1G
- Price$983.52
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7259
- Product descriptionMacbecinI
- Packaging1mg
- Price$465
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22225
- Product descriptionMacbecin I ≥95%
- Packaging1mg
- Price$291
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number3061
- Product descriptionMacbecinI
- Packaging1
- Price$311
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM107525
- Product descriptionMacbecinI
- Packaging0.5mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number255749
- Product descriptionMacbecin I
- Packaging1mg
- Price$573
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0008044 | MACBECIN I 95.00% | 5G | $1928.08 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008044 | MACBECIN I 95.00% | 2.5G | $1473.14 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008044 | MACBECIN I 95.00% | 1G | $983.52 | 2021-12-16 | Buy |
| ApexBio Technology | B7259 | MacbecinI | 1mg | $465 | 2021-12-16 | Buy |
| Cayman Chemical | 22225 | Macbecin I ≥95% | 1mg | $291 | 2024-03-01 | Buy |
| Tocris | 3061 | MacbecinI | 1 | $311 | 2021-12-16 | Buy |
| TRC | M107525 | MacbecinI | 0.5mg | $1200 | 2021-12-16 | Buy |
| Usbiological | 255749 | Macbecin I | 1mg | $573 | 2021-12-16 | Buy |
Properties
Melting point :205-206 °C(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point :736.2±60.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :Soluble in DMSO > 10 mM
form :Powder
pka :8.62±0.70(Predicted)
Boiling point :736.2±60.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :Soluble in DMSO > 10 mM
form :Powder
pka :8.62±0.70(Predicted)
Safety Information
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Description
Macbecin I is an ansamycin antibiotic compound that inhibits Hsp90 activity (IC50 = 2 μM) by binding to the ATP-binding site. Macbecin I exhibits antitumor and cytocidal activities (IC50 ~ 0.4 μM) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Macbecin I displays higher potency and affinity than geldanamycin.More related product prices
Related product price
- macbecin I
$291-1928.08
