macbecin I

macbecin I Suppliers list
Company Name: BOC Sciences
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Email: inquiry@bocsci.com
Products Intro: Product Name:Macbecin I
CAS:73341-72-7
Purity:>98%
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801
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Products Intro: Product Name:Macbecin I;(15R)-6,17-DideMethoxy-15-Methoxy-6-Methyl-11-O-Methyl-geldanaMycin
CAS:73341-72-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: EMMX Biotechnology LLC  
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Products Intro: Product Name:Macbecin I
CAS:73341-72-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885
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Products Intro: Product Name:Macbecin I
CAS:73341-72-7
Purity:95% Package:10mg
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
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Products Intro: Product Name:Macbecin I
CAS:73341-72-7
Purity:0.98 Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
macbecin I Basic information
Product Name:macbecin I
Synonyms:macbecin I;(6S,15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methylgeldanamycin;(15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin;Geldanamycin, 6,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (15R)-
CAS:73341-72-7
MF:C30H42N2O8
MW:558.66
EINECS:
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Mol File:73341-72-7.mol
macbecin I Structure
macbecin I Chemical Properties
Melting point 205-206 °C(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point 736.2±60.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. Desiccate at -20°C
pka8.62±0.70(Predicted)
Safety Information
MSDS Information
macbecin I Usage And Synthesis
Biological ActivityAnsamycin antibiotic compound that inhibits Hsp90 activity (IC 50 = 2 μ M) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC 50 ~ 0.4 μ M) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher affinity and potency than geldanamycin (9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-carbamate ).
macbecin I Preparation Products And Raw materials
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N-DECYL METHACRYLAMIDE macbecin I